5HYS

Structure of IgE complexed with omalizumab

Summary for 5HYS

Entry DOI	10.2210/pdb5hys/pdb
Descriptor	Epididymis luminal protein 214, Uncharacterized protein, Ig epsilon chain C region, ... (6 entities in total)
Functional Keywords	immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	12
Total formula weight	301108.26
Authors	Pennington, L.F.,Tarchevskaya, S.S.,Sathiyamoorthy, K.,Jardetzky, T.S. (deposition date: 2016-02-01, release date: 2016-06-01, Last modification date: 2023-09-27)
Primary citation	Pennington, L.F.,Tarchevskaya, S.,Brigger, D.,Sathiyamoorthy, K.,Graham, M.T.,Nadeau, K.C.,Eggel, A.,Jardetzky, T.S. Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. Nat Commun, 7:11610-11610, 2016 Cited by PubMed: 27194387 DOI: 10.1038/ncomms11610 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation