7N5W
| ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 23) | Descriptor: | 1,2-ETHANEDIOL, DNA Strand I, DNA Strand II, ... | Authors: | Horton, J.R, Ren, R, Cheng, X. | Deposit date: | 2021-06-06 | Release date: | 2022-06-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia. J.Biol.Chem., 299, 2023
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7N5V
| ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 20) | Descriptor: | DNA Strand I, DNA Strand II, ZINC ION, ... | Authors: | Horton, J.R, Ren, R, Cheng, X. | Deposit date: | 2021-06-06 | Release date: | 2022-06-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia. J.Biol.Chem., 299, 2023
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2I7A
| Domain IV of Human Calpain 13 | Descriptor: | CALCIUM ION, Calpain 13, GLYCEROL, ... | Authors: | Walker, J.R, Ng, K, Davis, T.L, Ravulapalli, R, Butler-cole, C, Finerty Jr, P.J, Newman, E.M, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-08-30 | Release date: | 2006-09-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Human Calpain 13 To be Published
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2JKP
| Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine | Descriptor: | 1,2-ETHANEDIOL, ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), CALCIUM ION, ... | Authors: | Gloster, T.M, Turkenburg, J.P, Potts, J.R, Henrissat, B, Davies, G.J. | Deposit date: | 2008-08-29 | Release date: | 2008-09-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora. Chem.Biol., 15, 2008
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2JN8
| Solution NMR structure of Q8ZRJ2 from Salmonella typhimurium. Northeast Structural Genomics target StR65. | Descriptor: | Putative cytoplasmic protein | Authors: | Aramini, J.M, Cort, J.R, Ho, C.K, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-12-29 | Release date: | 2007-01-30 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of Q8ZRJ2 from Salmonella typhimurium. Northeast Structural Genomics target StR65. To be Published
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2JNE
| NMR structure of E.coli YfgJ modelled with two Zn+2 bound. Northeast Structural Genomics Consortium Target ER317. | Descriptor: | Hypothetical protein yfgJ, ZINC ION | Authors: | Ramelot, T.A, Cort, J.R, Yee, A.A, Semesi, A, Lukin, J.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-01-12 | Release date: | 2007-02-13 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | NMR structure of E.coli YfgJ bound to two Zn+2. To be Published
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2JO6
| NMR structure of the E.coli protein NirD, Northeast Structural Genomics target ET100 | Descriptor: | Nitrite reductase [NAD(P)H] small subunit | Authors: | Ramelot, T.A, Cort, J.R, Yee, A.A, Guido, V, Lukin, J.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-02-21 | Release date: | 2007-03-27 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structure of E.coli NirD. To be Published
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2JR2
| Solution NMR structure of homodimer CPS_2611 from Colwellia psychrerythraea. Northeast Structural Genomics Consortium target CsR4. | Descriptor: | UPF0352 protein CPS_2611 | Authors: | Ramelot, T.A, Cort, J.R, Wang, H, Nwosu, C, Cunningham, K, Owens, L, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-19 | Release date: | 2007-07-03 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of homodimer CPS_2611 from Colwellia psychrerythraea. To be Published
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2JKA
| Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron | Descriptor: | 1,2-ETHANEDIOL, ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), CALCIUM ION | Authors: | Gloster, T.M, Turkenburg, J.P, Potts, J.R, Henrissat, B, Davies, G.J. | Deposit date: | 2008-08-23 | Release date: | 2008-09-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora. Chem.Biol., 15, 2008
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2KMM
| Solution NMR structure of the TGS domain of PG1808 from Porphyromonas gingivalis. Northeast Structural Genomics Consortium Target PgR122A (418-481) | Descriptor: | Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Lee, D, Ciccosanti, C, Hamilton, K, Nair, R, Rost, B, Acton, T.B, Xiao, R, Swapna, G, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-07-31 | Release date: | 2009-11-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the TGS domain of PG1808 from
Porphyromonas gingivalis. Northeast Structural Genomics Consortium Target
PgR122A (418-481) To be Published
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7NJZ
| X-ray crystallography study of RoAb13 which binds to PIYDIN, a part of the CCR5 N terminal domain | Descriptor: | Antibody RoAb13 Heavy Chain, Antibody RoAb13 Light Chain, Region from C-C chemokine receptor type 5 N-terminal domain | Authors: | Helliwell, J.R, Chayen, N, Saridakis, E, Govada, L. | Deposit date: | 2021-02-17 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5. Iucrj, 8, 2021
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2HE9
| Structure of the peptidylprolyl isomerase domain of the human NK-tumour recognition protein | Descriptor: | NK-tumor recognition protein, SULFATE ION | Authors: | Walker, J.R, Davis, T, Newman, E.M, MacKenzie, F, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2006-06-21 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PLoS Biol., 8, 2010
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2HEQ
| NMR Structure of Bacillus subtilis protein YorP, Northeast Structural Genomics Target SR399. | Descriptor: | YorP protein | Authors: | Ramelot, T.A, Cort, J.R, Wang, D, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.M, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-21 | Release date: | 2006-08-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR Structure of Bacillus subtilis protein YorP, Northeast Structural Genomics Target SR399. To be Published
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7OD1
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7NT8
| Influenza virus H3N2 nucleoprotein - R416A mutant | Descriptor: | Glutathione S-transferase class-mu 26 kDa isozyme,Nucleoprotein | Authors: | Keown, J.R, Knight, M.L, Grimes, J.M, Fodor, E. | Deposit date: | 2021-03-09 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structure of an H3N2 influenza virus nucleoprotein. Acta Crystallogr.,Sect.F, 77, 2021
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2KJ7
| Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles | Descriptor: | Islet amyloid polypeptide | Authors: | Nanga, R, Brender, J.R, Xu, J, Hartman, K, Subramanian, V, Ramamoorthy, A. | Deposit date: | 2009-05-22 | Release date: | 2009-06-23 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy. J.Am.Chem.Soc., 131, 2009
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2KKO
| Solution NMR structure of the homodimeric winged helix-turn-helix DNA-binding domain (fragment 1-100) Mb0332 from Mycobacterium bovis, a possible ArsR-family transcriptional regulator. Northeast Structural Genomics Consortium Target MbR242E. | Descriptor: | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY) | Authors: | Ramelot, T.A, Cort, J.R, Wang, D, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-26 | Release date: | 2009-08-11 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the homodimeric winged helix-turn-helix DNA-binding domain (fragment 1-100) Mb0332 from Mycobacterium bovis, a possible ArsR-family transcriptional regulator. Northeast Structural Genomics Consortium Target MbR242E. To be Published
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7MF3
| Structure of the autoinhibited state of smooth muscle myosin-2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin light polypeptide 6, ... | Authors: | Heissler, S.M, Arora, A.S, Billington, N, Sellers, J.R, Chinthalapudi, K. | Deposit date: | 2021-04-08 | Release date: | 2022-01-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of the autoinhibited state of myosin-2. Sci Adv, 7, 2021
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2KF2
| Solution NMR structure of of Streptomyces coelicolor polyketide cyclase SCO5315. Northeast Structural Genomics Consortium target RR365 | Descriptor: | Putative polyketide cyclase | Authors: | Cort, J.R, Ramelot, T.A, Ding, K, Wang, H, Jiang, M, Maglaqui, M, Xiao, R, Nair, R, Baran, M.C, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-02-11 | Release date: | 2009-05-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of Streptomyces coelicolor polyketide cyclase SCO5315 To be Published
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2J98
| Human coronavirus 229E non structural protein 9 cys69ala mutant (Nsp9) | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, REPLICASE POLYPROTEIN 1AB | Authors: | Ponnusamy, R, Mesters, J.R, Moll, R, Hilgenfeld, R. | Deposit date: | 2006-11-03 | Release date: | 2007-11-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Variable Oligomerization Modes in Coronavirus Non-Structural Protein 9. J.Mol.Biol., 383, 2008
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2J97
| Human coronavirus 229E non structural protein 9 (Nsp9) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, REPLICASE POLYPROTEIN 1AB, SULFATE ION | Authors: | Ponnusamy, R, Mesters, J.R, Moll, R, Hilgenfeld, R. | Deposit date: | 2006-11-03 | Release date: | 2007-11-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Variable Oligomerization Modes in Coronavirus Non-Structural Protein 9. J.Mol.Biol., 383, 2008
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2IRW
| Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) with NADP and Adamantane Ether Inhibitor | Descriptor: | (1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Longenecker, K.L, Patel, J.R, Russell, J, Qin, W. | Deposit date: | 2006-10-16 | Release date: | 2007-01-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation. Bioorg.Med.Chem.Lett., 17, 2007
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2H5M
| NMR Solution Structure of a GCN5-like putative N-acetyltransferase from Staphylococcus aureus complexed with acetyl-CoA. Northeast Structural Genomics Consortium Target ZR31 | Descriptor: | ACETYL COENZYME *A, Acetyltransferase, GNAT family | Authors: | Cort, J.R, Ramelot, T.A, Acton, T.B, Ma, L, Xiao, R.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-05-26 | Release date: | 2006-11-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins J.Struct.Funct.Genom., 9, 2008
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7OI1
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2H01
| PY00414- Plasmodium yoelii thioredoxin peroxidase I | Descriptor: | 2-CYS PEROXIREDOXIN | Authors: | Artz, J, Qiu, W, Min, J.R, Dong, A, Lew, J, Melone, M, Alam, Z, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2006-05-12 | Release date: | 2006-05-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of PY00414 - a Plasmodium yoelii thioredoxin peroxidase I To be Published
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