4QYY
| Discovery of Novel, Dual Mechanism ERK Inhibitors by Affinity Selection Screening of an Inactive Kinase State | 分子名称: | (3R)-1-{2-[4-(4-acetylphenyl)piperazin-1-yl]-2-oxoethyl}-N-(3-chloro-4-hydroxyphenyl)pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | Deng, Y, Shipps, G.W, Cooper, A, English, J.M, Annis, D.A, Carr, D, Nan, Y, Wang, T, Zhu, Y.H, Chuang, C, Dayananth, P, Hruza, A.W, Xiao, L, Jin, W, Kirschmeier, P, Windsor, W.T, Samatar, A.A. | 登録日 | 2014-07-26 | 公開日 | 2014-11-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery of Novel, Dual Mechanism ERK Inhibitors by Affinity Selection Screening of an Inactive Kinase. J.Med.Chem., 57, 2014
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4QQV
| Extracellular domains of mouse IL-3 beta receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-3 receptor class 2 subunit beta | 著者 | Jackson, C.J, Young, I.G, Murphy, J.M, Carr, P.D, Ewens, C.L, Dai, J, Ollis, D.L. | 登録日 | 2014-06-30 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Crystal structure of the mouse interleukin-3 beta-receptor: insights into interleukin-3 binding and receptor activation. Biochem.J., 463, 2014
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6Y41
| Fibrinogen-like globe domain of human ANGPTL2 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Angiopoietin-related protein 2, ... | 著者 | Coker, J.A, Krojer, T, Mutisya, J.M, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | 登録日 | 2020-02-19 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Fibrinogen-like globe domain of human ANGPTL2 To Be Published
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6X66
| Legionella pneumophila dDot T4SS OMC | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | 登録日 | 2020-05-27 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
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6XD3
| Structure of the human CAK in complex with THZ1 | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E. | 登録日 | 2020-06-09 | 公開日 | 2020-09-09 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The cryoelectron microscopy structure of the human CDK-activating kinase. Proc.Natl.Acad.Sci.USA, 117, 2020
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6XGQ
| YSD1 bacteriophage capsid | 分子名称: | YSD1_16, YSD1_17 | 著者 | Hardy, J.M, Dunstan, R, Venugopal, H, Lithgow, T.J, Coulibaly, F.J. | 登録日 | 2020-06-17 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The architecture and stabilisation of flagellotropic tailed bacteriophages. Nat Commun, 11, 2020
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4ON0
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6WPW
| GCGR-Gs signaling complex bound to a designed glucagon derivative | 分子名称: | Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Hilger, D, Krishna Kumar, K, Hu, H, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K. | 登録日 | 2020-04-28 | 公開日 | 2020-08-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into differences in G protein activation by family A and family B GPCRs. Science, 369, 2020
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4P2B
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6X2W
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6XZR
| Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | 登録日 | 2020-02-05 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6YBQ
| Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | 著者 | Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. | 登録日 | 2020-03-17 | 公開日 | 2020-10-28 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (1.96 Å) | 主引用文献 | A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation Nat Catal, 2021
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6XZQ
| Influenza C virus polymerase in complex with human ANP32A - Subclass 1 | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | 登録日 | 2020-02-05 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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6Y43
| Fibrinogen-like globe domain of human ANGPTL6 | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Angiopoietin-related protein 6, ... | 著者 | Coker, J.A, Krojer, T, Mutisya, J.M, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | 登録日 | 2020-02-19 | 公開日 | 2020-03-04 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Fibrinogen-like globe domain of human ANGPTL6 To Be Published
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8GDL
| Acid phosphatase pseudoenzyme from flea | 分子名称: | PALMITOLEIC ACID, SEROTONIN, SULFATE ION, ... | 著者 | Lu, S, Andersen, J.F, Ribeiro, J.M. | 登録日 | 2023-03-06 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Acid phosphatase-like proteins, a biogenic amine and leukotriene-binding salivary protein family from the flea Xenopsylla cheopis. Commun Biol, 6, 2023
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4TN0
| Crystal Structure of the C-terminal Periplasmic Domain of Phosphoethanolamine Transferase EptC from Campylobacter jejuni | 分子名称: | UPF0141 protein yjdB, ZINC ION | 著者 | Fage, C.D, Brown, D, Boll, J.M, Keatinge-Clay, A.T, Trent, M.S. | 登録日 | 2014-06-02 | 公開日 | 2014-10-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystallographic study of the phosphoethanolamine transferase EptC required for polymyxin resistance and motility in Campylobacter jejuni. Acta Crystallogr.,Sect.D, 70, 2014
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4RKS
| Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (Mevalonate Bound) | 分子名称: | (R)-MEVALONATE, ACETATE ION, GLYCEROL, ... | 著者 | Vinokur, J.M, Cascio, D, Sawaya, M.R, Bowie, J.U. | 登録日 | 2014-10-13 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases. Protein Sci., 24, 2015
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4RM8
| Crystal structure of human ezrin in space group P21 | 分子名称: | Ezrin | 著者 | Phang, J.M, Harrop, S.J, Davies, R, Duff, A.P, Wilk, K.E, Curmi, P.M.G. | 登録日 | 2014-10-20 | 公開日 | 2015-12-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin. Biochem. J., 473, 2016
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4RO5
| Crystal structure of the SAT domain from the non-reducing fungal polyketide synthase CazM | 分子名称: | GLYCEROL, SAT domain from CazM | 著者 | Winter, J.M, Cascio, D, Sawaya, M.R, Tang, Y. | 登録日 | 2014-10-27 | 公開日 | 2015-09-09 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. J.Am.Chem.Soc., 137, 2015
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6X62
| Legionella pneumophila Dot T4SS OMC | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | 登録日 | 2020-05-27 | 公開日 | 2020-09-30 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
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6X65
| Legionella pneumophila Dot/Icm T4SS | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | 登録日 | 2020-05-27 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife, 9, 2020
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4S1K
| Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 100 K | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyhedrin | 著者 | Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I. | 登録日 | 2015-01-14 | 公開日 | 2015-03-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data. Nat Commun, 6, 2015
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6XBZ
| Structure of the human CDK-activating kinase | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E. | 登録日 | 2020-06-07 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The cryoelectron microscopy structure of the human CDK-activating kinase. Proc.Natl.Acad.Sci.USA, 117, 2020
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6XPK
| CutR Screw, form 1 with 41.9 angstrom pitch | 分子名称: | Ethanolamine utilization protein EutS | 著者 | Ochoa, J.M, Sawaya, M.R, Nguyen, V.N, Duilio, C, Yeates, T.O. | 登録日 | 2020-07-08 | 公開日 | 2020-07-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization. Protein Sci., 29, 2020
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6XGP
| YSD1_17 major capsid protein | 分子名称: | YSD1_17 major capsid protein | 著者 | Grinter, R, Hardy, J.M, Dunstan, R, Lithgow, T.J, Coulibaly, F.J. | 登録日 | 2020-06-17 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The architecture and stabilisation of flagellotropic tailed bacteriophages. Nat Commun, 11, 2020
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