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8YM7

Crystal structure of Lysine Specific Demethylase 1 (LSD1) with JH-45

This is a non-PDB format compatible entry.
Summary for 8YM7
Entry DOI10.2210/pdb8ym7/pdb
DescriptorLysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywordslsd1, flavoprotein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight90118.66
Authors
Zhiyan, D.,Danyan, C.,Hong, J.,Tongchao, L.,Bing, X. (deposition date: 2024-03-08, release date: 2024-05-22)
Primary citationJiang, H.,Tongchao, L.,Bing, X.,Zhiyan, D.,Danyan, C.
Discovery of Novel LSD1 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.83 Å)
Structure validation

221051

PDB entries from 2024-06-12

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