1AWE

HUMAN SOS1 PLECKSTRIN HOMOLOGY (PH) DOMAIN, NMR, 20 STRUCTURES

Summary for 1AWE

DescriptorSOS1 (1 entity in total)
Functional Keywordssignal transduction, sos, pleckstrin homology (ph) domain
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight15084.17
Authors
Zheng, J.,Cowburn, D. (deposition date: 1997-10-01, release date: 1998-02-25, Last modification date: 2011-07-13)
Primary citation
Zheng, J.,Chen, R.H.,Corblan-Garcia, S.,Cahill, S.M.,Bar-Sagi, D.,Cowburn, D.
The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
J.Biol.Chem., 272:30340-30344, 1997
PubMed: 9374522 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.272.48.30340
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers9012.3%43.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
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