5MLM
Plantago Major multifunctional oxidoreductase V150M mutant in complex with progesterone and NADP+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003854 | molecular_function | 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity |
| A | 0006720 | biological_process | isoprenoid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue STR A 401 |
| Chain | Residue |
| A | LYS147 |
| A | VAL347 |
| A | ILE350 |
| A | PRO351 |
| A | CYS352 |
| A | PRO353 |
| A | HOH505 |
| A | MET150 |
| A | PHE153 |
| A | ILE156 |
| A | ASN205 |
| A | MET215 |
| A | ALA243 |
| A | PHE343 |
| A | ALA346 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | binding site for residue NAP A 402 |
| Chain | Residue |
| A | GLY33 |
| A | VAL34 |
| A | THR35 |
| A | GLY36 |
| A | ILE37 |
| A | ALA62 |
| A | ARG63 |
| A | ARG64 |
| A | CYS80 |
| A | ASP81 |
| A | ILE82 |
| A | VAL104 |
| A | THR105 |
| A | TRP106 |
| A | GLN143 |
| A | THR144 |
| A | TYR179 |
| A | GLY204 |
| A | ILE206 |
| A | SER213 |
| A | MET214 |
| A | MET215 |
| A | HOH503 |
