8DRR
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp4-nsp5 (C4) cut site sequence
Summary for 8DRR
| Entry DOI | 10.2210/pdb8drr/pdb |
| Related | 7JOY |
| Descriptor | 3C-like proteinase nsp5, SODIUM ION (3 entities in total) |
| Functional Keywords | viral protease, sars-cov-2, hy, hydrolase |
| Biological source | Severe acute respiratory syndrome coronavirus 2 |
| Total number of polymer chains | 3 |
| Total formula weight | 101343.47 |
| Authors | Lee, J.,Kenward, C.,Worrall, L.J.,Vuckovic, M.,Paetzel, M.,Strynadka, N.C.J. (deposition date: 2022-07-21, release date: 2022-09-21, Last modification date: 2023-10-18) |
| Primary citation | Lee, J.,Kenward, C.,Worrall, L.J.,Vuckovic, M.,Gentile, F.,Ton, A.T.,Ng, M.,Cherkasov, A.,Strynadka, N.C.J.,Paetzel, M. X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nat Commun, 13:5196-5196, 2022 Cited by PubMed: 36057636DOI: 10.1038/s41467-022-32854-4 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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