7L4V

C-terminal bZIP domain of human C/EBPbeta Bound to DNA with Consensus Recognition with GT Mismatch

Summary for 7L4V

Entry DOI	10.2210/pdb7l4v/pdb
Descriptor	CCAAT/enhancer-binding protein beta, DNA Strand 1, DNA Strand 2, ... (5 entities in total)
Functional Keywords	bzip transciption factor dna methylation cpa methylation protein-dna complex, transcription, transcription-dna complex, g-t dna mismatch, transcription/dna
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	28771.25
Authors	Horton, J.R.,Cheng, X. (deposition date: 2020-12-21, release date: 2021-11-03, Last modification date: 2023-10-18)
Primary citation	Yang, J.,Horton, J.R.,Akdemir, K.C.,Li, J.,Huang, Y.,Kumar, J.,Blumenthal, R.M.,Zhang, X.,Cheng, X. Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations. Nucleic Acids Res., 49:5084-5094, 2021 Cited by PubMed: 33877329 DOI: 10.1093/nar/gkab276 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation