6VTW
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3MAW
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4DAG
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1SEB
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![BU of 1seb by Molmil](/molmil-images/mine/1seb) | COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB | Descriptor: | ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ENTEROTOXIN TYPE B, ... | Authors: | Jardetzky, T.S, Brown, J.H, Gorga, J.C, Stern, L.J, Urban, R.G, Chi, Y.I, Stauffacher, C, Strominger, J.L, Wiley, D.C. | Deposit date: | 1995-11-26 | Release date: | 1996-06-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. Nature, 368, 1994
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7MXI
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![BU of 7mxi by Molmil](/molmil-images/mine/7mxi) | IgE-Fc in complex with DARPins E2_79 and E3_53 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IgE Inhibitor E2_79, DARPin E3_53, ... | Authors: | Pennington, L.F, Jardetzky, T.J. | Deposit date: | 2021-05-19 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions. J.Allergy Clin.Immunol., 148, 2021
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5W0K
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3T1E
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![BU of 3t1e by Molmil](/molmil-images/mine/3t1e) | The structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a 4-helix bundle stalk | Descriptor: | Hemagglutinin-neuraminidase | Authors: | Yuan, P, Swanson, K, Leser, G.P, Paterson, R.G, Lamb, R.A, Jardetzky, T.S. | Deposit date: | 2011-07-21 | Release date: | 2011-09-07 | Last modified: | 2011-09-21 | Method: | X-RAY DIFFRACTION (3.301 Å) | Cite: | Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk. Proc.Natl.Acad.Sci.USA, 108, 2011
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3FD4
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2P6A
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![BU of 2p6a by Molmil](/molmil-images/mine/2p6a) | The structure of the Activin:Follistatin 315 complex | Descriptor: | Follistatin, Inhibin beta A chain, probable fragment of follistatin | Authors: | Lerch, T.F, Shimasaki, S, Woodruff, T.K, Jardetzky, T.S. | Deposit date: | 2007-03-16 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions. J.Biol.Chem., 282, 2007
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4JF7
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![BU of 4jf7 by Molmil](/molmil-images/mine/4jf7) | Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Welch, B.D, Yuan, P, Bose, S, Kors, C.A, Lamb, R.A, Jardetzky, T.S. | Deposit date: | 2013-02-27 | Release date: | 2013-09-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5018 Å) | Cite: | Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain. Plos Pathog., 9, 2013
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4WSG
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![BU of 4wsg by Molmil](/molmil-images/mine/4wsg) | Crystal Structure of Soluble WR PIV5 F-GCNt | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 | Authors: | Poor, T.A, Song, A.S, Welch, B.D, Kors, C.A, Jardetzky, T.S, Lamb, R.A. | Deposit date: | 2014-10-27 | Release date: | 2015-01-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Soluble WR PIV5 F-GCNt J.Virol., 89, 2015
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8TQI
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8TQK
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1NYU
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1NYS
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5HYS
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![BU of 5hys by Molmil](/molmil-images/mine/5hys) | Structure of IgE complexed with omalizumab | Descriptor: | Epididymis luminal protein 214, Ig epsilon chain C region, SULFATE ION, ... | Authors: | Pennington, L.F, Tarchevskaya, S.S, Sathiyamoorthy, K, Jardetzky, T.S. | Deposit date: | 2016-02-01 | Release date: | 2016-06-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. Nat Commun, 7, 2016
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3TSI
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![BU of 3tsi by Molmil](/molmil-images/mine/3tsi) | Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain | Descriptor: | Hemagglutinin-neuraminidase | Authors: | Bose, S, Welch, B.D, Kors, C.A, Yuan, P, Jardetzky, T.S, Lamb, R.A. | Deposit date: | 2011-09-13 | Release date: | 2011-10-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion. J.Virol., 85, 2011
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5EJB
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![BU of 5ejb by Molmil](/molmil-images/mine/5ejb) | Crystal structure of prefusion Hendra virus F protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ... | Authors: | Wong, J.W, Jardetzky, T.S, Paterson, R.G, Lamb, R.A. | Deposit date: | 2015-11-01 | Release date: | 2016-01-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form. Proc.Natl.Acad.Sci.USA, 113, 2016
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5U68
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6UQR
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![BU of 6uqr by Molmil](/molmil-images/mine/6uqr) | Complex of IgE and Ligelizumab | Descriptor: | IgE, Ligelizumab, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Tarchevskaya, S.S, Kleinboelting, S, Jardetzky, T.S. | Deposit date: | 2019-10-21 | Release date: | 2019-12-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.6502912 Å) | Cite: | The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab. Nat Commun, 11, 2020
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3QW9
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![BU of 3qw9 by Molmil](/molmil-images/mine/3qw9) | Crystal structure of betaglycan ZP-C domain | Descriptor: | Transforming growth factor beta receptor type 3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Lin, S.J, Jardetzky, T.S. | Deposit date: | 2011-02-27 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-{beta} binding. Proc.Natl.Acad.Sci.USA, 108, 2011
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3PHF
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7SHZ
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![BU of 7shz by Molmil](/molmil-images/mine/7shz) | IgE-Fc in complex with HAE | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Pennington, L.F, Jardetzky, T.J, Kleinboelting, S. | Deposit date: | 2021-10-11 | Release date: | 2021-12-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
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7SHY
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![BU of 7shy by Molmil](/molmil-images/mine/7shy) | IgE-Fc in complex with omalizumab scFv | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, IgE Fc, ... | Authors: | Pennington, L.F, Jardetzky, T.J, Kleinboelting, S. | Deposit date: | 2021-10-11 | Release date: | 2021-12-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
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7SI0
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![BU of 7si0 by Molmil](/molmil-images/mine/7si0) | IgE-Fc in complex with 813 | Descriptor: | 813 Variable fragment Heavy chain, 813 Variable fragment Light chain, IgE Fc, ... | Authors: | Pennington, L.F, Jardetzky, T.J, Kleinboelting, S. | Deposit date: | 2021-10-12 | Release date: | 2021-12-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
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