5MCP

Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP

Summary for 5MCP

• Entry DOI: 10.2210/pdb5mcp/pdb
• Related: 4Z87 5TC3
• Descriptor: Inosine-5'-monophosphate dehydrogenase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: imp dehydrogenase, ashbya gossypii, allosteric modulator, purine nucleotides, oxidoreductase
• Biological source: Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast)
• Cellular location: Cytoplasm : Q756Z6
• Total number of polymer chains: 8
• Total formula weight: 465683.38

Authors

Winter, G.,Fernandez-Justel, D.,de Pereda, J.M.,Revuelta, J.L.,Buey, R.M. (deposition date: 2016-11-10, release date: 2017-06-14, Last modification date: 2024-01-17)

• Primary citation: Buey, R.M.,Fernandez-Justel, D.,Marcos-Alcalde, I.,Winter, G.,Gomez-Puertas, P.,de Pereda, J.M.,Luis Revuelta, J.; A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases.; Sci Rep, 7:2648-2648, 2017; PubMed: 28572600; DOI: 10.1038/s41598-017-02805-x

Experimental method

X-RAY DIFFRACTION (2.4 Å)