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8DS2

Structure of SARS-CoV-2 Mpro in complex with the nsp13-nsp14 (C13) cut site sequence (form 2)

Summary for 8DS2
Entry DOI10.2210/pdb8ds2/pdb
Descriptor3C-like proteinase nsp5, GLYCEROL, SODIUM ION, ... (4 entities in total)
Functional Keywordsviral protease, sars-cov-2, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2
Total number of polymer chains2
Total formula weight68733.19
Authors
Lee, J.,Kenward, C.,Worrall, L.J.,Vuckovic, M.,Paetzel, M.,Strynadka, N.C.J. (deposition date: 2022-07-21, release date: 2022-09-28, Last modification date: 2023-11-15)
Primary citationLee, J.,Kenward, C.,Worrall, L.J.,Vuckovic, M.,Gentile, F.,Ton, A.T.,Ng, M.,Cherkasov, A.,Strynadka, N.C.J.,Paetzel, M.
X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13:5196-5196, 2022
Cited by
PubMed: 36057636
DOI: 10.1038/s41467-022-32854-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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