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PDB: 42745 results

7UK1
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Complex Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) with Murine Virus-like 30S Transcript-1 (VS30-1) Reveals Cooperative Binding of RNA
Descriptor: MAGNESIUM ION, Splicing factor, proline- and glutamine-rich
Authors:Lomakin, I.B, Wang, J.
Deposit date:2022-03-31
Release date:2022-09-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1.
Biochemistry, 61, 2022
8K4W
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Structure of a triple-helix region of human collagen type I from Trautec
Descriptor: CHLORIDE ION, triple-helix region of human collagen type I
Authors:Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S.
Deposit date:2023-07-20
Release date:2023-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a triple-helix region of human collagen type I from Trautec.
To Be Published
8TLR
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BU of 8tlr by Molmil
Crystal Structure of human HRAS G12C covalently bound to AMG 510
Descriptor: AMG 510 (bound form), GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Morstein, J, Guiley, K.Z, Shokat, K.M.
Deposit date:2023-07-27
Release date:2024-07-31
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (1.70003951 Å)
Cite:Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket.
Cell, 2024
8TRQ
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BU of 8trq by Molmil
T cell recognition of citrullinated vimentin peptide presented by HLA-DR4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A07 TCR alpha chain, A07 TCR beta chain, ...
Authors:Loh, T.J, Lim, J.J, Reid, H.H, Rossjohn, J.
Deposit date:2023-08-10
Release date:2024-07-31
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4.
Nat Commun, 15, 2024
1C12
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BU of 1c12 by Molmil
INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE
Descriptor: PROTEIN (ANTIBODY FRAGMENT FAB), TRAZEOLIDE
Authors:Langedijk, A.C, Spinelli, S, Anguille, C, Hermans, P, Nederlof, J, Butenandt, J, Honegger, A, Cambillau, C, Pluckthun, A.
Deposit date:1999-07-20
Release date:1999-08-14
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insight into odorant perception: the crystal structure and binding characteristics of antibody fragments directed against the musk odorant traseolide.
J.Mol.Biol., 292, 1999
5K5W
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BU of 5k5w by Molmil
Crystal structure of limiting CO2-inducible protein LCIB
Descriptor: ZINC ION, limiting CO2-inducible protein LCIB
Authors:Jin, S, Sun, J, Wunder, T, Tang, D, Mueller-Cajar, O.M, Gao, Y.
Deposit date:2016-05-24
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.591 Å)
Cite:Structural insights into the LCIB protein family reveals a new group of beta-carbonic anhydrases
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
8TRL
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BU of 8trl by Molmil
T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lim, J.J, Loh, T.J, Reid, H.H, Rossjohn, J.
Deposit date:2023-08-09
Release date:2024-07-31
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4.
Nat Commun, 15, 2024
8OE5
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BU of 8oe5 by Molmil
Structure of P167S BlaC from Mycobacterium tuberculosis at pH 6.3
Descriptor: Beta-lactamase, CITRATE ANION, GLYCEROL
Authors:Sun, J, Chikunova, A, Ubbink, M.
Deposit date:2023-03-10
Release date:2023-08-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
8DS0
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BU of 8ds0 by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp14-nsp15 (C14) cut site sequence (form 2)
Descriptor: 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER
Authors:Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
Deposit date:2022-07-21
Release date:2022-09-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8OE1
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Structure of P167S BlaC from Mycobacterium tuberculosis at pH 5
Descriptor: Beta-lactamase, GLYCEROL
Authors:Sun, J, Chikunova, A, Ubbink, M.
Deposit date:2023-03-10
Release date:2023-08-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
8TRR
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BU of 8trr by Molmil
T cell recognition of citrullinated vimentin peptide presented by HLA-DR4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Loh, T.J, Lim, J.J, Reid, H.H, Rossjohn, J.
Deposit date:2023-08-10
Release date:2024-07-31
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4.
Nat Commun, 15, 2024
8DRZ
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BU of 8drz by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp13-nsp14 (C13) cut site sequence
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
Deposit date:2022-07-21
Release date:2022-09-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
7UY7
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BU of 7uy7 by Molmil
Tetrahymena CST with Polymerase alpha-Primase
Descriptor: DNA polymerase, Telomerase associated protein p50, Telomerase-associated protein of 19 kDa, ...
Authors:He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
8U9J
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BU of 8u9j by Molmil
The crystal structure of iron-bound human ADO C18S C239S variant at 2.02 Angstrom
Descriptor: 2-aminoethanethiol dioxygenase, FE (III) ION, GLYCEROL, ...
Authors:Liu, A, Li, J, Duan, R.
Deposit date:2023-09-19
Release date:2024-07-17
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Cobalt(II)-Substituted Cysteamine Dioxygenase Oxygenation Proceeds through a Cobalt(III)-Superoxo Complex.
J.Am.Chem.Soc., 146, 2024
8DS2
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BU of 8ds2 by Molmil
Structure of SARS-CoV-2 Mpro in complex with the nsp13-nsp14 (C13) cut site sequence (form 2)
Descriptor: 3C-like proteinase nsp5, GLYCEROL, SODIUM ION
Authors:Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
Deposit date:2022-07-21
Release date:2022-09-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
7UY5
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BU of 7uy5 by Molmil
Tetrahymena telomerase with CST
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
4HVZ
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BU of 4hvz by Molmil
Crystal structure of brucella abortus immunogenic BP26 protein
Descriptor: 26 kDa periplasmic immunogenic protein
Authors:Kim, D, Park, J, Oh, B, Song, J.
Deposit date:2012-11-07
Release date:2013-01-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Brucella Immunogenic BP26 Forms a Channel-like Structure.
J.Mol.Biol., 425, 2013
7UY6
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BU of 7uy6 by Molmil
Tetrahymena telomerase at 2.9 Angstrom resolution
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
8DS1
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BU of 8ds1 by Molmil
Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence
Descriptor: 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, SODIUM ION
Authors:Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
Deposit date:2022-07-21
Release date:2022-09-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8K1I
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BU of 8k1i by Molmil
Crystal structure of arabinose dehydrogenase from Candida auris
Descriptor: NADP-dependent oxidoreductase domain-containing protein
Authors:Zhang, J, Bai, X, He, S.R, Zhao, Z.D.
Deposit date:2023-07-11
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of arabinose dehydrogenase from Candida auris
To Be Published
7UY8
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BU of 7uy8 by Molmil
Tetrahymena Polymerase alpha-Primase
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
8UE1
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BU of 8ue1 by Molmil
Crystal Structure of Human Fructosamine-3-kinase (FN3K)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fructosamine-3-kinase
Authors:Lokhandwala, J, Tran, T.H, Binning, J.M.
Deposit date:2023-09-29
Release date:2024-08-07
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis for FN3K-mediated protein deglycation.
Structure, 2024
8DZF
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BU of 8dzf by Molmil
Cryo-EM structure of bundle-forming pilus extension ATPase from E.coli in the presence of AMP-PNP (class-2)
Descriptor: BfpD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION
Authors:Nayak, A.R, Zhao, J, Donnenberg, M.S, Samso, M.
Deposit date:2022-08-07
Release date:2022-10-26
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli.
Mbio, 13, 2022
1L8O
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Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
Descriptor: L-3-phosphoserine phosphatase, PHOSPHATE ION, SERINE
Authors:Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y.
Deposit date:2002-03-21
Release date:2003-04-01
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
J.Biol.Chem., 277, 2002
7UAV
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Structure of Clostridium botulinum prophage Tad1 in apo state
Descriptor: ABC transporter ATPase
Authors:Lu, A, Leavitt, A, Yirmiya, E, Amitai, G, Garb, J, Morehouse, B.R, Hobbs, S.J, Sorek, R, Kranzusch, P.J.
Deposit date:2022-03-14
Release date:2022-10-05
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Viruses inhibit TIR gcADPR signalling to overcome bacterial defence.
Nature, 611, 2022

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