6PZP
 
 | | Crystal structure of caspase-1 in complex with VX-765 | | Descriptor: | Caspase-1, N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide | | Authors: | Yang, J, Liu, Z, Xiao, T.S. | | Deposit date: | 2019-08-01 | | Release date: | 2020-08-05 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Crystal structure of caspase-1 in complex with VX-765
To Be Published
|
|
7RBS
 | | The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with human ISG15 | | Descriptor: | Papain-like protease, Ubiquitin-like protein ISG15, ZINC ION | | Authors: | Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Wydorski, P, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-07-06 | | Release date: | 2021-09-29 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.98 Å) | | Cite: | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.
Nat Commun, 14, 2023
|
|
8TES
 | | Human cytomegalovirus portal vertex, virion configuration 2 (VC2) | | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | | Authors: | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | | Deposit date: | 2023-07-06 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM.
Sci Adv, 10, 2024
|
|
6X0Q
 | |
7XZ9
 | |
7XZD
 | |
7XZF
 | | Wild type of the N-terminal domain of fucoidan lyase FdlA | | Descriptor: | Fucoidan lyase, GLYCEROL, IMIDAZOLE, ... | | Authors: | Wang, J, Li, M, Pan, X. | | Deposit date: | 2022-06-02 | | Release date: | 2022-09-28 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural and Biochemical Analysis Reveals Catalytic Mechanism of Fucoidan Lyase from Flavobacterium sp. SA-0082.
Mar Drugs, 20, 2022
|
|
6WDO
 | | Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+ | | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | | Authors: | Feng, L, Zhang, J, Fan, M. | | Deposit date: | 2020-04-01 | | Release date: | 2020-05-27 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex.
Nature, 582, 2020
|
|
2W6K
 | | The crystal structure at 1.7 A resolution of CobE, a protein from the cobalamin (vitamin B12) biosynthetic pathway | | Descriptor: | COBE, GLYCEROL, SULFATE ION | | Authors: | Vevodova, J, Smith, D, McGoldrick, H, Deery, E, Murzin, A.G, Warren, M.J, Wilson, K.S. | | Deposit date: | 2008-12-18 | | Release date: | 2008-12-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
|
|
2P9M
 | | Crystal structure of conserved hypothetical protein MJ0922 from Methanocaldococcus jannaschii DSM 2661 | | Descriptor: | Hypothetical protein MJ0922 | | Authors: | Zhao, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhu, J, Swindell II, J.T, Chen, L, Fu, Z.-Q, Charz, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-26 | | Release date: | 2007-07-03 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Crystal structure of conserved hypothetical protein MJ0922 from Methanocaldococcus jannaschii DSM 2661
To be Published
|
|
6Q7M
 | | Spiral structure of E. coli RavA in the RavA-LdcI cage-like complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATPase RavA, Inducible lysine decarboxylase, ... | | Authors: | Arragain, B, Felix, J, Malet, H, Gutsche, I, Jessop, M. | | Deposit date: | 2018-12-13 | | Release date: | 2020-02-12 | | Last modified: | 2020-02-19 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
|
|
8TEB
 | | Structure of MKbur | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Peat, T.S, Newman, J, Esquirol, L, Nebl, T, Scott, C, Vickers, C, Sainsbury, F. | | Deposit date: | 2023-07-06 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Characterization of novel mevalonate kinases from the tardigrade Ramazzottius varieornatus and the psychrophilic archaeon Methanococcoides burtonii.
Acta Crystallogr D Struct Biol, 80, 2024
|
|
7XZ8
 | |
7XZB
 | |
8TET
 | | Human cytomegalovirus portal vertex, non-infectious enveloped particle (NIEP) configuration 1 (NC1) | | Descriptor: | Capsid vertex component 1, Capsid vertex component 2, Large structural phosphoprotein, ... | | Authors: | Jih, J, Liu, Y.T, Liu, W, Zhou, H. | | Deposit date: | 2023-07-07 | | Release date: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.26 Å) | | Cite: | The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM.
Sci Adv, 10, 2024
|
|
7XZA
 | |
7XZE
 | |
5WX8
 | | Human herpesvirus 6A immediate early protein 2 C-terminal domain | | Descriptor: | Immediate-early protein 2 | | Authors: | Nishimura, M, Wang, J, Wakata, A, Sakamoto, K, Mori, Y. | | Deposit date: | 2017-01-06 | | Release date: | 2017-08-02 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 2.
J. Virol., 91, 2017
|
|
8BRP
 | | Peptide Arginase OspR from the cyanobacterium Kamptonema sp. | | Descriptor: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Mordhorst, S, Badmann, T, Boesch, N.M, Morinaka, B.I, Rach, H, Piel, J, Groll, M, Vagstadt, A.L. | | Deposit date: | 2022-11-23 | | Release date: | 2023-03-01 | | Last modified: | 2023-03-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase.
Acs Chem.Biol., 18, 2023
|
|
7RBR
 | | The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with a Lys48-linked di-ubiquitin | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Papain-like protease, ... | | Authors: | Osipiuk, J, Tesar, C, Endres, M, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-07-06 | | Release date: | 2021-09-29 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.
Nat Commun, 14, 2023
|
|
3K5K
 | | Discovery of a 2,4-Diamino-7-aminoalkoxy-quinazoline as a Potent Inhibitor of Histone Lysine Methyltransferase, G9a | | Descriptor: | 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine, CHLORIDE ION, Histone-lysine N-methyltransferase, ... | | Authors: | Dong, A, Wasney, G.A, Liu, F, Chen, X, Allali-Hassani, A, Senisterra, G, Chau, I, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Frye, S.V, Bochkarev, A, Brown, P.J, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-10-07 | | Release date: | 2009-11-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.
J.Med.Chem., 52, 2009
|
|
7XZ7
 | |
2P5Y
 | | Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase | | Authors: | Fu, Z.-Q, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhu, J, Swindell, J.T, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-16 | | Release date: | 2007-04-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Crystal structure of Thermus thermophilus HB8 UDP-glucose 4-epimerase complex with NAD
To be Published
|
|
8BDW
 | | Crystal structure of CnaB2 domain from Lactobacillus plantarum | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell surface adherence protein,collagen-binding domain, LPXTG-motif cell wall anchor, ... | | Authors: | Taberman, H, Hakanpaa, J, Linder, M.B, Aranko, A.S. | | Deposit date: | 2022-10-20 | | Release date: | 2023-02-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Biomolecular Click Reactions Using a Minimal pH-Activated Catcher/Tag Pair for Producing Native-Sized Spider-Silk Proteins.
Angew.Chem.Int.Ed.Engl., 62, 2023
|
|
6WJG
 | | PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma | | Descriptor: | DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit | | Authors: | Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S. | | Deposit date: | 2020-04-13 | | Release date: | 2020-12-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (6.2 Å) | | Cite: | Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
|
|
