4OMN
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1I1G
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![BU of 1i1g by Molmil](/molmil-images/mine/1i1g) | CRYSTAL STRUCTURE OF THE LRP-LIKE TRANSCRIPTIONAL REGULATOR FROM THE ARCHAEON PYROCOCCUS FURIOSUS | Descriptor: | TRANSCRIPTIONAL REGULATOR LRPA | Authors: | Leonard, P.M, Smits, S.H.J, Sedelnikova, S.E, Brinkman, A.B, de Vos, W.M, van der Oost, J, Rice, D.W, Rafferty, J.B. | Deposit date: | 2001-02-01 | Release date: | 2002-02-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus. EMBO J., 20, 2001
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8YM7
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![BU of 8ym7 by Molmil](/molmil-images/mine/8ym7) | Crystal structure of Lysine Specific Demethylase 1 (LSD1) with JH-45 | Descriptor: | 4-[5-(4-azanylpiperidin-1-yl)-8-(4-methylphenyl)pyrido[3,4-b]pyrazin-7-yl]-2-fluoranyl-benzenecarbonitrile, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ... | Authors: | Zhiyan, D, Danyan, C, Hong, J, Tongchao, L, Bing, X. | Deposit date: | 2024-03-08 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Discovery of Novel LSD1 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease To Be Published
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7YKH
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![BU of 7ykh by Molmil](/molmil-images/mine/7ykh) | Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR2 peptide | Descriptor: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | Authors: | Zhang, M, Lin, L, Zhu, J. | Deposit date: | 2022-07-22 | Release date: | 2023-08-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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4OMQ
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5HNS
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![BU of 5hns by Molmil](/molmil-images/mine/5hns) | Structure of glycosylated NPC1 luminal domain C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Niemann-Pick C1 protein, ... | Authors: | Zhao, Y, Ren, J, Harlos, K, Stuart, D.I. | Deposit date: | 2016-01-18 | Release date: | 2016-02-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions. Febs Lett., 590, 2016
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5ABH
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![BU of 5abh by Molmil](/molmil-images/mine/5abh) | Structure of GH84 with ligand | Descriptor: | 1,2-ETHANEDIOL, 2-[(2R,3S,4R,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-pentyl-pyrrolidin-2-yl]-N-methyl-ethanamide, CALCIUM ION, ... | Authors: | Bergeron-Brlek, M, Goodwin-Tindall, J, Cekic, N, Varghese, V, Zandberg, W.F, Shan, X, Roth, C, Chan, S, Davies, G.J, Vocadlo, D.J, Britton, R. | Deposit date: | 2015-08-05 | Release date: | 2015-11-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable Oga Inhibitors. Angew.Chem.Int.Ed.Engl., 54, 2015
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8H4H
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5HUM
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![BU of 5hum by Molmil](/molmil-images/mine/5hum) | The crystal structure of neuraminidase from A/Sichuan/26221/2014 influenza virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, neuraminidase | Authors: | Yang, H, Carney, P.J, Guo, Z, Chang, J.C, Stevens, J. | Deposit date: | 2016-01-27 | Release date: | 2016-04-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular Characterizations of Surface Proteins Hemagglutinin and Neuraminidase from Recent H5Nx Avian Influenza Viruses. J.Virol., 90, 2016
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5A8J
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![BU of 5a8j by Molmil](/molmil-images/mine/5a8j) | Crystal structure of the ArnB paralog VWA2 from Sulfolobus acidocaldarius | Descriptor: | CHLORIDE ION, CITRIC ACID, GLYCEROL, ... | Authors: | Hoffmann, L, Anders, K, Reimann, J, Linne, U, Essen, L.-O, Albers, S.-V. | Deposit date: | 2015-07-16 | Release date: | 2016-06-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Phosphorylation-Dependent Interaction between an Archaeal Von Willebrand and Fha Domain Recruits Arna-Arnb Complex to DNA for Repression of Motility To be Published
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5HOT
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![BU of 5hot by Molmil](/molmil-images/mine/5hot) | Structural Basis for Inhibitor-Induced Aggregation of HIV-1 Integrase | Descriptor: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, Integrase | Authors: | Gupta, K, Turkki, V, Sherrill-Mix, S, Hwang, Y, Eilers, G, Taylor, L, McDanal, C, Wang, P, Temelkoff, D, Nolte, R, Velthuisen, E, Jeffrey, J, Van Duyne, G.D, Bushman, F.D. | Deposit date: | 2016-01-19 | Release date: | 2016-12-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
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8H61
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![BU of 8h61 by Molmil](/molmil-images/mine/8h61) | Ketoreductase CpKR mutant - M2 | Descriptor: | Mutant M2 of ketoreductase CpKR, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Chen, C, Pan, J, Xu, J.H. | Deposit date: | 2022-10-14 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Computational redesign of a robust ketoreductase for asymmetric synthesis of enantiopure diltiazem precursor. To Be Published
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1EYX
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![BU of 1eyx by Molmil](/molmil-images/mine/1eyx) | CRYSTAL STRUCTURE OF R-PHYCOERYTHRIN AT 2.2 ANGSTROMS | Descriptor: | BILIVERDINE IX ALPHA, PHYCOCYANOBILIN, PHYCOUROBILIN, ... | Authors: | Contreras-Martel, C, Legrand, P, Piras, C, Vernede, X, Martinez-Oyanedel, J, Bunster, M, Fontecilla-Camps, J.C. | Deposit date: | 2000-05-09 | Release date: | 2000-11-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystallization and 2.2 A resolution structure of R-phycoerythrin from Gracilaria chilensis: a case of perfect hemihedral twinning. Acta Crystallogr.,Sect.D, 57, 2001
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5HWO
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![BU of 5hwo by Molmil](/molmil-images/mine/5hwo) | MvaS in complex with 3-hydroxy-3-methylglutaryl coenzyme A | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | Authors: | Bock, T, Kasten, J, Blankenfeldt, W. | Deposit date: | 2016-01-29 | Release date: | 2016-05-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem, 17, 2016
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8H4R
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![BU of 8h4r by Molmil](/molmil-images/mine/8h4r) | The Crystal Structure of CDK3 and CyclinE1 Complex with Dinaciclib from Biortus | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, G1/S-specific cyclin-E1, ... | Authors: | Gui, W, Wang, F, Cheng, W, Gao, J, Huang, Y, Ouyang, Z. | Deposit date: | 2022-10-11 | Release date: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The Crystal Structure of CDK3 and CyclinE1 Complex with Dinaciclib from Biortus To Be Published
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5HXZ
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![BU of 5hxz by Molmil](/molmil-images/mine/5hxz) | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, CHLORIDE ION, ... | Authors: | Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. | Deposit date: | 2016-01-31 | Release date: | 2017-02-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
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1I5L
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![BU of 1i5l by Molmil](/molmil-images/mine/1i5l) | CRYSTAL STRUCTURE OF AN SM-LIKE PROTEIN (AF-SM1) FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH SHORT POLY-U RNA | Descriptor: | 5'-R(*UP*UP*U)-3', PUTATIVE SNRNP SM-LIKE PROTEIN AF-SM1, URIDINE | Authors: | Toro, I, Thore, S, Mayer, C, Basquin, J, Seraphin, B, Suck, D. | Deposit date: | 2001-02-28 | Release date: | 2001-08-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | RNA binding in an Sm core domain: X-ray structure and functional analysis of an archaeal Sm protein complex. EMBO J., 20, 2001
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1SAX
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![BU of 1sax by Molmil](/molmil-images/mine/1sax) | Three-dimensional structure of s.aureus methicillin-resistance regulating transcriptional repressor meci in complex with 25-bp ds-DNA | Descriptor: | 5'-d(CAAAATTACAACTGTAATATCGGAG)-3', 5'-d(GCTCCGATATTACAGTTGTAATTTT)-3', Methicillin resistance regulatory protein mecI, ... | Authors: | Garcia-Castellanos, R, Mallorqui-Fernandez, G, Marrero, A, Potempa, J, Coll, M, Gomis-Ruth, F.X. | Deposit date: | 2004-02-09 | Release date: | 2004-04-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator J.Biol.Chem., 279, 2004
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5HYE
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![BU of 5hye by Molmil](/molmil-images/mine/5hye) | Glycosylated Knob-Knob Fc fragment (P212121) | Descriptor: | Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Kuglstatter, A, Stihle, M, Benz, J. | Deposit date: | 2016-02-01 | Release date: | 2017-02-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural differences between glycosylated, disulfide-linked heterodimeric Knob-into-Hole Fc fragment and its homodimeric Knob-Knob and Hole-Hole side products. Protein Eng. Des. Sel., 30, 2017
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5ANN
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![BU of 5ann by Molmil](/molmil-images/mine/5ann) | Structure of fructofuranosidase from Xanthophyllomyces dendrorhous | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-FRUCTOFURANOSIDASE, ... | Authors: | Ramirez-Escudero, M, Sanz-Aparicio, J. | Deposit date: | 2015-09-07 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural Analysis of Beta-Fructofuranosidase from Xanthophyllomyces Dendrorhous Reveals Unique Features and the Crucial Role of N-Glycosylation in Oligomerization and Activity J.Biol.Chem., 291, 2016
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1EBR
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1EBS
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5HZ2
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![BU of 5hz2 by Molmil](/molmil-images/mine/5hz2) | Crystal structure of PhaC1 from Ralstonia eutropha | Descriptor: | GLYCEROL, Poly-beta-hydroxybutyrate polymerase, SULFATE ION | Authors: | Kim, J, Kim, K.-J. | Deposit date: | 2016-02-02 | Release date: | 2016-12-07 | Last modified: | 2017-04-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Ralstonia eutropha polyhydroxyalkanoate synthase C-terminal domain and reaction mechanisms. Biotechnol J, 12, 2017
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8HLG
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![BU of 8hlg by Molmil](/molmil-images/mine/8hlg) | Crystal structure of MoaE | Descriptor: | Molybdenum cofactor biosynthesis protein D/E, SULFATE ION | Authors: | Cai, J, Zhao, Y. | Deposit date: | 2022-11-30 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | MoaE Is Involved in Response to Oxidative Stress in Deinococcus radiodurans. Int J Mol Sci, 24, 2023
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1S6R
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![BU of 1s6r by Molmil](/molmil-images/mine/1s6r) | 908R class c beta-lactamase bound to iodo-acetamido-phenyl boronic acid | Descriptor: | 4-IODO-ACETAMIDO PHENYLBORONIC ACID, beta-lactamase | Authors: | Wouters, J. | Deposit date: | 2004-01-27 | Release date: | 2004-02-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogue. Cell.Mol.Life Sci., 60, 2003
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