4DEX

Crystal structure of the Voltage Dependent Calcium Channel beta-2 Subunit in Complex With The CaV2.2 I-II Linker.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Voltage-dependent L-type calcium channel subunit beta-2	polymer	339	38425.0	1	UniProt (P54288) Pfam (PF12052) Pfam (PF00625)	Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits)	CAB2, Calcium channel voltage-dependent subunit beta 2
2	B (B)	Voltage-dependent N-type calcium channel subunit alpha-1B	polymer	113	13118.8	1	UniProt (Q02294)	Rattus norvegicus (brown rat rat rats)	Brain calcium channel III, BIII, Calcium channel, L type, alpha-1 polypeptide isoform 5, Voltage-gated calcium channel subunit alpha Cav2.2
3	C, D (A, B)	water	water		18.0	162	Chemie (HOH)

Sequence modifications

A: 25 - 137 (UniProt: P54288)
A: 203 - 422 (UniProt: P54288)

PDB	External Database	Details
Glu 138	-	SEE REMARK 999
Phe 139	-	SEE REMARK 999
Lys 140	-	SEE REMARK 999
Leu 141	-	SEE REMARK 999

B: 358 - 468 (UniProt: Q02294)

PDB	External Database	Details
Gly 356	-	expression tag
Ser 357	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51543.8
All*	Total formula weight	51543.8

*Water molecules are not included.