3P8D
Crystal structure of the second Tudor domain of human PHF20 (homodimer form)
Summary for 3P8D
| Entry DOI | 10.2210/pdb3p8d/pdb |
| Descriptor | Medulloblastoma antigen MU-MB-50.72 (2 entities in total) |
| Functional Keywords | tudor domain, lysine-methylated p53 binding, histone binding, protein binding |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 15179.16 |
| Authors | Cui, G.,Lee, J.,Thompson, J.R.,Botuyan, M.V.,Mer, G. (deposition date: 2010-10-13, release date: 2011-06-22, Last modification date: 2012-09-26) |
| Primary citation | Cui, G.,Park, S.,Badeaux, A.I.,Kim, D.,Lee, J.,Thompson, J.R.,Yan, F.,Kaneko, S.,Yuan, Z.,Botuyan, M.V.,Bedford, M.T.,Cheng, J.Q.,Mer, G. PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nat.Struct.Mol.Biol., 19:916-924, 2012 Cited by PubMed: 22864287DOI: 10.1038/nsmb.2353 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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