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PDB: 42706 件

6OII
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Structure of Aedes aegypti OBP22 in the complex with arachidonic acid
分子名称: 1,2-ETHANEDIOL, AAEL005772-PA, ARACHIDONIC ACID, ...
著者Jones, D.N, Wang, J.
登録日2019-04-09
公開日2019-05-08
最終更新日2020-05-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Aedes aegypti Odorant Binding Protein 22 selectively binds fatty acids through a conformational change in its C-terminal tail.
Sci Rep, 10, 2020
1JF2
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Crystal Structure of W92F obelin mutant from Obelia longissima at 1.72 Angstrom resolution
分子名称: C2-HYDROPEROXY-COELENTERAZINE, obelin
著者Liu, Z.-J, Vysotski, E.S, Deng, L, Markova, S.V, Lee, J, Rose, J.P, Wang, B.-C.
登録日2001-06-19
公開日2001-07-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Violet bioluminescence and fast kinetics from W92F obelin: structure-based proposals for the bioluminescence triggering and the identification of the emitting species.
Biochemistry, 42, 2003
6LJI
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X-ray structure of synthetic GB1 domain with mutations K10(DVA), T11V
分子名称: Immunoglobulin G-binding protein G
著者Penmatsa, A, Chatterjee, J, Majumder, P, Khatri, B.
登録日2019-12-16
公開日2020-08-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.843 Å)
主引用文献Increasing protein stability by engineering the n -> pi * interaction at the beta-turn.
Chem Sci, 11, 2020
6ORL
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BU of 6orl by Molmil
RF1 pre-accommodated 70S complex at 24 ms
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
登録日2019-04-30
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OU9
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Asymmetric focused reconstruction of human norovirus GI.7 Houston strain VLP asymmetric unit in T=3 symmetry
分子名称: Major capsid protein
著者Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
登録日2019-05-04
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OUT
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BU of 6out by Molmil
Asymmetric focused reconstruction of human norovirus GI.1 Norwalk strain VLP asymmetric unit in T=3 symmetry
分子名称: Capsid protein VP1
著者Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L.
登録日2019-05-05
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
5ZM5
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BU of 5zm5 by Molmil
Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution
分子名称: CHOLESTEROL, Oxysterol-binding protein-related protein 1
著者Dong, J, Wang, J, Wu, J.W.
登録日2018-04-01
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
6ODD
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BU of 6odd by Molmil
Crystal structure of the human complex ACP-ISD11
分子名称: Acyl carrier protein, mitochondrial, CALCIUM ION, ...
著者Herrera, M.G, Noguera, M.E, Klinke, S, Santos, J.
登録日2019-03-26
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Human ACP-ISD11 Heterodimer.
Biochemistry, 58, 2019
6LDF
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Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96K AB5
分子名称: CHLORIDE ION, HEME C, ZINC ION, ...
著者Song, W.J, Yu, J.
登録日2019-11-21
公開日2021-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021
2Y0C
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BceC mutation Y10S
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ...
著者Rocha, J, Popescu, A.O, Borges, P, Mil-Homens, D, Sa-Correia, I, Fialho, A.M, Frazao, C.
登録日2010-12-02
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of Burkholderia Cepacia Udp-Glucose Dehydrogenase (Ugd) Bcec and Role of Tyr10 in Final Hydrolysis of Ugd Thioester Intermediate.
J.Bacteriol., 193, 2011
3CJ5
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BU of 3cj5 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide, RNA-directed RNA polymerase
著者Hendle, j.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
6LDE
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BU of 6lde by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96V AB5
分子名称: CHLORIDE ION, HEME C, ZINC ION, ...
著者Song, W.J, Yu, J.
登録日2019-11-21
公開日2021-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021
6LDG
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BU of 6ldg by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96I AB5
分子名称: CHLORIDE ION, HEME C, MAGNESIUM ION, ...
著者Song, W.J, Yu, J.
登録日2019-11-21
公開日2021-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021
2J8Z
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BU of 2j8z by Molmil
Crystal Structure of human P53 inducible oxidoreductase (TP53I3,PIG3)
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, QUINONE OXIDOREDUCTASE
著者Pike, A.C.W, Shafqat, N, Debreczeni, J, Johansson, C, Haroniti, A, Gileadi, O, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, von Delft, F, Porte, S, Fita, I, Pares, J, Pares, X, Oppermann, U.
登録日2006-10-31
公開日2006-11-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-Dimensional Structure and Enzymatic Function of Proapoptotic Human P53-Inducible Quinone Oxidoreductase Pig3.
J.Biol.Chem., 284, 2009
6OF8
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BU of 6of8 by Molmil
Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CamKII-alpha hub domain
分子名称: Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, POTASSIUM ION
著者McSpadden, E.D, Chi, C.C, Gee, C.L, Kuriyan, J.
登録日2019-03-28
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Variation in assembly stoichiometry in non-metazoan homologs of the hub domain of Ca2+/calmodulin-dependent protein kinase II.
Protein Sci., 28, 2019
5ZO2
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BU of 5zo2 by Molmil
Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain in complex with mouse nectin-like molecule 1 (mNecl-1) Ig1 domain, 3.3A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 3, Cell adhesion molecule 4
著者Liu, X, An, T, Li, D, Fan, Z, Xiang, P, Li, C, Ju, W, Li, J, Hu, G, Qin, B, Yin, B, Wojdyla, J.A, Wang, M, Yuan, J, Qiang, B, Shu, P, Cui, S, Peng, X.
登録日2018-04-12
公開日2019-01-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8B70
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BU of 8b70 by Molmil
KimA from B. subtilis with nucleotide second-messenger c-di-AMP bound
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ...
著者Vonck, J, Wieferig, J.P.
登録日2022-09-28
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cyclic di-AMP traps proton-coupled K + transporters of the KUP family in an inward-occluded conformation.
Nat Commun, 14, 2023
4O7H
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BU of 4o7h by Molmil
Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460
分子名称: Glutathione S-transferase
著者Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Attonito, J.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2013-12-24
公開日2014-01-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460
TO BE PUBLISHED
2NY2
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HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ...
著者Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
登録日2006-11-20
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
8PK4
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Cryo EM structure of the type 5A polymorph of alpha-synuclein.
分子名称: Alpha-synuclein
著者Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R.
登録日2023-06-24
公開日2024-05-29
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation.
Elife, 12, 2024
6I7O
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The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition.
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Cheng, J, Becker, T, Beckmann, R.
登録日2018-11-16
公開日2019-01-16
最終更新日2019-03-13
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
8B71
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Upright KimA dimer with bound c-di-AMP from B. subtilis
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Potassium transporter KimA
著者Vonck, J, Wieferig, J.P.
登録日2022-09-28
公開日2023-01-18
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cyclic di-AMP traps proton-coupled K + transporters of the KUP family in an inward-occluded conformation.
Nat Commun, 14, 2023
4P0E
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YhdE E33A (p212121 space group)
分子名称: Maf-like protein YhdE, PHOSPHATE ION, SULFATE ION
著者Jia, Z, Zheng, J, Jin, J, Wang, N.
登録日2014-02-20
公開日2014-04-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献YhdE E33A
To Be Published
6ONT
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Structure of the Francisella response regulator 1452 receiver domain
分子名称: CALCIUM ION, CHLORIDE ION, SODIUM ION, ...
著者Milton, M.E, Cavanagh, J.
登録日2019-04-22
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Francisella novicidaTwo-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production.
Front Cell Infect Microbiol, 10, 2020
4O6F
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Structural Basis of Estrogen Receptor Alpha Methylation Mediated by Histone Methyltransferase SmyD2
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Estrogen receptor, N-lysine methyltransferase SMYD2, ...
著者Jiang, Y, Trescott, L, Holcomb, J, Brunzelle, J, Sirinupong, N, Shi, X, Yang, Z.
登録日2013-12-20
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Structural Insights into Estrogen Receptor alpha Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation.
J.Mol.Biol., 426, 2014

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