5MLM

Plantago Major multifunctional oxidoreductase V150M mutant in complex with progesterone and NADP+

Summary for 5MLM

Entry DOI	10.2210/pdb5mlm/pdb
Descriptor	Progesterone 5-beta-reductase, PROGESTERONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywords	progesterone reductase, iridoid synthase, sdr, enzyme evolution, oxidoreductase
Biological source	Plantago major
Total number of polymer chains	1
Total formula weight	47878.70
Authors	Fellows, R.,Russo, C.M.,Lee, S.G.,Jez, J.M.,Chisholm, J.D.,Zubieta, C.,Nanao, M. (deposition date: 2016-12-07, release date: 2018-08-01, Last modification date: 2024-01-17)
Primary citation	Fellows, R.,Russo, C.M.,Silva, C.S.,Lee, S.G.,Jez, J.M.,Chisholm, J.D.,Zubieta, C.,Nanao, M.H. A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily. Sci Rep, 8:14796-14796, 2018 Cited by PubMed: 30287897 DOI: 10.1038/s41598-018-32967-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.563 Å)

Structure validation