2C2H
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![BU of 2c2h by Molmil](/molmil-images/mine/2c2h) | CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Debreczeni, J.E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, von Delft, F, Doyle, D, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A. | Deposit date: | 2005-09-29 | Release date: | 2005-10-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of the Human Rac3 in Complex with Gdp To be Published
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8H2H
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![BU of 8h2h by Molmil](/molmil-images/mine/8h2h) | Cryo-EM structure of a Group II Intron Complexed with its Reverse Transcriptase | Descriptor: | Group II intron-encoded protein LtrA, LtrB, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3') | Authors: | Liu, N, Dong, X.L, Qu, G.S, Wang, J, Wang, H.W, Belfort, M. | Deposit date: | 2022-10-06 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Functionalized graphene grids with various charges for single-particle cryo-EM. Nat Commun, 13, 2022
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6LDF
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![BU of 6ldf by Molmil](/molmil-images/mine/6ldf) | |
6LDE
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![BU of 6lde by Molmil](/molmil-images/mine/6lde) | |
6LDG
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![BU of 6ldg by Molmil](/molmil-images/mine/6ldg) | |
4L8Z
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![BU of 4l8z by Molmil](/molmil-images/mine/4l8z) | Crystal structure of Human Hsp90 with RL1 | Descriptor: | Heat shock protein HSP 90-alpha, [5-(6-bromo[1,2,4]triazolo[4,3-a]pyridin-3-yl)-2,4-dihydroxyphenyl](3,4-dihydroisoquinolin-2(1H)-yl)methanone | Authors: | Li, J, Ren, J, Yang, M, Xiong, B, He, J. | Deposit date: | 2013-06-18 | Release date: | 2014-06-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization Bioorg.Med.Chem.Lett., 24, 2014
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7YT9
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![BU of 7yt9 by Molmil](/molmil-images/mine/7yt9) | crystal structure of AGD1-4 of Arabidopsis AGDP3 | Descriptor: | AGD1-4 of Arabidopsis AGDP3 | Authors: | Zhou, X, Du, J. | Deposit date: | 2022-08-13 | Release date: | 2022-10-12 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The H3K9me2-binding protein AGDP3 limits DNA methylation and transcriptional gene silencing in Arabidopsis. J Integr Plant Biol, 64, 2022
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7YTA
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6RU6
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![BU of 6ru6 by Molmil](/molmil-images/mine/6ru6) | Crystal structure of Casein Kinase I delta (CK1d) in complex with monophosphorylated p63 PAD1P peptide | Descriptor: | 1,2-ETHANEDIOL, Casein kinase I isoform delta, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Chaikuad, A, Tuppi, M, Gebel, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Dotsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2019-05-27 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | p63 uses a switch-like mechanism to set the threshold for induction of apoptosis. Nat.Chem.Biol., 16, 2020
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3EP2
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![BU of 3ep2 by Molmil](/molmil-images/mine/3ep2) | Model of Phe-tRNA(Phe) in the ribosomal pre-accommodated state revealed by cryo-EM | Descriptor: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | Authors: | Frank, J, Li, W, Agirrezabala, X. | Deposit date: | 2008-09-29 | Release date: | 2008-12-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. Embo J., 27, 2008
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6OJE
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![BU of 6oje by Molmil](/molmil-images/mine/6oje) | Dimeric structure of LRRK2 GTPase domain | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION | Authors: | Hoang, Q.Q, Wu, C.X, Liao, J, Park, Y. | Deposit date: | 2019-04-11 | Release date: | 2020-10-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for conformational plasticity in the GTPase domain of the Parkinson's disease-associated protein LRRK2 To Be Published
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7Z3A
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![BU of 7z3a by Molmil](/molmil-images/mine/7z3a) | AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACS101 heavy chain, ... | Authors: | van Schooten, J, Ward, A. | Deposit date: | 2022-03-02 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nat Commun, 13, 2022
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5XWR
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![BU of 5xwr by Molmil](/molmil-images/mine/5xwr) | Crystal Structure of RBBP4-peptide complex | Descriptor: | Histone-binding protein RBBP4, MET-SER-ARG-ARG-LYS-GLN-ALA-LYS-PRO-GLN-HIS-ILE | Authors: | Jobichen, C, Lui, B.H, Daniel, G.T, Sivaraman, J. | Deposit date: | 2017-06-30 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8H99
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![BU of 8h99 by Molmil](/molmil-images/mine/8h99) | Crystal structure of E. coli ThrS catalytic domain mutant | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, IMIDAZOLE, MAGNESIUM ION, ... | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8H9C
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![BU of 8h9c by Molmil](/molmil-images/mine/8h9c) | Crystal structure of chemically modified E. coli ThrS catalytic domain 4 | Descriptor: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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8H98
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![BU of 8h98 by Molmil](/molmil-images/mine/8h98) | Crystal structure of chemically modified E. coli ThrS catalytic domain 1 | Descriptor: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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7ZF1
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![BU of 7zf1 by Molmil](/molmil-images/mine/7zf1) | Structure of ubiquitinated FANCI in complex with FANCD2 and double-stranded DNA | Descriptor: | DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ... | Authors: | Lemonidis, K, Rennie, M.L, Arkinson, C, Streetley, J, Clarke, M, Chaugule, V.K, Walden, H. | Deposit date: | 2022-03-31 | Release date: | 2022-11-16 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination. Embo J., 42, 2023
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8H9B
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![BU of 8h9b by Molmil](/molmil-images/mine/8h9b) | Crystal structure of chemically modified E. coli ThrS catalytic domain 3 | Descriptor: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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5ZYV
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6LT4
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![BU of 6lt4 by Molmil](/molmil-images/mine/6lt4) | AAA+ ATPase, ClpL from Streptococcus pneumoniae: ATPrS-bound | Descriptor: | ATP-dependent Clp protease, ATP-binding subunit, MAGNESIUM ION, ... | Authors: | Kim, G, Lee, S.G, Han, S, Jung, J, Jeong, H.S, Hyun, J.K, Rhee, D.K, Kim, H.M, Lee, S. | Deposit date: | 2020-01-21 | Release date: | 2021-01-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | ClpL is a functionally active tetradecameric AAA+ chaperone, distinct from hexameric/dodecameric ones. Faseb J., 34, 2020
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8H8J
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![BU of 8h8j by Molmil](/molmil-images/mine/8h8j) | Lodoxamide-bound GPR35 in complex with G13 | Descriptor: | 2,2'-[(2-chloro-5-cyano-1,3-phenylene)bis(azanediyl)]bis(oxoacetic acid), CALCIUM ION, CHOLESTEROL, ... | Authors: | Yuan, Q, Duan, J, Liu, Q, Xu, H.E, Jiang, Y. | Deposit date: | 2022-10-23 | Release date: | 2023-02-08 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Insights into divalent cation regulation and G 13 -coupling of orphan receptor GPR35. Cell Discov, 8, 2022
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8H9A
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![BU of 8h9a by Molmil](/molmil-images/mine/8h9a) | Crystal structure of chemically modified E. coli ThrS catalytic domain 2 | Descriptor: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
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6AEE
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![BU of 6aee by Molmil](/molmil-images/mine/6aee) | Crystal structure of the four Ig-like domains of LILRB1 complexed with HLA-G | Descriptor: | 9 Mer Peptide (RL9) From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Wang, Q, Song, H, Qi, J, Gao, G.F. | Deposit date: | 2018-08-04 | Release date: | 2019-07-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.303 Å) | Cite: | Structures of the four Ig-like domain LILRB2 and the four-domain LILRB1 and HLA-G1 complex. Cell. Mol. Immunol., 2019
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6RJN
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![BU of 6rjn by Molmil](/molmil-images/mine/6rjn) | Crystal structure of a Fungal Catalase at 2.3 Angstroms | Descriptor: | CHLORIDE ION, Catalase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Gomez, S, Navas-Yuste, S, Payne, A.M, Rivera, W, Lopez-Estepa, M, Brangbour, C, Fulla, D, Juanhuix, J, Fernandez, F.J, Vega, M.C. | Deposit date: | 2019-04-28 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes. Free Radic. Biol. Med., 141, 2019
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6LMS
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![BU of 6lms by Molmil](/molmil-images/mine/6lms) | |