7Z3A

AMC009 SOSIPv5.2 in complex with Fabs ACS101 and ACS124

This is a non-PDB format compatible entry.

Summary for 7Z3A

• Entry DOI: 10.2210/pdb7z3a/pdb
• EMDB information: 14474
• Descriptor: AMC009 SOSIPv5.2 envelope glycoprotein gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: hiv-1, antibodies, cd4-binding site, gp41-gp120 interface, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 16
• Total formula weight: 374065.69

Authors

van Schooten, J.,Ward, A. (deposition date: 2022-03-02, release date: 2022-08-10, Last modification date: 2022-08-17)

• Primary citation: van Schooten, J.,Farokhi, E.,Schorcht, A.,van den Kerkhof, T.L.G.M.,Gao, H.,van der Woude, P.,Burger, J.A.,Meesters, T.G.R.,Bijl, T.,Ghalaiyini, R.,Turner, H.L.,Dorning, J.,van Schaik, B.D.C.,van Kampen, A.H.C.,Labranche, C.C.,Stanfield, R.L.,Sok, D.,Montefiori, D.C.,Burton, D.R.,Seaman, M.S.,Ozorowski, G.,Wilson, I.A.,Sanders, R.W.,Ward, A.B.,van Gils, M.J.; Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.; Nat Commun, 13:4515-4515, 2022; PubMed: 35922441; DOI: 10.1038/s41467-022-32208-0

Experimental method

ELECTRON MICROSCOPY (3.95 Å)