8DPD
 
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7QPL
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7X9G
 | | Crystal structure of human EDA and EDAR | | 分子名称: | Ectodysplasin-A, secreted form, Tumor necrosis factor receptor superfamily member EDAR | | 著者 | Yu, K, Wan, F, Huang, C, Wu, J, Lei, M. | | 登録日 | 2022-03-15 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants.
Nat Commun, 14, 2023
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5JA0
 | | Crystal structure of human FPPS with allosterically bound FPP | | 分子名称: | FARNESYL DIPHOSPHATE, Farnesyl pyrophosphate synthase, PHOSPHATE ION | | 著者 | Park, J, Zielinski, M, Tsantrizos, Y.S, Berghuis, A.M. | | 登録日 | 2016-04-11 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product.
Nat Commun, 8, 2017
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8DRW
 | | Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp9-nsp10 (C9) cut site sequence | | 分子名称: | DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp9-nsp10 (C9) cut site, PENTAETHYLENE GLYCOL, ... | | 著者 | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | | 登録日 | 2022-07-21 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
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7WVZ
 | | CalA3_modular PKS_KS-AT-DH-KR | | 分子名称: | Beta-ketoacyl-acyl-carrier-protein synthase I | | 著者 | Wang, J, Wang, Z. | | 登録日 | 2022-02-12 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | C-N bond formation by a polyketide synthase.
Nat Commun, 14, 2023
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7QPH
 | | Crystal structure of mouse CARM1 in complex with histone H3_22-31 K27 acetylated | | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, 1,2-ETHANEDIOL, Histone H3 22-31 K27 acetylated, ... | | 著者 | Marechal, N, Cura, V, Troffer-Charlier, N, Bonnefond, L, Cavarelli, J. | | 登録日 | 2022-01-04 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | CARM1 Transition State Mimics
To Be Published
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8DRR
 | | Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp4-nsp5 (C4) cut site sequence | | 分子名称: | 3C-like proteinase nsp5, SODIUM ION | | 著者 | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | | 登録日 | 2022-07-21 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
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2IS9
 | | Structure of yeast DCN-1 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Defective in cullin neddylation protein 1, ... | | 著者 | Yang, X, Zhou, J, Sun, L, Wei, Z, Gao, J, Gong, W, Xu, R.M, Rao, Z, Liu, Y. | | 登録日 | 2006-10-16 | | 公開日 | 2007-06-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural basis for the function of DCN-1 in protein Neddylation.
J.Biol.Chem., 282, 2007
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5JIG
 | | Crytsal structure of Wss1 from S. pombe | | 分子名称: | NICKEL (II) ION, OXYGEN MOLECULE, Ubiquitin and WLM domain-containing metalloprotease SPCC1442.07c | | 著者 | Groll, M, Stingele, J, Boulton, S. | | 登録日 | 2016-04-22 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.
Mol.Cell, 64, 2016
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8E52
 | | MicroED structure of proteinase K recorded on K2 | | 分子名称: | CALCIUM ION, Proteinase K | | 著者 | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Nannenga, B.L, Gonen, T. | | 登録日 | 2022-08-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.8 Å) | | 主引用文献 | Electron-counting MicroED data with the K2 and K3 direct electron detectors.
J.Struct.Biol., 214, 2022
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8TIB
 | | Cryo-EM of tri-pilus from S. islandicus REY15A | | 分子名称: | DUF973 family protein | | 著者 | Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F. | | 登録日 | 2023-07-19 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
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1LJO
 | | CRYSTAL STRUCTURE OF AN SM-LIKE PROTEIN (AF-SM2) FROM ARCHAEOGLOBUS FULGIDUS AT 1.95A RESOLUTION | | 分子名称: | ACETIC ACID, Archaeal Sm-like protein AF-Sm2, CADMIUM ION | | 著者 | Toro, I, Basquin, J, Teo-Dreher, H, Suck, D. | | 登録日 | 2002-04-22 | | 公開日 | 2002-07-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Archaeal Sm proteins form heptameric and hexameric complexes: crystal structures of the Sm1 and Sm2 proteins from the hyperthermophile Archaeoglobus fulgidus.
J.Mol.Biol., 320, 2002
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8DRU
 | | Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence | | 分子名称: | DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp7-nsp8 (C7) cut site, PENTAETHYLENE GLYCOL, ... | | 著者 | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | | 登録日 | 2022-07-21 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
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7QP3
 | | Pseudogymnoascus pannorum M36 protease without the propeptide | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Wilkens, C, Qiu, J, Meyer, A.S, Morth, J.P. | | 登録日 | 2021-12-30 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Phaeosphaeria nodorum M36 protease without the propeptide
To Be Published
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8E53
 | | MicroED structure of proteinase K recorded on K3 | | 分子名称: | CALCIUM ION, Proteinase K | | 著者 | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Nannenga, B.L, Gonen, T. | | 登録日 | 2022-08-19 | | 公開日 | 2022-09-21 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.7 Å) | | 主引用文献 | Electron-counting MicroED data with the K2 and K3 direct electron detectors.
J.Struct.Biol., 214, 2022
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5WFK
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8TIF
 | | Cryo-EM of mono-pilus from S. islandicus REY15A | | 分子名称: | DUF973 family protein | | 著者 | Eastep, G.N, Liu, J, Rich-New, S.T, Egelman, E.H, Krupovic, M, Wang, F. | | 登録日 | 2023-07-19 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Two distinct archaeal type IV pili structures formed by proteins with identical sequence.
Nat Commun, 15, 2024
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5JFN
 | | Crystal structure of Rhodopseudomonas palustris propionaldehyde dehydrogenase with bound CoA and acylated Cys330 | | 分子名称: | Aldehyde dehydrogenase, COENZYME A, PENTAETHYLENE GLYCOL, ... | | 著者 | Zarzycki, J, Sutter, M, Kerfeld, C.A. | | 登録日 | 2016-04-19 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | In Vitro Characterization and Concerted Function of Three Core Enzymes of a Glycyl Radical Enzyme - Associated Bacterial Microcompartment.
Sci Rep, 7, 2017
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5WVX
 | | Crystal Structure of bifunctional Kunitz type Trypsin /amylase inhibitor (AMTIN) from the tubers of Alocasia macrorrhiza | | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CITRIC ACID, Trypsin/chymotrypsin inhibitor | | 著者 | Palayam, M, Radhakrishnan, M, Lakshminarayanan, K, Balu, K.E, Ganapathy, J, Krishnasamy, G. | | 登録日 | 2016-12-29 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | | 主引用文献 | Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition.
Int. J. Biol. Macromol., 113, 2018
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5WMP
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1KGC
 | | Immune Receptor | | 分子名称: | T-cell receptor alpha chain, T-cell receptor beta chain | | 著者 | Kjer-Nielsen, L, Clements, C.S, Brooks, A.G, Purcell, A.W, McCluskey, J, Rossjohn, J. | | 登録日 | 2001-11-26 | | 公開日 | 2002-12-11 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance
STRUCTURE, 10, 2002
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1KQ7
 | | E315Q Mutant Form of Fumarase C from E.coli | | 分子名称: | CITRIC ACID, D-MALATE, FUMARATE HYDRATASE CLASS II | | 著者 | Weaver, T.M, Estevez, M, Skarda, J, Spencer, J. | | 登録日 | 2002-01-04 | | 公開日 | 2002-08-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | X-ray crystallographic and kinetic correlation of a clinically observed human fumarase mutation.
Protein Sci., 11, 2002
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7CX3
 | | Cryo-EM structure of the Taprenepag-bound EP2-Gs complex | | 分子名称: | 2-[3-[[(4-pyrazol-1-ylphenyl)methyl-pyridin-3-ylsulfonyl-amino]methyl]phenoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Qu, C, Mao, C, Xiao, P, Shen, Q, Zhong, Y, Yang, F, Shen, D, Tao, X, Zhang, H, Yan, X, Zhao, R, He, J, Guan, Y, Zhang, C, Hou, G, Zhang, P, Yu, X, Guan, Y, Sun, J, Zhang, Y. | | 登録日 | 2020-09-01 | | 公開日 | 2021-05-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E 2 receptor EP2 subtype.
Sci Adv, 7, 2021
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8DRV
 | | Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp8-nsp9 (C8) cut site sequence | | 分子名称: | Fusion protein of 3C-like proteinase nsp5 and nsp8-nsp9 (C8) cut site, PENTAETHYLENE GLYCOL | | 著者 | Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J. | | 登録日 | 2022-07-21 | | 公開日 | 2022-09-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
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