4IFP
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![BU of 4ifp by Molmil](/molmil-images/mine/4ifp) | X-ray Crystal Structure of Human NLRP1 CARD Domain | Descriptor: | MALONATE ION, Maltose-binding periplasmic protein,NACHT, LRR and PYD domains-containing protein 1, ... | Authors: | Jin, T, Curry, J, Smith, P, Jiang, J, Xiao, T. | Deposit date: | 2012-12-14 | Release date: | 2013-04-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9948 Å) | Cite: | Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1. Proteins, 81, 2013
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1UVX
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![BU of 1uvx by Molmil](/molmil-images/mine/1uvx) | Heme-ligand tunneling on group I truncated hemoglobins | Descriptor: | CYANIDE ION, GLOBIN LI637, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Milani, M, Pesce, A, Ouellet, Y, Dewilde, S, Friedman, J, Ascenzi, P, Guertin, M, Bolognesi, M. | Deposit date: | 2004-01-27 | Release date: | 2004-03-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Heme-Ligand Tunneling in Group I Truncated Hemoglobins J.Biol.Chem., 279, 2004
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4Z7O
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![BU of 4z7o by Molmil](/molmil-images/mine/4z7o) | Integrin alphaIIbbeta3 in complex with AGDV peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Lin, F.Y, Zhu, J, Springer, T.A. | Deposit date: | 2015-04-07 | Release date: | 2016-01-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | beta-Subunit Binding Is Sufficient for Ligands to Open the Integrin alpha IIb beta 3 Headpiece. J.Biol.Chem., 291, 2016
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4IHC
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![BU of 4ihc by Molmil](/molmil-images/mine/4ihc) | Crystal structure of probable mannonate dehydratase Dd703_0947 (target EFI-502222) from Dickeya dadantii Ech703 | Descriptor: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N.F, Stead, M, Love, J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2012-12-18 | Release date: | 2013-01-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of mannonate dehydratase Dd703_0947 from Dickeya dadantii Ech703 To be Published
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1KMA
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![BU of 1kma by Molmil](/molmil-images/mine/1kma) | NMR Structure of the Domain-I of the Kazal-type Thrombin Inhibitor Dipetalin | Descriptor: | DIPETALIN | Authors: | Schlott, B, Wohnert, J, Icke, C, Hartmann, M, Ramachandran, R, Guhrs, K.-H, Glusa, E, Flemming, J, Gorlach, M, Grosse, F, Ohlenschlager, O. | Deposit date: | 2001-12-14 | Release date: | 2002-05-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies. J.Mol.Biol., 318, 2002
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4IKB
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![BU of 4ikb by Molmil](/molmil-images/mine/4ikb) | Crystal structure of SNX11 PX domain | Descriptor: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CHLORIDE ION, SODIUM ION, ... | Authors: | Xu, J, Xu, T, Liu, J. | Deposit date: | 2012-12-26 | Release date: | 2013-04-24 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure of Sorting Nexin 11 (SNX11) Reveals a Novel Extended PX Domain (PXe Domain) Critical for the Inhibition of Sorting Nexin 10 (SNX10) Induced Vacuolation to be published
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4ZF7
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![BU of 4zf7 by Molmil](/molmil-images/mine/4zf7) | Crystal structure of ferret interleukin-2 | Descriptor: | DI(HYDROXYETHYL)ETHER, Interleukin 2, PENTAETHYLENE GLYCOL, ... | Authors: | Ren, B, Newman, J, McKinstry, W.J, Adams, T.E. | Deposit date: | 2015-04-21 | Release date: | 2015-11-04 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | Structural and functional characterisation of ferret interleukin-2. Dev.Comp.Immunol., 55, 2015
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3V96
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![BU of 3v96 by Molmil](/molmil-images/mine/3v96) | Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1) | Descriptor: | CALCIUM ION, Metalloproteinase inhibitor 1, PHOSPHATE ION, ... | Authors: | Batra, J, Soares, A.S, Radisky, E.S. | Deposit date: | 2011-12-23 | Release date: | 2012-03-28 | Last modified: | 2012-07-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure. J.Biol.Chem., 287, 2012
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3DBF
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![BU of 3dbf by Molmil](/molmil-images/mine/3dbf) | Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 562 | Descriptor: | 4-({1-[3-(3-amino-3-oxopropyl)-5-chlorophenyl]-3-methyl-1H-pyrazolo[4,3-c]pyridin-6-yl}amino)-3-methoxy-N-(1-methylpipe ridin-4-yl)benzamide, Polo-like kinase | Authors: | Elling, R.A, Zhu, J, Barr, K.J, Romanowski, M.J. | Deposit date: | 2008-05-31 | Release date: | 2008-10-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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4ZGB
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![BU of 4zgb by Molmil](/molmil-images/mine/4zgb) | Structure of untreated lipase from Thermomyces lanuginosa at 2.3 A resolution | Descriptor: | Lipase | Authors: | Kumar, M, Sinha, M, Mukherjee, J, Gupta, M.N, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2015-04-22 | Release date: | 2015-05-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enhancement of stability of a lipase by subjecting to three phase partitioning (TPP): structures of native and TPP-treated lipase from Thermomyces lanuginosa Sustain Chem Process, 2015
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6ELE
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![BU of 6ele by Molmil](/molmil-images/mine/6ele) | FAB Fragment. AbVance: Increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, fAB heavy chain, ... | Authors: | Benz, J, Weigand, S, Dengl, S, Schlothauer, T, Auer, J, Ehler, A, Kettenberger, H, Lorenz, S, Hirschheydt, T, Georges, G. | Deposit date: | 2017-09-28 | Release date: | 2017-11-08 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in antibody drug discovery To Be Published
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6CTY
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![BU of 6cty by Molmil](/molmil-images/mine/6cty) | Crystal structure of dihydroorotase pyrC from Yersinia pestis in complex with zinc and malate at 2.4 A resolution | Descriptor: | D-MALATE, Dihydroorotase, ZINC ION | Authors: | Lipowska, J, Shabalin, I.G, Winsor, J, Woinska, M, Cooper, D.R, Kwon, K, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-03-23 | Release date: | 2018-04-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae. Int.J.Biol.Macromol., 136, 2019
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3VQ5
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![BU of 3vq5 by Molmil](/molmil-images/mine/3vq5) | HIV-1 IN core domain in complex with N-METHYL-1-(4-METHYL-2-PHENYL-1,3-THIAZOL-5-YL)METHANAMINE | Descriptor: | CADMIUM ION, CHLORIDE ION, N-methyl-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)methanamine, ... | Authors: | Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. | Deposit date: | 2012-03-20 | Release date: | 2013-01-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
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2Q9O
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![BU of 2q9o by Molmil](/molmil-images/mine/2q9o) | Near-atomic resolution structure of a Melanocarpus albomyces laccase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Hakulinen, N, Rouvinen, J. | Deposit date: | 2007-06-13 | Release date: | 2008-03-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | A near atomic resolution structure of a Melanocarpus albomyces laccase. J.Struct.Biol., 162, 2008
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2CTH
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![BU of 2cth by Molmil](/molmil-images/mine/2cth) | CYTOCHROME C3 FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH | Descriptor: | CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Simoes, P, Matias, P.M, Morais, J, Wilson, K, Dauter, Z, Carrondo, M.A. | Deposit date: | 1997-06-18 | Release date: | 1997-12-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Refinement of the Three-Dimensional Structures of Cytochromes C3 from Desulfovibrio Vulgaris Hildenborough at 1.67 Angstrom Resolution and from Desulfovibrio Desulfuricans Atcc 27774 at 1.6 Angstrom Resolution Inorg.Chim.Acta., 273, 1998
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2CAG
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![BU of 2cag by Molmil](/molmil-images/mine/2cag) | CATALASE COMPOUND II | Descriptor: | CATALASE COMPOUND II, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gouet, P, Jouve, H.M, Hajdu, J. | Deposit date: | 1996-06-12 | Release date: | 1996-12-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy. Nat.Struct.Biol., 3, 1996
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7XN6
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![BU of 7xn6 by Molmil](/molmil-images/mine/7xn6) | Cryo-EM structure of CopC-CaM-caspase-3 with ADPR-deacylization | Descriptor: | Arginine ADP-riboxanase CopC, Calmodulin-1, Caspase-3, ... | Authors: | Zhang, K, Peng, T, Tao, X.Y, Tian, M, Li, Y.X, Wang, Z, Ma, S.F, Hu, S.F, Pan, X, Xue, J, Luo, J.W, Wu, Q.L, Fu, Y, Li, S. | Deposit date: | 2022-04-28 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin. Mol.Cell, 82, 2022
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2Q1A
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![BU of 2q1a by Molmil](/molmil-images/mine/2q1a) | 2-keto-3-deoxy-D-arabinonate dehydratase complexed with magnesium and 2-oxobutyrate | Descriptor: | 2-KETOBUTYRIC ACID, 2-keto-3-deoxy-D-arabinonate dehydratase, MAGNESIUM ION | Authors: | Barends, T, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | Deposit date: | 2007-05-24 | Release date: | 2008-04-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily. J.Mol.Biol., 379, 2008
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7YJI
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![BU of 7yji by Molmil](/molmil-images/mine/7yji) | |
4TQN
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![BU of 4tqn by Molmil](/molmil-images/mine/4tqn) | |
4TU4
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![BU of 4tu4 by Molmil](/molmil-images/mine/4tu4) | Crystal structure of ATAD2A bromodomain complexed with 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(phenylsulfonyl)amino]benzoicacid | Descriptor: | 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(phenylsulfonyl)amino]benzoic acid, ATPase family AAA domain-containing protein 2, CHLORIDE ION, ... | Authors: | Poncet-Montange, G, Zhan, Y, Bardenhagen, J, Petrocchi, A, Leo, E, Shi, X, Lee, G, Leonard, P, Geck Do, M, Cardozo, M, Palmer, W, Andersen, J, Jones, P, Ladbury, J. | Deposit date: | 2014-06-23 | Release date: | 2014-12-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Biochem.J., 466, 2015
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2C8D
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![BU of 2c8d by Molmil](/molmil-images/mine/2c8d) | Structure of the ARTT motif Q212A mutant C3bot1 Exoenzyme (Free state, crystal form I) | Descriptor: | MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION | Authors: | Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A. | Deposit date: | 2005-12-03 | Release date: | 2007-02-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes. Protein Sci., 17, 2008
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4Z50
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![BU of 4z50 by Molmil](/molmil-images/mine/4z50) | Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20D25N with Tucked Flap | Descriptor: | CHLORIDE ION, GLYCEROL, Protease, ... | Authors: | Agniswamy, J, Shen, C.-H, Weber, I.T. | Deposit date: | 2015-04-02 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Conformational variation of an extreme drug resistant mutant of HIV protease. J.Mol.Graph.Model., 62, 2015
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4IJB
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![BU of 4ijb by Molmil](/molmil-images/mine/4ijb) | Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR288 | Descriptor: | Engineered Protein OR288 | Authors: | Vorobiev, S, Su, M, Bick, M.J, Seetharaman, J, Khare, S, Maglaqui, M, Xiao, R, Lee, D, Day, A, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Hunt, J, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-12-21 | Release date: | 2013-01-16 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (1.739 Å) | Cite: | Crystal Structure of Engineered Protein OR288. To be Published
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2C8E
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![BU of 2c8e by Molmil](/molmil-images/mine/2c8e) | Structure of the ARTT motif E214N mutant C3bot1 Exoenzyme (Free state, crystal form III) | Descriptor: | MONO-ADP-RIBOSYLTRANSFERASE C3, SULFATE ION | Authors: | Stura, E.A, Menetrey, J, Flatau, G, Boquet, P, Menez, A. | Deposit date: | 2005-12-03 | Release date: | 2007-02-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes. Protein Sci., 17, 2008
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