3RIT
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![BU of 3rit by Molmil](/molmil-images/mine/3rit) | Crystal structure of Dipeptide Epimerase from Methylococcus capsulatus complexed with Mg and dipeptide L-Arg-D-Lys | 分子名称: | ARGININE, D-LYSINE, Dipeptide epimerase, ... | 著者 | Lukk, T, Sakai, A, Song, L, Gerlt, J.A, Nair, S.K. | 登録日 | 2011-04-14 | 公開日 | 2011-04-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
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4C68
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![BU of 4c68 by Molmil](/molmil-images/mine/4c68) | Plasmodium vivax N-myristoyltransferase in complex with a peptidomimetic inhibitor | 分子名称: | 2-oxopentadecyl-CoA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Olaleye, T.O, Brannigan, J.A, Goncalves, V, Roberts, S.M, Leatherbarrow, R.J, Wilkinson, A.J, Tate, E.W. | 登録日 | 2013-09-17 | 公開日 | 2014-09-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Peptidomimetic Inhibitors of N-Myristoyltransferase from Human Malaria and Leishmaniasis Parasites. Org.Biomol.Chem., 12, 2014
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1Q99
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![BU of 1q99 by Molmil](/molmil-images/mine/1q99) | Crystal structure of the Saccharomyces cerevisiae SR protein kinsae, Sky1p, complexed with the non-hydrolyzable ATP analogue, AMP-PNP | 分子名称: | 1,2-ETHANEDIOL, METHANOL, NICKEL (II) ION, ... | 著者 | Nolen, B, Ngo, J, Chakrabarti, S, Vu, D, Adams, J.A, Ghosh, G. | 登録日 | 2003-08-22 | 公開日 | 2003-09-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Nucleotide-Induced Conformational Changes in the Saccharomyces cerevisiae SR Protein Kinase, Sky1p, Revealed by X-ray Crystallography Biochemistry, 42, 2003
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4CMP
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![BU of 4cmp by Molmil](/molmil-images/mine/4cmp) | Crystal structure of S. pyogenes Cas9 | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | 登録日 | 2014-01-16 | 公開日 | 2014-02-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation. Science, 343, 2014
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4D0Y
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3O6G
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![BU of 3o6g by Molmil](/molmil-images/mine/3o6g) | Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator | 分子名称: | 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutamate receptor 2, ... | 著者 | Maclean, J.K.F, Campbell, R.A, Cumming, I.A, Gillen, K.J, Gillespie, J, Jamieson, C, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Martin, F, Moir, E.M, Morrow, J.A, Pantling, J, Rankovic, Z, Smith, L. | 登録日 | 2010-07-29 | 公開日 | 2010-09-15 | 最終更新日 | 2017-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A novel series of positive modulators of the AMPA receptor: structure-based lead optimization. Bioorg.Med.Chem.Lett., 20, 2010
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1QVK
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![BU of 1qvk by Molmil](/molmil-images/mine/1qvk) | Structure of the antimicrobial hexapeptide cyc-(RRWWRF) bound to DPC micelles | 分子名称: | c-RW | 著者 | Appelt, C, Soderhall, J.A, Bienert, M, Dathe, M, Schmieder, P. | 登録日 | 2003-08-28 | 公開日 | 2004-09-28 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Antimicrobial, Cationic Hexapeptide Cyclo(RRWWRF) and Its Analogues in Solution and Bound to Detergent Micelles Chembiochem, 6, 2005
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1QVN
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![BU of 1qvn by Molmil](/molmil-images/mine/1qvn) | Structure of SP4160 Bound to IL-2 V69A | 分子名称: | 2-GUANIDINO-4-METHYL-PENTANOIC ACID [2-(4-{5-[4-(4-ACETYLAMINO-BENZYLOXY)-2,3-DICHLORO-PHENYL]-2-METHYL-2H-PYRAZOL-3-YL}-PIPERIDIN-1-YL)-2-OXO-ETHYL]-AMIDE, Interleukin-2, ZINC ION | 著者 | Thanos, C.D, Delano, W.L, Wells, J.A. | 登録日 | 2003-08-28 | 公開日 | 2005-04-05 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Hot-spot mimicry of a cytokine receptor by a small molecule. Proc.Natl.Acad.Sci.USA, 103, 2006
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1QGD
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4CIC
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![BU of 4cic by Molmil](/molmil-images/mine/4cic) | T. potens IscR | 分子名称: | HEXA-ALANINE PEPTIDE, SODIUM ION, TRANSCRIPTIONAL REGULATOR, ... | 著者 | Santos, J.A, Macedo-Ribeiro, S, Pereira, P.J.B. | 登録日 | 2013-12-06 | 公開日 | 2014-05-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Unique Regulation of Iron-Sulfur Cluster Biogenesis in a Gram-Positive Bacterium. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CVD
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1SOS
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![BU of 1sos by Molmil](/molmil-images/mine/1sos) | ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE, ... | 著者 | Parge, H.E, Hallewell, R.A, Tainer, J.A. | 登録日 | 1992-02-11 | 公開日 | 1993-04-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase. Proc.Natl.Acad.Sci.USA, 89, 1992
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4DEX
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![BU of 4dex by Molmil](/molmil-images/mine/4dex) | |
4DFA
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![BU of 4dfa by Molmil](/molmil-images/mine/4dfa) | Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/L36A at cryogenic temperature | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | 著者 | Caro, J.A, Clark, I.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | 登録日 | 2012-01-23 | 公開日 | 2012-02-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.404 Å) | 主引用文献 | Pressure effects in proteins To be Published
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4DGZ
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![BU of 4dgz by Molmil](/molmil-images/mine/4dgz) | Crystal structure of Staphylococcal nuclease variant Delta+PHS I92A/L125A at cryogenic temperature | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | 著者 | Caro, J.A, Nam, S.P, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | 登録日 | 2012-01-27 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Pressure effects in proteins To be Published
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4DX7
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![BU of 4dx7 by Molmil](/molmil-images/mine/4dx7) | Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop | 分子名称: | Acriflavine resistance protein B, DARPIN, DECANE, ... | 著者 | Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. | 登録日 | 2012-02-27 | 公開日 | 2012-05-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.253 Å) | 主引用文献 | Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc.Natl.Acad.Sci.USA, 109, 2012
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1SJA
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![BU of 1sja by Molmil](/molmil-images/mine/1sja) | X-ray structure of o-Succinylbenzoate Synthase complexed with N-acetylmethionine | 分子名称: | MAGNESIUM ION, N-ACETYLMETHIONINE, N-acylamino acid racemase | 著者 | Thoden, J.B, Taylor-Ringia, E.A, Garrett, J.B, Gerlt, J.A, Holden, H.M, Rayment, I. | 登録日 | 2004-03-03 | 公開日 | 2004-06-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis Biochemistry, 43, 2004
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4DF0
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![BU of 4df0 by Molmil](/molmil-images/mine/4df0) | Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus | 分子名称: | CHLORIDE ION, NICKEL (II) ION, Orotidine 5'-phosphate decarboxylase, ... | 著者 | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | 登録日 | 2012-01-22 | 公開日 | 2013-01-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus To be Published
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1SO5
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![BU of 1so5 by Molmil](/molmil-images/mine/1so5) | Crystal structure of E112Q mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate | 分子名称: | 3-keto-L-gulonate 6-phosphate decarboxylase, L-THREONOHYDROXAMATE 4-PHOSPHATE, MAGNESIUM ION | 著者 | Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I. | 登録日 | 2004-03-12 | 公開日 | 2004-06-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Evolution of Enzymatic Activities in the Orotidine 5'-Monophosphate Decarboxylase Suprafamily: Crystallographic Evidence for a Proton Relay System in the Active Site of 3-Keto-l-gulonate 6-Phosphate Decarboxylase(,) Biochemistry, 43, 2004
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3RGT
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![BU of 3rgt by Molmil](/molmil-images/mine/3rgt) | Crystal structure of d-mannonate dehydratase from Chromohalobacter salexigens complexed with D-Arabinohydroxamate | 分子名称: | (2S,3R,4R)-2,3,4,5-tetrahydroxy-N-oxo-pentanamide, COBALT (II) ION, D-mannonate dehydratase | 著者 | Fedorov, A.A, Fedorov, E.V, Wichelecki, D, Gerlt, J.A, Almo, S.C. | 登録日 | 2011-04-09 | 公開日 | 2012-04-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of d-mannonate dehydratase from Chromohalobacter salexigens complexed with d-arabinohydroxamate To be Published
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4DO7
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![BU of 4do7 by Molmil](/molmil-images/mine/4do7) | Crystal structure of an amidohydrolase (cog3618) from burkholderia multivorans (target efi-500235) with bound zn, space group c2 | 分子名称: | Amidohydrolase 2, SULFATE ION, ZINC ION | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Seidel, R.D, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Al Obaidi, N.F, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Raushel, F.M, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-02-09 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of an amidohydrolase (cog3618) from burkholderia multivorans (target efi-500235) with bound zn, space group c2 to be published
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1SF2
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![BU of 1sf2 by Molmil](/molmil-images/mine/1sf2) | Structure of E. coli gamma-aminobutyrate aminotransferase | 分子名称: | 1,2-ETHANEDIOL, 4-aminobutyrate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Liu, W, Peterson, P.E, Carter, R.J, Zhou, X, Langston, J.A, Fisher, A.J, Toney, M.D. | 登録日 | 2004-02-19 | 公開日 | 2004-09-14 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase. Biochemistry, 43, 2004
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3R0K
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![BU of 3r0k by Molmil](/molmil-images/mine/3r0k) | Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Tartrate bound, no Mg | 分子名称: | D(-)-TARTARIC ACID, Enzyme of enolase superfamily, GLYCEROL, ... | 著者 | Vetting, M.W, Hillerich, B, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2011-03-08 | 公開日 | 2011-03-30 | 最終更新日 | 2012-03-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
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1SL3
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![BU of 1sl3 by Molmil](/molmil-images/mine/1sl3) | crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor | 分子名称: | (2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-2-OXOPYRAZIN-1(2H)-YL]-N-[5-CHLORO-2-(1H-TETRAZOL-1-YL)BENZYL]ACETAMIDE, Hirudin, thrombin | 著者 | Young, M.B, Barrow, J.C, Glass, K.L, Lundell, G.F, Newton, C.L, Pellicore, J.M, Rittle, K.E, Selnick, H.G, Stauffer, K.J, Vacca, J.P, Williams, P.D, Bohn, D, Clayton, F.C, Cook, J.J, Krueger, J.A, Kuo, L.C, Lewis, S.D, Lucas, B.J, McMasters, D.R, Miller-Stein, C, Pietrak, B.L. | 登録日 | 2004-03-05 | 公開日 | 2004-08-03 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors J.Med.Chem., 47, 2004
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4DF7
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![BU of 4df7 by Molmil](/molmil-images/mine/4df7) | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23L/V99I at cryogenic temperature | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | 著者 | Caro, J.A, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | 登録日 | 2012-01-23 | 公開日 | 2012-02-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Pressure effects in proteins To be Published
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