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PDB: 42550 件

8HVR
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Cryo-EM structure of AfsR-dependent transcription activation complex with afsS promoter
分子名称: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Wang, Y, Zheng, J.
登録日2022-12-27
公開日2023-12-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces.
Plos Biol., 22, 2024
1XBS
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BU of 1xbs by Molmil
Crystal structure of human dim2: a dim1-like protein
分子名称: Dim1-like protein
著者Simeoni, F, Arvai, A, Hopfner, K.-P, Bello, P, Gondeau, C, Heitz, F, Tainer, J, Divita, G.
登録日2004-08-31
公開日2005-08-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical Characterization and Crystal Structure of a Dim1 Family Associated Protein: Dim2
Biochemistry, 44, 2005
4PZD
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BU of 4pzd by Molmil
Crystal structure of (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 in complex with NAD+
分子名称: 3-Hydroxyacyl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kim, J, Chang, J.H, Kim, K.J.
登録日2014-03-29
公開日2015-02-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structure and biochemical properties of the (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 from Ralstonia eutropha
Biochem.Biophys.Res.Commun., 448, 2014
1XD4
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BU of 1xd4 by Molmil
Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
分子名称: Son of sevenless protein homolog 1
著者Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
登録日2004-09-03
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
4Q0C
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BU of 4q0c by Molmil
3.1 A resolution crystal structure of the B. pertussis BvgS periplasmic domain
分子名称: Virulence sensor protein BvgS
著者Dupre, E, Herrou, J, Lensink, M.F, Wintjens, R, Lebedev, A, Crosson, S, Villeret, V, Locht, C, Antoine, R, Jacob-Dubuisson, F.
登録日2014-04-01
公開日2015-02-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Virulence Regulation with Venus Flytrap Domains: Structure and Function of the Periplasmic Moiety of the Sensor-Kinase BvgS.
Plos Pathog., 11, 2015
5F3A
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BU of 5f3a by Molmil
Crystal structure of the bromodomain of human ATAD2 in complex with Compound A14
分子名称: ATPase family AAA domain-containing protein 2, SULFATE ION, ~{N}-(4-ethanoyl-1,3-thiazol-2-yl)azetidin-1-ium-3-carboxamide
著者Dong, J, Caflisch, A.
登録日2015-12-02
公開日2016-12-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Crystal structure of the bromodomain of human ATAD2 in complex with Compound A14
To Be Published
1XK2
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BU of 1xk2 by Molmil
NADPH- and Ascorbate-Supported Heme Oxygenase Reactions are Distinct. Regiospecificity of Heme Cleavage by the R183E Mutant
分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
著者Wang, J, Lad, L, Poulos, T.L, Ortiz de montellano, P.R.
登録日2004-09-26
公開日2004-11-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Regiospecificity determinants of human heme oxygenase: differential NADPH- and ascorbate-dependent heme cleavage by the R183E mutant.
J.Biol.Chem., 280, 2005
8HWA
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BU of 8hwa by Molmil
D5 ATP-ADP-Apo-ssDNA IS1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
1XL5
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BU of 1xl5 by Molmil
HIV-1 Protease in complex with amidhyroxysulfone
分子名称: CHLORIDE ION, N-{(1S)-1-(3-BROMOBENZYL)-4-[(4-BROMOPHENYL)SULFONYL]-6-METHYL-2-OXOHEPTYL}-2-(2,6-DIMETHYLPHENOXY)ACETAMIDE, PROTEASE RETROPEPSIN
著者Boettcher, J, Specker, E, Heine, A, Klebe, G.
登録日2004-09-30
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献An Old Target Revisited: Two New Privileged Skeletons and an Unexpected Binding Mode For HIV-Protease Inhibitors
Angew.Chem.Int.Ed.Engl., 44, 2005
8ILJ
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BU of 8ilj by Molmil
S-formylglutathione hydrolase (BuSFGH) from Burkholderiaceae sp.
分子名称: S-formylglutathione hydrolase
著者Hwang, J, Lee, J.H, Do, H.
登録日2023-03-03
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure and functional characterization of an S-formylglutathione hydrolase (BuSFGH) from Burkholderiaceae sp.
Crystals, 13, 2023
5F0W
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Crystal structure of human copper homeostatic proteins atox1
分子名称: Copper transport protein ATOX1, SILVER ION
著者Wei, W, Wang, F, Zhao, J.
登録日2015-11-28
公開日2017-01-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of tetrasilver bound to human copper homeostatic proteins atox1 at 1.7 Angstroms resolution
To Be Published
1XHD
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X-ray crystal structure of putative acetyltransferase, product of BC4754 gene [Bacillus cereus]
分子名称: SULFATE ION, putative acetyltransferase/acyltransferase
著者Osipiuk, J, Zhou, M, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-09-17
公開日2004-11-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray crystal structure of putative acetyltransferase, product of BC4754 gene from Bacillus cereus.
To be Published
8HWG
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BU of 8hwg by Molmil
D5 ATPrS-ADP-ssDNA form
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
5EV9
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BU of 5ev9 by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED15
分子名称: NITRATE ION, Peregrin, ~{N}-[5-(1~{H}-pyrazol-4-yl)quinolin-8-yl]ethanamide
著者Zhu, J, Caflisch, A.
登録日2015-11-19
公開日2016-06-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
8HWE
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BU of 8hwe by Molmil
Cryo-EM Structure of D5 ATP-ADP form
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8I52
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BU of 8i52 by Molmil
Crystal structure of VIM-2 metallo-beta-lactamase in complex with 10-HHIA
分子名称: (2~{S})-2-butyl-3-methylidene-butanedioic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Wachino, J.
登録日2023-01-23
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of VIM-2 Metallo-beta-lactamase in complex with 10-HHIA
To Be Published
5EVE
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BU of 5eve by Molmil
Crystal structure of Amb a 8 in complex with poly-Pro10
分子名称: Poly-Proline peptide, Profilin
著者Offermann, L.R, Schlachter, C.R, Garrett, J, Chruszcz, M.
登録日2015-11-19
公開日2016-06-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2.
J.Biol.Chem., 291, 2016
1XN2
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BU of 1xn2 by Molmil
New substrate binding pockets for beta-secretase.
分子名称: Beta-secretase 1, OM03-4
著者Turner III, R.T, Hong, L, Koelsch, G, Ghosh, A.K, Tang, J.
登録日2004-10-04
公開日2005-03-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase).
Biochemistry, 44, 2005
1AXV
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BU of 1axv by Molmil
SOLUTION NMR STRUCTURE OF THE [BP]DA ADDUCT OPPOSITE DT IN A DNA DUPLEX, 6 STRUCTURES
分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(CTCTC-[BP]A-CTTCC)D(GGAAGTGAGAG)
著者Mao, B, Gu, Z, Gorin, A.A, Chen, J, Hingerty, B.E, Amid, S, Broyde, S, Geacintov, N.E, Patel, D.J.
登録日1997-10-21
公開日1998-07-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
Biochemistry, 38, 1999
5EX3
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BU of 5ex3 by Molmil
Crystal structure of human SMYD3 in complex with a VEGFR1 peptide
分子名称: ACETIC ACID, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Qiao, Q, Fu, W, Liu, N, Wang, M, Min, J, Zhu, B, Xu, R.M, Yang, N.
登録日2015-11-23
公開日2016-03-09
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.408 Å)
主引用文献Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
J.Biol.Chem., 291, 2016
5EWA
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BU of 5ewa by Molmil
Crystal structure of the metallo-beta-lactamase IMP-1 in complex with the bisthiazolidine inhibitor L-VC26
分子名称: (3~{R},5~{R},7~{a}~{S})-2,2-dimethyl-5-(sulfanylmethyl)-3,5,7,7~{a}-tetrahydro-[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase IMP-1, ...
著者Kosmopoulou, M, Hinchliffe, P, Spencer, J.
登録日2015-11-20
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cross-class metallo-beta-lactamase inhibition by bisthiazolidines reveals multiple binding modes.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EWW
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Crystal structure of the human BRPF1 bromodomain in complex with SEED21
分子名称: NITRATE ION, Peregrin, ~{N}-[(2~{R})-butan-2-yl]-1-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine
著者Zhu, J, Wiedmer, L, Caflisch, A.
登録日2015-11-21
公開日2016-11-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure of the human BRPF1 bromodomain in complex with SEED21
To Be Published
1AWE
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BU of 1awe by Molmil
HUMAN SOS1 PLECKSTRIN HOMOLOGY (PH) DOMAIN, NMR, 20 STRUCTURES
分子名称: SOS1
著者Zheng, J, Cowburn, D.
登録日1997-10-01
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
J.Biol.Chem., 272, 1997
4Q6O
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BU of 4q6o by Molmil
Structural analysis of the mDAP-bound form of Helicobacter pylori Csd4, a D,L-carboxypeptidase
分子名称: 2,6-DIAMINOPIMELIC ACID, CALCIUM ION, Conserved hypothetical secreted protein, ...
著者Kim, H.S, Kim, J, Im, H.N, An, D.R, Lee, M, Hesek, D, Mobashery, S, Kim, J.Y, Cho, K, Yoon, H.J, Han, B.W, Lee, B.I, Suh, S.W.
登録日2014-04-23
公開日2014-11-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structural basis for the recognition of muramyltripeptide by Helicobacter pylori Csd4, a D,L-carboxypeptidase controlling the helical cell shape
Acta Crystallogr.,Sect.D, 70, 2014
1XOY
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Solution structure of At3g04780.1, an Arabidopsis ortholog of the C-terminal domain of human thioredoxin-like protein
分子名称: hypothetical protein At3g04780.1
著者Song, J, Robert, C.T, Lee, M.S, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2004-10-07
公開日2004-10-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein.
Protein Sci., 14, 2005

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件を2024-08-21に公開中

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