5MLM
Plantago Major multifunctional oxidoreductase V150M mutant in complex with progesterone and NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Progesterone 5-beta-reductase | polymer | 411 | 46820.8 | 1 | UniProt (D6N9X1) | Plantago major | |
| 2 | B (A) | PROGESTERONE | non-polymer | 314.5 | 1 | Chemie (STR) PubChem (4920) PubChem (5994) PubChem (92940) PubChem (638017) PubChem (657254) PubChem (1274466) PubChem (5320716) PubChem (6576615) PubChem (7048588) PubChem (7059604) PubChem (7059605) PubChem (7059606) PubChem (7092664) PubChem (7092665) PubChem (7092666) PubChem (9948776) PubChem (11869413) PubChem (11869414) PubChem (11869415) PubChem (11876098) PubChem (11876099) PubChem (11876100) PubChem (12303971) PubChem (12303981) PubChem (12303986) PubChem (12303989) PubChem (12303992) PubChem (16219863) PubChem (16401562) PubChem (16757724) PubChem (18635648) PubChem (23615931) PubChem (71200542) PubChem (44135692) PubChem (44275133) PubChem (44279092) PubChem (1807216) PubChem (1807215) PubChem (1807214) PubChem (1201516) PubChem (54269928) PubChem (6603959) PubChem (7004693) PubChem (57526392) PubChem (11869416) PubChem (144033743) PubChem (12303982) PubChem (12303979) PubChem (58483135) PubChem (58766357) PubChem (58872617) PubChem (170068371) PubChem (70865784) PubChem (70987742) PubChem (70987859) PubChem (117072378) PubChem (118670641) PubChem (123410055) PubChem (129010392) PubChem (134688829) PubChem (135189961) PubChem (135190011) PubChem (135249041) PubChem (142168519) PubChem (142402781) PubChem (145130068) PubChem (163070289) PubChem (163070290) PubChem (163070291) PubChem (163070292) | |||
| 3 | C (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 4 | D (A) | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A: 1 - 389 (UniProt: D6N9X1)
| PDB | External Database | Details |
|---|---|---|
| Met -21 | - | initiating methionine |
| Gly -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Tyr -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Ile -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Met 150 | Val 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46820.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1057.9 | |
| All* | Total formula weight | 47878.7 |
