5D8T
 
 | | RNA octamer containing (S)-5' methyl, 2'-F U. | | 分子名称: | COBALT HEXAMMINE(III), RNA oligonucleotide containing (S)-C5'-Me-2'-FU | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2015-08-17 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides.
J.Org.Chem., 81, 2016
|
|
3VEH
 | | Structure of a M. tuberculosis salicylate synthase, MbtI, in complex with an inhibitor methylAMT | | 分子名称: | 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Bulloch, E.M, Chi, G, Manos-Turvey, A, Johnston, J.M, Baker, E.N, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2012-01-08 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis.
Biochemistry, 51, 2012
|
|
4JFB
 | | Crystal structure of OmpF in C2 with tNCS | | 分子名称: | Outer membrane protein F | | 著者 | Wiseman, B, Kilburg, A, Chaptal, V, Reyes-Meija, G.C, Sarwan, J, Falson, P, Jault, J.M. | | 登録日 | 2013-02-28 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.801 Å) | | 主引用文献 | Stubborn contaminants: influence of detergents on the purity of the multidrug ABC transporter BmrA
PLoS ONE, 9, 2014
|
|
8XF7
 | | High-resolution structure of the siderophore periplasmic binding protein FtsB from Streptococcus pyogenes with ferrioxamine E bound | | 分子名称: | (8E)-6,17,28-trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacont-8-ene-2,5,13,16,24,27-hexone, 1,2-ETHANEDIOL, FE (III) ION, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2023-12-13 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes.
Structure, 2024
|
|
4FOF
 | | Crystal Structure of the blue-light absorbing form of the Thermosynechococcus elongatus PixJ GAF-domain | | 分子名称: | Methyl-accepting chemotaxis protein, Phycoviolobilin, blue light-absorbing form, ... | | 著者 | Burgie, E.S, Walker, J.M, Phillips Jr, G.N, Vierstra, R.D. | | 登録日 | 2012-06-20 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.416 Å) | | 主引用文献 | A Photo-Labile Thioether Linkage to Phycoviolobilin Provides the Foundation for the Blue/Green Photocycles in DXCF-Cyanobacteriochromes.
Structure, 21, 2013
|
|
5DIA
 | | PIM1 in complex with Cpd36 ((1S,3S)-N1-(6-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)cyclohexane-1,3-diamine) | | 分子名称: | (1S,3S)-N-{6-[5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridin-3-yl]pyridin-2-yl}cyclohexane-1,3-diamine, Serine/threonine-protein kinase pim-1 | | 著者 | Murray, J.M, Wallweber, H. | | 登録日 | 2015-08-31 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.964 Å) | | 主引用文献 | Discovery of 3,5-substituted 6-azaindazoles as potent pan-Pim inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
|
|
1I2W
 | | BETA-LACTAMASE FROM BACILLUS LICHENIFORMIS BS3 COMPLEXED WITH CEFOXITIN | | 分子名称: | (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, BETA-LACTAMASE, CARBAMIC ACID | | 著者 | Fonze, E, Vanhove, M, Dive, G, Sauvage, E, Frere, J.M, Charlier, P. | | 登録日 | 2001-02-12 | | 公開日 | 2002-03-13 | | 最終更新日 | 2018-09-12 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin
Biochemistry, 41, 2002
|
|
6JSF
 | | Crystal Structure of BACE1 in complex with N-(3-((4S,5S)-2-amino-4-methyl-5-phenyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide | | 分子名称: | Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ... | | 著者 | Fujimoto, K, Matsuoka, E, Asada, N, Tadano, G, Yamamoto, T, Nakahara, K, Fuchino, K, Ito, H, Kanegawa, N, Moechars, D, Gijsen, H.J.M, Kusakabe, K.I. | | 登録日 | 2019-04-08 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-Based Design of Selective beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2.
J.Med.Chem., 62, 2019
|
|
4F2M
 | | Crystal structure of a TGEV coronavirus Spike fragment in complex with the TGEV neutralizing monoclonal antibody 1AF10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | | 著者 | Reguera, J, Santiago, C, Mudgal, G, Ordono, D, Enjuanes, L, Casasnovas, J.M. | | 登録日 | 2012-05-08 | | 公開日 | 2012-08-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.
Plos Pathog., 8, 2012
|
|
8XET
 | | High-resolution structure of the siderophore periplasmic binding protein FtsB from Streptococcus pyogenes | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2023-12-13 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.11 Å) | | 主引用文献 | Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes.
Structure, 2024
|
|
8XFA
 | | Structure of the siderophore periplasmic binding protein FtsB mutant Y137A from Streptococcus pyogenes with ferrioxamine E bound | | 分子名称: | (8E)-6,17,28-trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacont-8-ene-2,5,13,16,24,27-hexone, FE (III) ION, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2023-12-13 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes.
Structure, 2024
|
|
8XFI
 | | High-resolution structure of the siderophore periplasmic binding protein FtsB from Streptococcus pyogenes with ferrioxamine E bound (crystal form 2) | | 分子名称: | (8E)-6,17,28-trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacont-8-ene-2,5,13,16,24,27-hexone, CHLORIDE ION, FE (III) ION, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2023-12-13 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes.
Structure, 2024
|
|
8XEU
 | |
8XF9
 | | High-resolution structure of the siderophore periplasmic binding protein FtsB mutant Y137A from Streptococcus pyogenes | | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2023-12-13 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes.
Structure, 2024
|
|
4FGZ
 | | Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine | | 分子名称: | 4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL, PHOSPHATE ION, Phosphoethanolamine N-methyltransferase, ... | | 著者 | Lee, S.G, Alpert, T.D, Jez, J.M. | | 登録日 | 2012-06-05 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | | 主引用文献 | Crystal structure of phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with amodiaquine.
Bioorg.Med.Chem.Lett., 22, 2012
|
|
8XF4
 | | Structure of the siderophore periplasmic binding protein FtsB from Streptococcus pyogenes with Bisucaberin bound | | 分子名称: | 1,12-bis(oxidanyl)-1,6,12,17-tetrazacyclodocosane-2,5,13,16-tetrone, FE (III) ION, Iron-hydroxamate ABC transporter substrate-binding protein FtsB | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2023-12-13 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes.
Structure, 2024
|
|
8XF8
 | | High-resolution structure of the siderophore periplasmic binding protein FtsB from Streptococcus pyogenes with ferrioxamine B | | 分子名称: | 1,2-ETHANEDIOL, Ferrioxamine B, Iron-hydroxamate ABC transporter substrate-binding protein FtsB, ... | | 著者 | Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. | | 登録日 | 2023-12-13 | | 公開日 | 2024-10-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes.
Structure, 2024
|
|
1NIN
 | | PLASTOCYANIN FROM ANABAENA VARIABILIS, NMR, 20 STRUCTURES | | 分子名称: | COPPER (II) ION, PLASTOCYANIN | | 著者 | Badsberg, U, Jorgensen, A.M.M, Gesmar, H, Led, J.J, Hammerstad-Petersen, J.M, Ulstrup, J. | | 登録日 | 1996-03-13 | | 公開日 | 1996-10-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of reduced plastocyanin from the blue-green alga Anabaena variabilis.
Biochemistry, 35, 1996
|
|
3VC3
 | |
1HI1
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2001-01-01 | | 公開日 | 2001-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
|
|
3QCQ
 | | Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-(3-Amino-1H-indazol-6-yl)-N4-ethyl-2,4-pyrimidinediamine | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, 6-(3-amino-2H-indazol-6-yl)-N~4~-ethylpyrimidine-2,4-diamine, GLYCEROL, ... | | 著者 | Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M. | | 登録日 | 2011-01-17 | | 公開日 | 2011-03-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors.
J.Med.Chem., 54, 2011
|
|
4GL9
 | | Crystal structure of inhibitory protein SOCS3 in complex with JAK2 kinase domain and fragment of GP130 intracellular domain | | 分子名称: | 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Interleukin-6 receptor subunit beta, PHOSPHATE ION, ... | | 著者 | Kershaw, N.J, Murphy, J.M, Laktyushin, A, Nicola, N.A, Babon, J.J. | | 登録日 | 2012-08-14 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
Nat.Struct.Mol.Biol., 20, 2013
|
|
3VIC
 | | Green-fluorescent variant of the non-fluorescent chromoprotein Rtms5 | | 分子名称: | CHLORIDE ION, GFP-like non-fluorescent chromoprotein, IODIDE ION | | 著者 | Battad, J.M, Traore, D.A.K, Byres, E, Wilce, M, Devenish, R.J, Rossjohn, J, Prescott, M. | | 登録日 | 2011-09-28 | | 公開日 | 2012-06-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A Green Fluorescent Protein Containing a QFG Tri-Peptide Chromophore: Optical Properties and X-Ray Crystal Structure.
Plos One, 7, 2012
|
|
1NJO
 | | The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed with a short substrate analog ACCPuromycin (ACCP) | | 分子名称: | 23S ribosomal RNA, RNA ACC(Puromycin) | | 著者 | Bashan, A, Agmon, I, Zarivatch, R, Schluenzen, F, Harms, J.M, Berisio, R, Bartels, H, Hansen, H.A, Yonath, A. | | 登録日 | 2003-01-02 | | 公開日 | 2003-02-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural basis of the ribosomal machinery for Peptide bond formation,
translocation, and nascent chain progression
Mol.Cell, 11, 2003
|
|
6WTW
 | | Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate | | 分子名称: | DASS family sodium-coupled anion symporter | | 著者 | Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) | | 登録日 | 2020-05-04 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
|
|
