4Z50

Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20D25N with Tucked Flap

Summary for 4Z50

Related4Z4X
DescriptorProtease, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
Functional Keywordshiv-1 protease, hydrolase
Biological sourceHuman immunodeficiency virus 1
Total number of polymer chains4
Total molecular weight43657.46
Authors
Agniswamy, J.,Shen, C.-H.,Weber, I.T. (deposition date: 2015-04-02, release date: 2015-10-14, Last modification date: 2017-09-27)
Primary citation
Shen, C.H.,Chang, Y.C.,Agniswamy, J.,Harrison, R.W.,Weber, I.T.
Conformational variation of an extreme drug resistant mutant of HIV protease.
J.Mol.Graph.Model., 62:87-96, 2015
PubMed: 26397743 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmgm.2015.09.006
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.45 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.191501.2%5.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution