4CEV
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![BU of 4cev by Molmil](/molmil-images/mine/4cev) | ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX | Descriptor: | GUANIDINE, L-ornithine, MANGANESE (II) ION, ... | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-15 | Release date: | 1999-04-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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6CFI
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![BU of 6cfi by Molmil](/molmil-images/mine/6cfi) | Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion | Descriptor: | DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*CP*(T64)P*TP*GP*GP*AP*TP*GP*TP*TP*GP*AP*GP*TP*CP*A)-3'), DNA repair protein RAD4, DNA('-D(*TP*TP*GP*AP*CP*TP*CP*AP*AP*CP*AP*TP*CP*CP*AP*AP*AP*GP*CP*TP*AP*CP*AP*A)-'), ... | Authors: | Min, J, Jeffrey, P.D. | Deposit date: | 2018-02-15 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.36241913 Å) | Cite: | Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex. Nucleic Acids Res., 47, 2019
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6D0H
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![BU of 6d0h by Molmil](/molmil-images/mine/6d0h) | |
5BV0
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![BU of 5bv0 by Molmil](/molmil-images/mine/5bv0) | |
5BUZ
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![BU of 5buz by Molmil](/molmil-images/mine/5buz) | |
5BV1
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![BU of 5bv1 by Molmil](/molmil-images/mine/5bv1) | |
6E95
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![BU of 6e95 by Molmil](/molmil-images/mine/6e95) | |
6D0I
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![BU of 6d0i by Molmil](/molmil-images/mine/6d0i) | ParT: Prs ADP-ribosylating toxin bound to cognate antitoxin ParS. L48M ParT, SeMet-substituted complex. | Descriptor: | GLYCEROL, ParS: COG5642 (DUF2384) antitoxin fragment, ParT: COG5654 (RES domain) toxin | Authors: | Piscotta, F.J, Jeffrey, P.D, Link, A.J. | Deposit date: | 2018-04-10 | Release date: | 2019-01-09 | Last modified: | 2019-01-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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1YY8
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![BU of 1yy8 by Molmil](/molmil-images/mine/1yy8) | Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225 | Descriptor: | Cetuximab Fab Heavy chain, Cetuximab Fab Light chain | Authors: | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | Deposit date: | 2005-02-24 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
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1YY9
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![BU of 1yy9 by Molmil](/molmil-images/mine/1yy9) | Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ... | Authors: | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | Deposit date: | 2005-02-24 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.605 Å) | Cite: | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
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6E52
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![BU of 6e52 by Molmil](/molmil-images/mine/6e52) | |
5CEV
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![BU of 5cev by Molmil](/molmil-images/mine/5cev) | ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX | Descriptor: | GUANIDINE, LYSINE, MANGANESE (II) ION, ... | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | Deposit date: | 1999-03-16 | Release date: | 1999-04-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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8CUK
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![BU of 8cuk by Molmil](/molmil-images/mine/8cuk) | |
2IE3
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![BU of 2ie3 by Molmil](/molmil-images/mine/2ie3) | Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins | Descriptor: | MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | Deposit date: | 2006-09-17 | Release date: | 2006-11-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
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2IE4
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![BU of 2ie4 by Molmil](/molmil-images/mine/2ie4) | Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid | Descriptor: | MANGANESE (II) ION, OKADAIC ACID, Protein Phosphatase 2, ... | Authors: | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | Deposit date: | 2006-09-17 | Release date: | 2006-11-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
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2HV6
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![BU of 2hv6 by Molmil](/molmil-images/mine/2hv6) | |
1P22
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![BU of 1p22 by Molmil](/molmil-images/mine/1p22) | Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase | Descriptor: | Beta-catenin, F-box/WD-repeat protein 1A, Skp1 | Authors: | Wu, G, Xu, G, Schulman, B.A, Jeffrey, P.D, Harper, J.W, Pavletich, N.P. | Deposit date: | 2003-04-14 | Release date: | 2003-07-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of a beta-TrCP1-Skp1-beta-Catenin complex: destruction motif binding and lysine specificity of the SCFbeta-TrCP1 ubiquitin ligase Mol.Cell, 11, 2003
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1PI1
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![BU of 1pi1 by Molmil](/molmil-images/mine/1pi1) | Crystal structure of a human Mob1 protein; toward understanding Mob-regulated cell cycle pathways. | Descriptor: | Mob1A, ZINC ION | Authors: | Stavridi, E.S, Harris, K.G, Huyen, Y, Bothos, J, Voewerd, P.M, Stayrook, S.E, Jeffrey, P.D, Pavletich, N.P, Luca, F.C. | Deposit date: | 2003-05-29 | Release date: | 2003-09-30 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a human mob1 protein. Toward understanding mob-regulated cell cycle pathways. Structure, 11, 2003
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1P8T
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![BU of 1p8t by Molmil](/molmil-images/mine/1p8t) | Crystal structure of Nogo-66 Receptor | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Reticulon 4 receptor | Authors: | Barton, W.A, Liu, B.P, Tzvetkova, D, Jeffrey, P.D, Fournier, A.E, Sah, D, Cate, R, Strittmatter, S.M, Nikolov, D.B. | Deposit date: | 2003-05-07 | Release date: | 2003-05-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins Embo J., 22, 2003
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5VAE
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![BU of 5vae by Molmil](/molmil-images/mine/5vae) | |
5VAF
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![BU of 5vaf by Molmil](/molmil-images/mine/5vaf) | |
1MYK
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![BU of 1myk by Molmil](/molmil-images/mine/1myk) | CRYSTAL STRUCTURE, FOLDING, AND OPERATOR BINDING OF THE HYPERSTABLE ARC REPRESSOR MUTANT PL8 | Descriptor: | ARC REPRESSOR | Authors: | Schildbach, J.F, Milla, M.E, Jeffrey, P.D, Raumann, B.E, Sauer, R.T. | Deposit date: | 1994-10-12 | Release date: | 1995-01-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure, folding, and operator binding of the hyperstable Arc repressor mutant PL8. Biochemistry, 34, 1995
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5EP1
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![BU of 5ep1 by Molmil](/molmil-images/mine/5ep1) | Quorum-Sensing Signal Integrator LuxO - Catalytic Domain | Descriptor: | ACETATE ION, Putative repressor protein luxO | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
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5EP4
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![BU of 5ep4 by Molmil](/molmil-images/mine/5ep4) | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
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5EP3
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![BU of 5ep3 by Molmil](/molmil-images/mine/5ep3) | Quorum-Sensing Signal Integrator LuxO - Catalytic Domain Bound to CV-133 Inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2,2-dimethylpropyl 2-[(3-oxidanylidene-5-sulfanylidene-2~{H}-1,2,4-triazin-6-yl)amino]ethanoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
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