8Q1U
Inward-facing, open1 proteoliposome complex I at 3.3 A, after deactivation treatment. Initially purified in LMNG.
Summary for 8Q1U
| Entry DOI | 10.2210/pdb8q1u/pdb |
| Related | 8Q1P |
| EMDB information | 18066 18067 |
| Descriptor | NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (60 entities in total) |
| Functional Keywords | complex i, oxidoreductase, proteoliposomes, membrane-bound, metabolism, membrane protein |
| Biological source | Bos taurus (cattle) More |
| Total number of polymer chains | 45 |
| Total formula weight | 1096430.94 |
| Authors | Grba, D.N.,Hirst, J. (deposition date: 2023-08-01, release date: 2024-06-05, Last modification date: 2024-06-26) |
| Primary citation | Grba, D.N.,Wright, J.J.,Yin, Z.,Fisher, W.,Hirst, J. Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384:1247-1253, 2024 Cited by PubMed: 38870289DOI: 10.1126/science.ado2075 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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