7SSV
 
 | | Structure of human Kv1.3 with Fab-ShK fusion | | 分子名称: | Fab-ShK fusion, heavy chain, light chain, ... | | 著者 | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | | 登録日 | 2021-11-11 | | 公開日 | 2022-06-29 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
|
|
7JZ2
 | | Succinate: quinone oxidoreductase SQR from E.coli K12 | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | | 著者 | Lyu, M, Su, C.-C, Morgan, C.E, Bolla, J.R, Robinson, C.V, Yu, E.W. | | 登録日 | 2020-09-01 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins.
Nat.Methods, 18, 2021
|
|
3PTK
 | | The crystal structure of rice (Oryza sativa L.) Os4BGlu12 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase Os4BGlu12, ZINC ION | | 著者 | Sansenya, S, Opassiri, R, Kuaprasert, B, Chen, C.J, Ketudat Cairns, J.R. | | 登録日 | 2010-12-03 | | 公開日 | 2011-05-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | The crystal structure of rice (Oryza sativa L.) Os4BGlu12, an oligosaccharide and tuberonic acid glucoside-hydrolyzing beta-glucosidase with significant thioglucohydrolase activity
Arch.Biochem.Biophys., 510, 2011
|
|
3PU8
 | | PHF2 Jumonji-NOG-Fe(II) complex | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FE (III) ION, ... | | 著者 | Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X. | | 登録日 | 2010-12-03 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.943 Å) | | 主引用文献 | Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
|
|
2EZG
 | | SOLUTION STRUCTURE OF A COMPLEX OF THE THIRD DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, 35 STRUCTURES | | 分子名称: | DNA (5'-D(*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3'), HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y | | 著者 | Clore, G.M, Huth, J.R, Bewley, C, Gronenborn, A.M. | | 登録日 | 1997-06-04 | | 公開日 | 1997-10-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif.
Nat.Struct.Biol., 4, 1997
|
|
2EZF
 | | SOLUTION STRUCTURE OF A COMPLEX OF THE THIRD DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | DNA (5'-D(*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3'), HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y | | 著者 | Clore, G.M, Huth, J.R, Bewley, C, Gronenborn, A.M. | | 登録日 | 1997-06-04 | | 公開日 | 1997-10-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif.
Nat.Struct.Biol., 4, 1997
|
|
4W4M
 | |
1DAJ
 | | COMPARISON OF TERNARY COMPLEXES OF PNEUMOCYSTIS CARINII AND WILD TYPE HUMAN DIHYDROFOLATE REDUCTASE WITH COENZYME NADPH AND A NOVEL CLASSICAL ANTITUMOR FURO[2,3D]PYRIMIDINE ANTIFOLATE | | 分子名称: | DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Gangjee, A, Devraj, R, Queener, S.F, Blakley, R.L. | | 登録日 | 1997-07-29 | | 公開日 | 1997-12-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate.
Acta Crystallogr.,Sect.D, 53, 1997
|
|
2FV4
 | |
2JKE
 | | Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with deoxynojirimycin | | 分子名称: | 1,2-ETHANEDIOL, 1-DEOXYNOJIRIMYCIN, ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), ... | | 著者 | Gloster, T.M, Turkenburg, J.P, Potts, J.R, Henrissat, B, Davies, G.J. | | 登録日 | 2008-08-28 | | 公開日 | 2008-09-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.
Chem.Biol., 15, 2008
|
|
2JJ2
 | | The Structure of F1-ATPase inhibited by quercetin. | | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE GAMMA CHAIN, ... | | 著者 | Gledhill, J.R, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. | | 登録日 | 2007-07-03 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mechanism of Inhibition of Bovine F1-ATPase by Resveratrol and Related Polyphenols.
Proc.Natl.Acad.Sci.USA, 104, 2007
|
|
2JKP
 | | Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine | | 分子名称: | 1,2-ETHANEDIOL, ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), CALCIUM ION, ... | | 著者 | Gloster, T.M, Turkenburg, J.P, Potts, J.R, Henrissat, B, Davies, G.J. | | 登録日 | 2008-08-29 | | 公開日 | 2008-09-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.
Chem.Biol., 15, 2008
|
|
3Q2P
 | | Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix | | 分子名称: | Monellin chain B/Monellin chain A chimeric protein, SODIUM ION | | 著者 | Templeton, C.M, Hobbs, J.R, Munger, S.D, Conn, G.L. | | 登録日 | 2010-12-20 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.341 Å) | | 主引用文献 | Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.
Chem Senses, 36, 2011
|
|
3PHE
 | | HCV NS5B with a bound quinolone inhibitor | | 分子名称: | 4-chlorobenzyl 6-fluoro-7-(4-methylpiperazin-1-yl)-1-[4-(methylsulfonyl)benzyl]-4-oxo-1,4-dihydroquinoline-3-carboxylate, HCV encoded nonstructural 5B protein | | 著者 | Somoza, J.R, To, N, Lehoux, I. | | 登録日 | 2010-11-03 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Quinolones as HCV NS5B polymerase inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
|
|
7SP2
 | | Structure of PLS A-domain (residues 391-656; 513-518 deletion mutant) from Staphylococcus aureus | | 分子名称: | CALCIUM ION, Plasmin Sensitive Protein Pls | | 著者 | Clark, L, Whelan, F, Atkin, K.E, Brentnall, A.S, Dodson, E.J, Turkenburg, J.P, Potts, J.R. | | 登録日 | 2021-11-02 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure of PLS A-domain (residues 391-65) from Staphylococcus aureus
Not Published
|
|
2JN8
 | | Solution NMR structure of Q8ZRJ2 from Salmonella typhimurium. Northeast Structural Genomics target StR65. | | 分子名称: | Putative cytoplasmic protein | | 著者 | Aramini, J.M, Cort, J.R, Ho, C.K, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-12-29 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of Q8ZRJ2 from Salmonella typhimurium. Northeast Structural Genomics target StR65.
To be Published
|
|
2JNE
 | | NMR structure of E.coli YfgJ modelled with two Zn+2 bound. Northeast Structural Genomics Consortium Target ER317. | | 分子名称: | Hypothetical protein yfgJ, ZINC ION | | 著者 | Ramelot, T.A, Cort, J.R, Yee, A.A, Semesi, A, Lukin, J.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-01-12 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of E.coli YfgJ bound to two Zn+2.
To be Published
|
|
1D44
 | | DNA DODECAMER C-G-C-G-A-A-T-T-C-G-C-G/HOECHST 33258 COMPLEX: 0 DEGREES C, PIPERAZINE DOWN | | 分子名称: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | | 著者 | Quintana, J.R, Lipanov, A.A, Dickerson, R.E. | | 登録日 | 1991-06-04 | | 公開日 | 1992-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Low-temperature crystallographic analyses of the binding of Hoechst 33258 to the double-helical DNA dodecamer C-G-C-G-A-A-T-T-C-G-C-G.
Biochemistry, 30, 1991
|
|
3P8D
 | | Crystal structure of the second Tudor domain of human PHF20 (homodimer form) | | 分子名称: | Medulloblastoma antigen MU-MB-50.72 | | 著者 | Cui, G, Lee, J, Thompson, J.R, Botuyan, M.V, Mer, G. | | 登録日 | 2010-10-13 | | 公開日 | 2011-06-22 | | 最終更新日 | 2012-09-26 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Nat.Struct.Mol.Biol., 19, 2012
|
|
2HGK
 | | Solution NMR Structure of protein YqcC from E. coli: Northeast Structural Genomics Consortium target ER225 | | 分子名称: | Hypothetical protein yqcC | | 著者 | Cort, J.R, Wang, D, Shetty, K, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-06-27 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of protein YqcC from E.coli
To be Published
|
|
7L4X
 | |
2JO6
 | | NMR structure of the E.coli protein NirD, Northeast Structural Genomics target ET100 | | 分子名称: | Nitrite reductase [NAD(P)H] small subunit | | 著者 | Ramelot, T.A, Cort, J.R, Yee, A.A, Guido, V, Lukin, J.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-02-21 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of E.coli NirD.
To be Published
|
|
7L4Y
 | |
7L4V
 | |
7JJO
 | | Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor | | 分子名称: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Su, M, Zhu, L, Zhang, Y, Paknejad, N, Dey, R, Huang, J, Lee, M.Y, Williams, D, Jordan, K.D, Eng, E.T, Ernst, O.P, Meyerson, J.R, Hite, R.K, Walz, T, Liu, W, Huang, X.Y. | | 登録日 | 2020-07-27 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor.
Mol.Cell, 80, 2020
|
|
