5LCB
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![BU of 5lcb by Molmil](/molmil-images/mine/5lcb) | In situ atomic-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum obtained combining solid-state NMR spectroscopy, cryo electron microscopy and polarization spectroscopy | Descriptor: | BACTERIOCHLOROPHYLL A, Bacteriochlorophyll c-binding protein | Authors: | Nielsen, J.T, Kulminskaya, N.V, Bjerring, M, Linnanto, J.M, Ratsep, M, Pedersen, M, Lambrev, P.H, Dorogi, M, Garab, G, Thomsen, K, Jegerschold, C, Frigaard, N.U, Lindahl, M, Nielsen, N.C. | Deposit date: | 2016-06-20 | Release date: | 2016-07-27 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (26.5 Å), SOLID-STATE NMR | Cite: | In situ high-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum. Nat Commun, 7, 2016
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5MCS
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![BU of 5mcs by Molmil](/molmil-images/mine/5mcs) | Solution structure and dynamics of the outer membrane cytochrome OmcF from Geobacter sulfurreducens | Descriptor: | HEME C, Lipoprotein cytochrome c, 1 heme-binding site | Authors: | Dantas, J.M, Silva, M.A, Morgado, L, Pantoja-Uceda, D, Turner, D.L, Bruix, M, Salgueiro, C.A. | Deposit date: | 2016-11-10 | Release date: | 2017-04-12 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of the outer membrane cytochrome OmcF from Geobacter sulfurreducens. Biochim. Biophys. Acta, 1858, 2017
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5MLM
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![BU of 5mlm by Molmil](/molmil-images/mine/5mlm) | Plantago Major multifunctional oxidoreductase V150M mutant in complex with progesterone and NADP+ | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE, Progesterone 5-beta-reductase | Authors: | Fellows, R, Russo, C.M, Lee, S.G, Jez, J.M, Chisholm, J.D, Zubieta, C, Nanao, M. | Deposit date: | 2016-12-07 | Release date: | 2018-08-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.563 Å) | Cite: | A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily. Sci Rep, 8, 2018
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5MBS
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5MOI
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![BU of 5moi by Molmil](/molmil-images/mine/5moi) | Crystal structure of human IgE-Fc epsilon 3-4 | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ig epsilon chain C region, ... | Authors: | Dore, K.A, Davies, A.M, Drinkwater, N, Beavil, A.J, McDonnell, J.M, Sutton, B.J. | Deposit date: | 2016-12-14 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E. Biochim. Biophys. Acta, 1865, 2017
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5MPE
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![BU of 5mpe by Molmil](/molmil-images/mine/5mpe) | 26S proteasome in presence of ATP (s2) | Descriptor: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN10, ... | Authors: | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | Deposit date: | 2016-12-16 | Release date: | 2017-03-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MPA
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![BU of 5mpa by Molmil](/molmil-images/mine/5mpa) | 26S proteasome in presence of ATP (s2) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | Deposit date: | 2016-12-16 | Release date: | 2017-03-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MRD
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![BU of 5mrd by Molmil](/molmil-images/mine/5mrd) | Human PDK1-PKCiota Kinase Chimera in Complex with Allosteric Compound PS267 Bound to the PIF-Pocket | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Arencibia, J.M, Froehner, W, Krupa, M, Pastor-Flores, D, Merker, P, Oellerich, T, Neimanis, S, Schmithals, C, Koeberle, V, Suess, E, Zeuzem, S, Stark, H, Piiper, A, Odadzic, D, Schulze, J.O, Biondi, R.M. | Deposit date: | 2016-12-22 | Release date: | 2017-01-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms. ACS Chem. Biol., 12, 2017
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5MCP
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![BU of 5mcp by Molmil](/molmil-images/mine/5mcp) | Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION | Authors: | Winter, G, Fernandez-Justel, D, de Pereda, J.M, Revuelta, J.L, Buey, R.M. | Deposit date: | 2016-11-10 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases. Sci Rep, 7, 2017
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5MPC
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![BU of 5mpc by Molmil](/molmil-images/mine/5mpc) | 26S proteasome in presence of BeFx (s4) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | Deposit date: | 2016-12-16 | Release date: | 2017-03-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MVA
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5MOL
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![BU of 5mol by Molmil](/molmil-images/mine/5mol) | Human IgE-Fc crystal structure | Descriptor: | 1,2-ETHANEDIOL, 2-(2-ETHOXYETHOXY)ETHANOL, 2-(2-METHOXYETHOXY)ETHANOL, ... | Authors: | Dore, K.A, Davies, A.M, Drinkwater, N, Beavil, A.J, McDonnell, J.M, Sutton, B.J. | Deposit date: | 2016-12-14 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E. Biochim. Biophys. Acta, 1865, 2017
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5MQ5
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![BU of 5mq5 by Molmil](/molmil-images/mine/5mq5) | A protease-resistant N24S Escherichia coli Asparaginase mutant with outstanding stability and enhanced anti-leukaemic activity | Descriptor: | ASPARTIC ACID, L-asparaginase 2 | Authors: | Maggi, M, Mittelman, S.D, Parmentier, J.H, Whitmire, J.M, Merrell, D.S, Scotti, C. | Deposit date: | 2016-12-20 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro. Sci Rep, 7, 2017
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5MR0
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![BU of 5mr0 by Molmil](/molmil-images/mine/5mr0) | Thermophilic archaeal branched-chain amino acid transaminases from Geoglobus acetivorans and Archaeoglobus fulgidus: biochemical and structural characterisation | Descriptor: | 1,2-ETHANEDIOL, 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, CHLORIDE ION, ... | Authors: | Isupov, M.N, Littlechild, J.A, James, P, Sayer, C, Sutter, J.M, Schmidt, M, Schoenheit, P. | Deposit date: | 2016-12-21 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Thermostable Branched-Chain Amino Acid Transaminases From the ArchaeaGeoglobus acetivoransandArchaeoglobus fulgidus: Biochemical and Structural Characterization. Front Bioeng Biotechnol, 7, 2019
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5M7H
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![BU of 5m7h by Molmil](/molmil-images/mine/5m7h) | Crystal structure of Bacillus subtilis EngA in complex with phosphate ion and GMPPNP | Descriptor: | GTPase Der, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | da Silveira Tome, C, Foucher, A.E, Jault, J.M, Housset, D. | Deposit date: | 2016-10-27 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal structure of Bacillus subtilis EngA in complex with phosphate ion and GMPPNP To Be Published
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5MP9
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![BU of 5mp9 by Molmil](/molmil-images/mine/5mp9) | 26S proteasome in presence of ATP (s1) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | Deposit date: | 2016-12-16 | Release date: | 2017-03-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MLH
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![BU of 5mlh by Molmil](/molmil-images/mine/5mlh) | Plantago Major multifunctional oxidoreductase in complex with 8-oxogeranial and NADP+ | Descriptor: | (2E,6E)-2,6-dimethylocta-2,6-dienedial, CALCIUM ION, GLYCEROL, ... | Authors: | Fellows, R, Russo, C.M, Lee, S.G, Jez, J.M, Chisholm, J.D, Zubieta, C, Nanao, M. | Deposit date: | 2016-12-06 | Release date: | 2018-08-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily. Sci Rep, 8, 2018
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1UDT
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![BU of 1udt by Molmil](/molmil-images/mine/1udt) | Crystal structure of Human Phosphodiesterase 5 complexed with Sildenafil(Viagra) | Descriptor: | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ... | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | Deposit date: | 2003-05-06 | Release date: | 2004-05-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules Nature, 425, 2003
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5MLR
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![BU of 5mlr by Molmil](/molmil-images/mine/5mlr) | Plantago Major multifunctional oxidoreductase V150M mutant in complex with citral and NADP+ | Descriptor: | CHLORIDE ION, Geranaldehyde, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Fellows, R, Russo, C.M, Lee, S.G, Jez, J.M, Chisholm, J.D, Zubieta, C, Nanao, M. | Deposit date: | 2016-12-07 | Release date: | 2018-08-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily. Sci Rep, 8, 2018
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5MQZ
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![BU of 5mqz by Molmil](/molmil-images/mine/5mqz) | Archaeal branched-chain amino acid aminotransferase from Archaeoglobus fulgidus; holoform | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | James, P, Isupov, M.N, Sayer, C, Littlechild, J.A, Sutter, J.M, Schmidt, M, Schoenheit, P. | Deposit date: | 2016-12-21 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Thermostable Branched-Chain Amino Acid Transaminases From the Archaea Geoglobus acetivorans and Archaeoglobus fulgidus : Biochemical and Structural Characterization. Front Bioeng Biotechnol, 7, 2019
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5MVY
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![BU of 5mvy by Molmil](/molmil-images/mine/5mvy) | Thin Filament at low calcium concentration | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Paul, D.M, Squire, J.M, Morris, E.P. | Deposit date: | 2017-01-17 | Release date: | 2018-02-14 | Last modified: | 2018-10-24 | Method: | ELECTRON MICROSCOPY (28.4 Å) | Cite: | Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism. J. Struct. Biol., 197, 2017
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5MU8
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![BU of 5mu8 by Molmil](/molmil-images/mine/5mu8) | HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525 | Descriptor: | Tumor necrosis factor, ~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine | Authors: | Blevitt, J.M, Hack, M.D, Herman, K.L, Jackson, P.F, Krawczuk, P.J, Lebsack, A.D, Liu, A.X, Mirzadegan, T, Nelen, M.I, Patrick, A.P, Steinbacher, S, Milla, M.E, Lumb, K.J. | Deposit date: | 2017-01-12 | Release date: | 2017-03-29 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction. J. Med. Chem., 60, 2017
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2W0C
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![BU of 2w0c by Molmil](/molmil-images/mine/2w0c) | X-ray structure of the entire lipid-containing bacteriophage PM2 | Descriptor: | CALCIUM ION, MAJOR CAPSID PROTEIN P2, PROTEIN 2, ... | Authors: | Abrescia, N.G.A, Grimes, J.M, Kivela, H.M, Assenberg, R, Sutton, G.C, Butcher, S.J, Bamford, J.K.H, Bamford, D.H, Stuart, D.I. | Deposit date: | 2008-08-13 | Release date: | 2008-09-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | Insights Into Virus Evolution and Membrane Biogenesis from the Structure of the Marine Lipid-Containing Bacteriophage Pm2 Mol.Cell, 31, 2008
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1UDU
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![BU of 1udu by Molmil](/molmil-images/mine/1udu) | Crystal structure of Human Phosphodiesterase 5 complexed with tadalafil(Cialis) | Descriptor: | 6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE, MAGNESIUM ION, ZINC ION, ... | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | Deposit date: | 2003-05-06 | Release date: | 2004-05-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules Nature, 425, 2003
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4N6W
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![BU of 4n6w by Molmil](/molmil-images/mine/4n6w) | X-Ray Crystal Structure of Citrate-bound PhnZ | Descriptor: | CITRATE ANION, FE (III) ION, Predicted HD phosphohydrolase PhnZ | Authors: | Worsdorfer, B, Lingaraju, M, Yennawar, N.H, Boal, A.K, Krebs, C, Bollinger Jr, J.M, Pandelia, M.E. | Deposit date: | 2013-10-14 | Release date: | 2013-11-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases. Proc.Natl.Acad.Sci.USA, 110, 2013
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