5CXQ
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![BU of 5cxq by Molmil](/molmil-images/mine/5cxq) | Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in APO form | 分子名称: | Purine nucleoside phosphorylase | 著者 | Torini, J.R, Romanello, L, Bird, L, Owens, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2015-07-29 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs. PLoS ONE, 13, 2018
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4LT2
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![BU of 4lt2 by Molmil](/molmil-images/mine/4lt2) | HEWL co-crystallized with Carboplatin in non-NaCl conditions: crystal 2 processed using the EVAL software package | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, Lysozyme C, ... | 著者 | Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Schreurs, A.M.M, Helliwell, J.R. | 登録日 | 2013-07-23 | 公開日 | 2014-07-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Carboplatin binding to a model protein in non-NaCl conditions to eliminate partial conversion to cisplatin, and the use of different criteria to choose the resolution limit To be Published
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2BCE
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![BU of 2bce by Molmil](/molmil-images/mine/2bce) | CHOLESTEROL ESTERASE FROM BOS TAURUS | 分子名称: | CHOLESTEROL ESTERASE | 著者 | Chen, J.C.-H, Miercke, L.J.W, Krucinski, J, Starr, J.R, Saenz, G, Wang, X, Spilburg, C.A, Lange, L.G, Ellsworth, J.L, Stroud, R.M. | 登録日 | 1998-01-28 | 公開日 | 1999-02-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of bovine pancreatic cholesterol esterase at 1.6 A: novel structural features involved in lipase activation. Biochemistry, 37, 1998
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3LMN
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![BU of 3lmn by Molmil](/molmil-images/mine/3lmn) | Oligomeric structure of the DUSP domain of human USP15 | 分子名称: | ACETIC ACID, FORMIC ACID, Ubiquitin carboxyl-terminal hydrolase 15 | 著者 | Walker, J.R, Asinas, A, Avvakumov, G.V, Alenkin, D, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S. | 登録日 | 2010-01-31 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal Structure of the Human Ubiquitin-Specific Protease 15 DUSP Domain To be Published
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4MGS
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![BU of 4mgs by Molmil](/molmil-images/mine/4mgs) | BiXyn10A CBM1 APO | 分子名称: | Putative glycosyl hydrolase family 10 | 著者 | Chekan, J.R, Nair, S.K. | 登録日 | 2013-08-28 | 公開日 | 2014-08-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes. Proc.Natl.Acad.Sci.USA, 111, 2014
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8EHW
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5CT5
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![BU of 5ct5 by Molmil](/molmil-images/mine/5ct5) | Wild-type Bacillus subtilis lipase A with 10% [BMIM][Cl] | 分子名称: | 1-butyl-3-methyl-1H-imidazol-3-ium, CHLORIDE ION, SULFATE ION, ... | 著者 | Nordwald, E.M, Plaks, J.G, Snell, J.R, Sousa, M.C, Kaar, J.L. | 登録日 | 2015-07-23 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Crystallographic Investigation of Imidazolium Ionic Liquid Effects on Enzyme Structure. Chembiochem, 16, 2015
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7NT8
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![BU of 7nt8 by Molmil](/molmil-images/mine/7nt8) | Influenza virus H3N2 nucleoprotein - R416A mutant | 分子名称: | Glutathione S-transferase class-mu 26 kDa isozyme,Nucleoprotein | 著者 | Keown, J.R, Knight, M.L, Grimes, J.M, Fodor, E. | 登録日 | 2021-03-09 | 公開日 | 2021-07-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structure of an H3N2 influenza virus nucleoprotein. Acta Crystallogr.,Sect.F, 77, 2021
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3EBB
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![BU of 3ebb by Molmil](/molmil-images/mine/3ebb) | PLAP/P97 complex | 分子名称: | MAGNESIUM ION, PHOSPHOLIPASE A2-ACTIVATING PROTEIN, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE (TER ATP | 著者 | Walker, J.R, Qiu, L, Akutsu, M, Slessarev, Y, Amaya, M.F, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-08-27 | 公開日 | 2009-02-24 | 最終更新日 | 2014-04-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and function of the PLAA/Ufd3-p97/Cdc48 complex. J.Biol.Chem., 285, 2010
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1ULA
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![BU of 1ula by Molmil](/molmil-images/mine/1ula) | APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | 分子名称: | PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | 著者 | Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E. | 登録日 | 1991-11-05 | 公開日 | 1993-01-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors. Proc.Natl.Acad.Sci.USA, 88, 1991
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3EML
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![BU of 3eml by Molmil](/molmil-images/mine/3eml) | The 2.6 A Crystal Structure of a Human A2A Adenosine Receptor bound to ZM241385. | 分子名称: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Human Adenosine A2A receptor/T4 lysozyme chimera, STEARIC ACID, ... | 著者 | Jaakola, V.-P, Griffith, M.T, Hanson, M.A, Cherezov, V, Chien, E.Y.T, Lane, J.R, Ijzerman, A.P, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | 登録日 | 2008-09-24 | 公開日 | 2008-10-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist. Science, 322, 2008
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1ULB
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![BU of 1ulb by Molmil](/molmil-images/mine/1ulb) | APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | 分子名称: | GUANINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | 著者 | Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E. | 登録日 | 1991-11-05 | 公開日 | 1993-01-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors. Proc.Natl.Acad.Sci.USA, 88, 1991
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3EJW
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![BU of 3ejw by Molmil](/molmil-images/mine/3ejw) | Crystal Structure of the Sinorhizobium meliloti AI-2 receptor, SmLsrB | 分子名称: | (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran, SmLsrB | 著者 | Miller, S.T, McAuley, J.R, Pereira, C, Xavier, K.B, Taga, M.E. | 登録日 | 2008-09-18 | 公開日 | 2008-12-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria. Mol.Microbiol., 70, 2008
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3MO0
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![BU of 3mo0 by Molmil](/molmil-images/mine/3mo0) | Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E11 | 分子名称: | 1,2-ETHANEDIOL, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... | 著者 | Chang, Y, Horton, J.R, Cheng, X. | 登録日 | 2010-04-22 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
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4HZP
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![BU of 4hzp by Molmil](/molmil-images/mine/4hzp) | The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold | 分子名称: | Bifunctional methylmalonyl-CoA:ACP Acyltransferase/Decarboxylase, CHLORIDE ION, COENZYME A, ... | 著者 | Lohman, J.R, Bingman, C.A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-15 | 公開日 | 2013-01-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold. Biochemistry, 52, 2013
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4LK4
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5A42
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![BU of 5a42 by Molmil](/molmil-images/mine/5a42) | Cryo-EM single particle 3D reconstruction of the native conformation of E. coli alpha-2-macroglobulin (ECAM) | 分子名称: | UNCHARACTERIZED LIPOPROTEIN YFHM | 著者 | Garcia-Ferrer, I, Arede, P, Gomez-Blanco, J, Luque, D, Duquerroy, S, Caston, J.R, Goulas, T, Gomis-Ruth, F.X. | 登録日 | 2015-06-04 | 公開日 | 2015-07-29 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (16 Å) | 主引用文献 | Structural and Functional Insights Into Escherichia Coli Alpha2- Macroglobulin Endopeptidase Snap-Trap Inhibition. Proc.Natl.Acad.Sci.USA, 112, 2015
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5FJB
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![BU of 5fjb by Molmil](/molmil-images/mine/5fjb) | Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site | 分子名称: | GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | 著者 | Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P. | 登録日 | 2015-10-07 | 公開日 | 2016-03-16 | 最終更新日 | 2017-08-23 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site. Nat.Commun., 7, 2016
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6VL0
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![BU of 6vl0 by Molmil](/molmil-images/mine/6vl0) | Crystal Structure of the N-prenyltransferase DabA in Complex with GSPP and Mn2+ | 分子名称: | DabA, GERANYL S-THIOLODIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Chekan, J.R, Noel, J.P, Moore, B.S. | 登録日 | 2020-01-22 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into anN-prenyltransferase. Proc.Natl.Acad.Sci.USA, 117, 2020
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4HZN
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![BU of 4hzn by Molmil](/molmil-images/mine/4hzn) | The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifunctional Methylmalonyl-CoA:ACP Acyltransferase/Decarboxylase, GLYCEROL, ... | 著者 | Lohman, J.R, Bingman, C.A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-15 | 公開日 | 2013-01-30 | 最終更新日 | 2013-02-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold. Biochemistry, 52, 2013
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3MVD
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![BU of 3mvd by Molmil](/molmil-images/mine/3mvd) | Crystal structure of the chromatin factor RCC1 in complex with the nucleosome core particle | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | 著者 | Makde, R.D, England, J.R, Yennawar, H.P, Tan, S. | 登録日 | 2010-05-04 | 公開日 | 2010-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of RCC1 chromatin factor bound to the nucleosome core particle. Nature, 467, 2010
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3BRB
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![BU of 3brb by Molmil](/molmil-images/mine/3brb) | Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Walker, J.R, Huang, X, Finerty Jr, P.J, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-12-21 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J.Struct.Biol., 165, 2009
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3C8X
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![BU of 3c8x by Molmil](/molmil-images/mine/3c8x) | Crystal structure of the ligand binding domain of human Ephrin A2 (Epha2) receptor protein kinase | 分子名称: | Ephrin type-A receptor 2 | 著者 | Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-02-14 | 公開日 | 2008-03-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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4G4B
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![BU of 4g4b by Molmil](/molmil-images/mine/4g4b) | Room temperature X-ray diffraction study of cisplatin binding to HEWL in DMSO media with NAG after 7 months of crystal storage | 分子名称: | CHLORIDE ION, Cisplatin, DIMETHYL SULFOXIDE, ... | 著者 | Tanley, S.W.M, Schreurs, A.M.M, Kroon-Batenburg, L.M.J, Helliwell, J.R. | 登録日 | 2012-07-16 | 公開日 | 2012-11-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Room-temperature X-ray diffraction studies of cisplatin and carboplatin binding to His15 of HEWL after prolonged chemical exposure. Acta Crystallogr.,Sect.F, 68, 2012
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1Z8O
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![BU of 1z8o by Molmil](/molmil-images/mine/1z8o) | Ferrous dioxygen complex of the wild-type cytochrome P450eryF | 分子名称: | 6-DEOXYERYTHRONOLIDE B, 6-deoxyerythronolide B hydroxylase, OXYGEN MOLECULE, ... | 著者 | Nagano, S, Cupp-Vickery, J.R, Poulos, T.L. | 登録日 | 2005-03-31 | 公開日 | 2005-04-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF. J.Biol.Chem., 280, 2005
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