7X9G

Crystal structure of human EDA and EDAR

Summary for 7X9G

• Entry DOI: 10.2210/pdb7x9g/pdb
• Descriptor: Ectodysplasin-A, secreted form, Tumor necrosis factor receptor superfamily member EDAR (2 entities in total)
• Functional Keywords: ligand-receptor complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 48586.94

Authors

Yu, K.,Wan, F.,Huang, C.,Wu, J.,Lei, M. (deposition date: 2022-03-15, release date: 2023-02-22, Last modification date: 2023-11-29)

• Primary citation: Yu, K.,Huang, C.,Wan, F.,Jiang, C.,Chen, J.,Li, X.,Wang, F.,Wu, J.,Lei, M.,Wu, Y.; Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants.; Nat Commun, 14:767-767, 2023; PubMed: 36765055; DOI: 10.1038/s41467-023-36367-6

Experimental method

X-RAY DIFFRACTION (2.8 Å)