4DEX

Crystal structure of the Voltage Dependent Calcium Channel beta-2 Subunit in Complex With The CaV2.2 I-II Linker.

Summary for 4DEX

Entry DOI	10.2210/pdb4dex/pdb
Related	1t3l 4DEY
Descriptor	Voltage-dependent L-type calcium channel subunit beta-2, Voltage-dependent N-type calcium channel subunit alpha-1B (3 entities in total)
Functional Keywords	maguk, voltage dependent calcium channel, transport protein
Biological source	Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits) More
Cellular location	Cell membrane, sarcolemma ; Peripheral membrane protein ; Cytoplasmic side : P54288 Membrane; Multi-pass membrane protein: Q02294
Total number of polymer chains	2
Total formula weight	51543.75
Authors	Almagor, L.,Hirsch, J.A. (deposition date: 2012-01-22, release date: 2012-06-13, Last modification date: 2024-02-28)
Primary citation	Almagor, L.,Chomsky-Hecht, O.,Ben-Mocha, A.,Hendin-Barak, D.,Dascal, N.,Hirsch, J.A. The role of a voltage-dependent Ca2+ channel intracellular linker: a structure-function analysis. J.Neurosci., 32:7602-7613, 2012 Cited by PubMed: 22649239 DOI: 10.1523/JNEUROSCI.5727-11.2012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation