8Q1U
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![BU of 8q1u by Molmil](/molmil-images/mine/8q1u) | Inward-facing, open1 proteoliposome complex I at 3.3 A, after deactivation treatment. Initially purified in LMNG. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-08-01 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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6VB1
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![BU of 6vb1 by Molmil](/molmil-images/mine/6vb1) | HLA-B*15:02 complexed with a synthetic peptide | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Schutte, R.J, Li, D, Andring, J, McKenna, R, Ostrov, D.A. | 登録日 | 2019-12-18 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | HLA-B*15:02 complexed with a synthetic peptide To Be Published
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8Q1P
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![BU of 8q1p by Molmil](/molmil-images/mine/8q1p) | Inward-facing, open2 proteoliposome complex I at 2.9 A, after deactivation treatment. Initially purified in LMNG. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-08-01 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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8Q48
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![BU of 8q48 by Molmil](/molmil-images/mine/8q48) | Outward-facing, closed proteoliposome complex I at 2.5 A. Initially purified in LMNG. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-08-05 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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6VFQ
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![BU of 6vfq by Molmil](/molmil-images/mine/6vfq) | Crystal structure of monomeric human protocadherin 10 EC1-EC4 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Harrison, O.J, Brasch, J, Shapiro, L. | 登録日 | 2020-01-06 | 公開日 | 2020-03-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins. Cell Rep, 30, 2020
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6VFV
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![BU of 6vfv by Molmil](/molmil-images/mine/6vfv) | Crystal structure of human protocadherin 8 EC5-EC6 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Harrison, O.J, Brasch, J, Shapiro, L. | 登録日 | 2020-01-06 | 公開日 | 2020-03-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins. Cell Rep, 30, 2020
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6ZYA
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![BU of 6zya by Molmil](/molmil-images/mine/6zya) | Extended human uromodulin filament core at 3.5 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R. | 登録日 | 2020-07-31 | 公開日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism. Elife, 9, 2020
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3OJA
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![BU of 3oja by Molmil](/molmil-images/mine/3oja) | Crystal structure of LRIM1/APL1C complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anopheles Plasmodium-responsive Leucine-rich repeat protein 1, ... | 著者 | Baxter, R.H.G, Deisenhofer, J. | 登録日 | 2010-08-20 | 公開日 | 2010-09-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae. Proc.Natl.Acad.Sci.USA, 107, 2010
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8Q45
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![BU of 8q45 by Molmil](/molmil-images/mine/8q45) | Inward-facing, closed proteoliposome complex I at 2.7 A. Initially purified in LMNG. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-08-05 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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7A08
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![BU of 7a08 by Molmil](/molmil-images/mine/7a08) | CryoEM Structure of cGAS Nucleosome complex | 分子名称: | Cyclic GMP-AMP synthase, Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, ... | 著者 | Michalski, S, de Oliveira Mann, C.C, Witte, G, Bartho, J, Lammens, K, Hopfner, K.P. | 登録日 | 2020-08-07 | 公開日 | 2020-09-23 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structural basis for sequestration and autoinhibition of cGAS by chromatin. Nature, 587, 2020
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8Q1Y
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![BU of 8q1y by Molmil](/molmil-images/mine/8q1y) | Outward-facing, open2 proteoliposome complex I at 2.6 A, after deactivation treatment. Initially purified in LMNG. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-08-01 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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8Q0M
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![BU of 8q0m by Molmil](/molmil-images/mine/8q0m) | Outward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-07-28 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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6VGG
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![BU of 6vgg by Molmil](/molmil-images/mine/6vgg) | Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC | 分子名称: | Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... | 著者 | Hou, C, Rohr, J, Tsodikov, O.V. | 登録日 | 2020-01-08 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.31 Å) | 主引用文献 | Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
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8Q0O
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![BU of 8q0o by Molmil](/molmil-images/mine/8q0o) | Outward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-07-28 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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7A5C
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![BU of 7a5c by Molmil](/molmil-images/mine/7a5c) | |
3KA7
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![BU of 3ka7 by Molmil](/molmil-images/mine/3ka7) | Crystal Structure of an oxidoreductase from Methanosarcina mazei. Northeast Structural Genomics Consortium target id MaR208 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Oxidoreductase | 著者 | Seetharaman, J, Su, M, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-18 | 公開日 | 2009-11-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of an oxidoreductase from Methanosarcina mazei To be Published
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8Q49
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![BU of 8q49 by Molmil](/molmil-images/mine/8q49) | Outward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-08-05 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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2JMG
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![BU of 2jmg by Molmil](/molmil-images/mine/2jmg) | Solution structure of V7R mutant of HIV-1 myristoylated matrix protein | 分子名称: | Gag polyprotein, MYRISTIC ACID | 著者 | Saad, J.S, Loeliger, E, Luncsford, P, Liriano, M, Tai, J, Kim, A, Miller, J, Joshi, A, Freed, E.O, Summers, M.F. | 登録日 | 2006-11-11 | 公開日 | 2007-02-06 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Point mutations in the HIV-1 matrix protein turn off the myristyl switch. J.Mol.Biol., 366, 2007
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8Q0F
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![BU of 8q0f by Molmil](/molmil-images/mine/8q0f) | Inward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM. | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Hirst, J. | 登録日 | 2023-07-28 | 公開日 | 2024-06-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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7A62
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![BU of 7a62 by Molmil](/molmil-images/mine/7a62) | Structure of human indoleamine-2,3-dioxygenase 1 (hIDO1) with a complete JK loop | 分子名称: | CHLORIDE ION, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Mirgaux, M, Wouters, J. | 登録日 | 2020-08-24 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.43796444 Å) | 主引用文献 | Influence of the presence of the heme cofactor on the JK-loop structure in indoleamine 2,3-dioxygenase 1. Acta Crystallogr D Struct Biol, 76, 2020
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6VGZ
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![BU of 6vgz by Molmil](/molmil-images/mine/6vgz) | 2.25 A resolution structure of MERS 3CL protease in complex with inhibitor 6d | 分子名称: | N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-({[trans-4-(propan-2-yl)cyclohexyl]oxy}carbonyl)-L-leucinamide, Orf1a protein | 著者 | Lovell, S, Battaile, K.P, Kashipathy, M.M, Rathnayake, A.D, Zheng, J, Kim, Y, Nguyen, H.N, Chang, K.O, Groutas, W.C. | 登録日 | 2020-01-09 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med, 12, 2020
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3SY2
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![BU of 3sy2 by Molmil](/molmil-images/mine/3sy2) | |
8QX9
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![BU of 8qx9 by Molmil](/molmil-images/mine/8qx9) | TDP-43 amyloid fibrils: Morphology-1a | 分子名称: | TAR DNA-binding protein 43 | 著者 | Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. | 登録日 | 2023-10-24 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
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6ZMP
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![BU of 6zmp by Molmil](/molmil-images/mine/6zmp) | |
8QVW
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![BU of 8qvw by Molmil](/molmil-images/mine/8qvw) | Cryo-EM structure of the peptide binding domain of human SRP68/72 | 分子名称: | Signal recognition particle subunit SRP68, Signal recognition particle subunit SRP72 | 著者 | Zhong, Y, Feng, J, Koh, A.F, Kotecha, A, Greber, B.J, Ataide, S.F. | 登録日 | 2023-10-18 | 公開日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of nPBD of human SRP68/72 To Be Published
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