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PDB: 42706 results

6OII
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BU of 6oii by Molmil
Structure of Aedes aegypti OBP22 in the complex with arachidonic acid
Descriptor: 1,2-ETHANEDIOL, AAEL005772-PA, ARACHIDONIC ACID, ...
Authors:Jones, D.N, Wang, J.
Deposit date:2019-04-09
Release date:2019-05-08
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail.
Sci Rep, 10, 2020
1JF2
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BU of 1jf2 by Molmil
Crystal Structure of W92F obelin mutant from Obelia longissima at 1.72 Angstrom resolution
Descriptor: C2-HYDROPEROXY-COELENTERAZINE, obelin
Authors:Liu, Z.-J, Vysotski, E.S, Deng, L, Markova, S.V, Lee, J, Rose, J.P, Wang, B.-C.
Deposit date:2001-06-19
Release date:2001-07-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Violet bioluminescence and fast kinetics from W92F obelin: structure-based proposals for the bioluminescence triggering and the identification of the emitting species.
Biochemistry, 42, 2003
6LJI
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BU of 6lji by Molmil
X-ray structure of synthetic GB1 domain with mutations K10(DVA), T11V
Descriptor: Immunoglobulin G-binding protein G
Authors:Penmatsa, A, Chatterjee, J, Majumder, P, Khatri, B.
Deposit date:2019-12-16
Release date:2020-08-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.843 Å)
Cite:Increasing protein stability by engineering the n -> pi * interaction at the beta-turn.
Chem Sci, 11, 2020
6ORL
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BU of 6orl by Molmil
RF1 pre-accommodated 70S complex at 24 ms
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OU9
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BU of 6ou9 by Molmil
Asymmetric focused reconstruction of human norovirus GI.7 Houston strain VLP asymmetric unit in T=3 symmetry
Descriptor: Major capsid protein
Authors:Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
Deposit date:2019-05-04
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUT
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BU of 6out by Molmil
Asymmetric focused reconstruction of human norovirus GI.1 Norwalk strain VLP asymmetric unit in T=3 symmetry
Descriptor: Capsid protein VP1
Authors:Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
Deposit date:2019-05-05
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
5ZM5
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BU of 5zm5 by Molmil
Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution
Descriptor: CHOLESTEROL, Oxysterol-binding protein-related protein 1
Authors:Dong, J, Wang, J, Wu, J.W.
Deposit date:2018-04-01
Release date:2019-02-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
6ODD
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BU of 6odd by Molmil
Crystal structure of the human complex ACP-ISD11
Descriptor: Acyl carrier protein, mitochondrial, CALCIUM ION, ...
Authors:Herrera, M.G, Noguera, M.E, Klinke, S, Santos, J.
Deposit date:2019-03-26
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Human ACP-ISD11 Heterodimer.
Biochemistry, 58, 2019
2Y0C
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BU of 2y0c by Molmil
BceC mutation Y10S
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ...
Authors:Rocha, J, Popescu, A.O, Borges, P, Mil-Homens, D, Sa-Correia, I, Fialho, A.M, Frazao, C.
Deposit date:2010-12-02
Release date:2011-07-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of Burkholderia Cepacia Udp-Glucose Dehydrogenase (Ugd) Bcec and Role of Tyr10 in Final Hydrolysis of Ugd Thioester Intermediate.
J.Bacteriol., 193, 2011
6LDF
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BU of 6ldf by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96K AB5
Descriptor: CHLORIDE ION, HEME C, ZINC ION, ...
Authors:Song, W.J, Yu, J.
Deposit date:2019-11-21
Release date:2021-03-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021
3CJ5
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BU of 3cj5 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide, RNA-directed RNA polymerase
Authors:Hendle, j.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
6LDE
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BU of 6lde by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96V AB5
Descriptor: CHLORIDE ION, HEME C, ZINC ION, ...
Authors:Song, W.J, Yu, J.
Deposit date:2019-11-21
Release date:2021-03-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021
2J8Z
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BU of 2j8z by Molmil
Crystal Structure of human P53 inducible oxidoreductase (TP53I3,PIG3)
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, QUINONE OXIDOREDUCTASE
Authors:Pike, A.C.W, Shafqat, N, Debreczeni, J, Johansson, C, Haroniti, A, Gileadi, O, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, von Delft, F, Porte, S, Fita, I, Pares, J, Pares, X, Oppermann, U.
Deposit date:2006-10-31
Release date:2006-11-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-Dimensional Structure and Enzymatic Function of Proapoptotic Human P53-Inducible Quinone Oxidoreductase Pig3.
J.Biol.Chem., 284, 2009
6LDG
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BU of 6ldg by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96I AB5
Descriptor: CHLORIDE ION, HEME C, MAGNESIUM ION, ...
Authors:Song, W.J, Yu, J.
Deposit date:2019-11-21
Release date:2021-03-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021
6OF8
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BU of 6of8 by Molmil
Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CamKII-alpha hub domain
Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, POTASSIUM ION
Authors:McSpadden, E.D, Chi, C.C, Gee, C.L, Kuriyan, J.
Deposit date:2019-03-28
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/calmodulin-dependent protein kinase II.
Protein Sci., 28, 2019
5ZO2
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BU of 5zo2 by Molmil
Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain in complex with mouse nectin-like molecule 1 (mNecl-1) Ig1 domain, 3.3A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 3, Cell adhesion molecule 4
Authors:Liu, X, An, T, Li, D, Fan, Z, Xiang, P, Li, C, Ju, W, Li, J, Hu, G, Qin, B, Yin, B, Wojdyla, J.A, Wang, M, Yuan, J, Qiang, B, Shu, P, Cui, S, Peng, X.
Deposit date:2018-04-12
Release date:2019-01-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8B70
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BU of 8b70 by Molmil
KimA from B. subtilis with nucleotide second-messenger c-di-AMP bound
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ...
Authors:Vonck, J, Wieferig, J.P.
Deposit date:2022-09-28
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cyclic di-AMP traps proton-coupled K + transporters of the KUP family in an inward-occluded conformation.
Nat Commun, 14, 2023
4O7H
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BU of 4o7h by Molmil
Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460
Descriptor: Glutathione S-transferase
Authors:Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Attonito, J.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2013-12-24
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460
TO BE PUBLISHED
2NY2
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BU of 2ny2 by Molmil
HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ...
Authors:Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
Deposit date:2006-11-20
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
8PK4
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BU of 8pk4 by Molmil
Cryo EM structure of the type 5A polymorph of alpha-synuclein.
Descriptor: Alpha-synuclein
Authors:Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R.
Deposit date:2023-06-24
Release date:2024-05-29
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation.
Elife, 12, 2024
8B71
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BU of 8b71 by Molmil
Upright KimA dimer with bound c-di-AMP from B. subtilis
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Potassium transporter KimA
Authors:Vonck, J, Wieferig, J.P.
Deposit date:2022-09-28
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cyclic di-AMP traps proton-coupled K + transporters of the KUP family in an inward-occluded conformation.
Nat Commun, 14, 2023
6I7O
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BU of 6i7o by Molmil
The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition.
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Cheng, J, Becker, T, Beckmann, R.
Deposit date:2018-11-16
Release date:2019-01-16
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
4P0E
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BU of 4p0e by Molmil
YhdE E33A (p212121 space group)
Descriptor: Maf-like protein YhdE, PHOSPHATE ION, SULFATE ION
Authors:Jia, Z, Zheng, J, Jin, J, Wang, N.
Deposit date:2014-02-20
Release date:2014-04-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:YhdE E33A
To Be Published
6ONT
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BU of 6ont by Molmil
Structure of the Francisella response regulator 1452 receiver domain
Descriptor: CALCIUM ION, CHLORIDE ION, SODIUM ION, ...
Authors:Milton, M.E, Cavanagh, J.
Deposit date:2019-04-22
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Francisella novicidaTwo-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production.
Front Cell Infect Microbiol, 10, 2020
4O6F
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BU of 4o6f by Molmil
Structural Basis of Estrogen Receptor Alpha Methylation Mediated by Histone Methyltransferase SmyD2
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Estrogen receptor, N-lysine methyltransferase SMYD2, ...
Authors:Jiang, Y, Trescott, L, Holcomb, J, Brunzelle, J, Sirinupong, N, Shi, X, Yang, Z.
Deposit date:2013-12-20
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.822 Å)
Cite:Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014

225158

數據於2024-09-18公開中

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