6PA2
 
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5WOF
 | | 1.65 ANGSTROM STRUCTURE OF THE DYNEIN LIGHT CHAIN 1 FROM PLASMODIUM FALCIPARUM | | 分子名称: | Dynein light chain 1, putative | | 著者 | Walker, J.R, Lew, J, Amani, M, Alam, Z, Wasney, G, Boulanger, K, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Hui, R, Botchkarev, A, Vedadi, M, Structural Genomics Consortium (SGC) | | 登録日 | 2017-08-02 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Genome-scale Protein Expression and Structural Biology of
Plasmodium Falciparum and Related Apicomplexan Organisms.
MOL.BIOCHEM.PARASITOL., 151, 2007
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6BMB
 | | Crystal structure of Arabidopsis Dehydroquinate dehydratase-shikimate dehydrogenase (T381G mutant) in complex with tartrate and shikimate | | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic, ... | | 著者 | Christendat, D, Peek, J. | | 登録日 | 2017-11-14 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.077 Å) | | 主引用文献 | Structural and biochemical approaches uncover multiple evolutionary trajectories of plant quinate dehydrogenases.
Plant J., 2018
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8IDB
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7NYY
 | | Cryo-EM structure of the MukBEF monomer | | 分子名称: | 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ... | | 著者 | Buermann, F, Lowe, J. | | 登録日 | 2021-03-23 | | 公開日 | 2021-07-07 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.
Mol.Cell, 81, 2021
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7NZ4
 | | Cryo-EM structure of the MukBEF dimer | | 分子名称: | 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Chromosome partition protein MukB, ... | | 著者 | Buermann, F, Lowe, J. | | 登録日 | 2021-03-23 | | 公開日 | 2021-07-07 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (13 Å) | | 主引用文献 | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.
Mol.Cell, 81, 2021
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7NYX
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7NW2
 | | Crystal Structure of SARS-CoV-2 main protease in complex with LON-WEI-adc59df6-47 | | 分子名称: | 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Fearon, D, Douangamath, A, Aimon, A, Brandao-Neto, J, Dias, A, Dunnett, L, Gehrtz, P, Gorrie-Stone, T.J, Lukacik, P, Powell, A.J, Skyner, R, Strain-Damerell, C.M, Zaidman, D, London, N, Walsh, M.A, von Delft, F, Covid Moonshot Consortium | | 登録日 | 2021-03-16 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 M pro inhibitor.
Cell Chem Biol, 28, 2021
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2V11
 | | Crystal Structure of Renin with Inhibitor 6 | | 分子名称: | (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE, RENIN | | 著者 | Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G. | | 登録日 | 2007-05-21 | | 公開日 | 2007-07-03 | | 最終更新日 | 2019-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
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6PA4
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7NZ2
 | | Cryo-EM structure of the MukBEF-MatP-DNA tetrad | | 分子名称: | 4'-PHOSPHOPANTETHEINE, ADENOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | | 著者 | Buermann, F, Lowe, J. | | 登録日 | 2021-03-23 | | 公開日 | 2021-07-07 | | 最終更新日 | 2022-06-29 | | 実験手法 | ELECTRON MICROSCOPY (11 Å) | | 主引用文献 | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.
Mol.Cell, 81, 2021
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6N4Q
 | | CryoEM structure of Nav1.7 VSD2 (actived state) in complex with the gating modifier toxin ProTx2 | | 分子名称: | Beta/omega-theraphotoxin-Tp2a, Fab heavy chain, Fab light chain, ... | | 著者 | Xu, H, Rohou, A, Arthur, C.P, Estevez, A, Ciferri, C, Payandeh, J, Koth, C.M. | | 登録日 | 2018-11-20 | | 公開日 | 2019-01-23 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.
Cell, 176, 2019
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7NYW
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7NYZ
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7NZ0
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7NZ3
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7WNH
 | | Crystal structure of Nurr1 binding to NBRE | | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), Nuclear receptor subfamily 4 group A member 2, ... | | 著者 | Zhao, M, Xu, T, Wang, N, Guo, Y, Liu, J. | | 登録日 | 2022-01-18 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXR alpha heterodimer.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8API
 | | THE S VARIANT OF HUMAN ALPHA1-ANTITRYPSIN, STRUCTURE AND IMPLICATIONS FOR FUNCTION AND METABOLISM | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-1 ANTITRYPSIN (CHAIN A), ... | | 著者 | Loebermann, H, Tokuoka, R, Deisenhofer, J, Huber, R. | | 登録日 | 1988-09-08 | | 公開日 | 1990-10-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism.
Protein Eng., 2, 1989
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2C46
 | | CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase | | 分子名称: | MRNA CAPPING ENZYME | | 著者 | Debreczeni, J, Johansson, C, Longman, E, Gileadi, O, SavitskySmee, P, Smee, C, Bunkoczi, G, Ugochukwu, E, von Delft, F, Sundstrom, M, Weigelt, J, Arrowsmith, C, Edwards, A, Knapp, S. | | 登録日 | 2005-10-15 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of the Human RNA Guanylyltransferase and 5'-Phosphatase
To be Published
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7WQV
 | | Crystal structure of a neutralizing monoclonal antibody (Ab08) in complex with SARS-CoV-2 receptor-binding domain (RBD) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab08, ... | | 著者 | Zha, J, Meng, L, Zhang, X, Li, D. | | 登録日 | 2022-01-26 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy.
Plos Pathog., 19, 2023
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8I9Q
 | | The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state | | 分子名称: | Phosducin-like protein 3, T-complex protein 1 subunit delta | | 著者 | Roh, S.H, Park, J, Kim, H, Lim, S. | | 登録日 | 2023-02-07 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | | 主引用文献 | A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle.
Nat Commun, 15, 2024
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2BL4
 | | Lactaldehyde:1,2-propanediol oxidoreductase of Escherichia coli | | 分子名称: | CHLORIDE ION, FE (II) ION, LACTALDEHYDE REDUCTASE, ... | | 著者 | Montella, C, Bellsolell, L, Perez-Luque, R, Badia, J, Baldoma, L, Coll, M, Aguilar, J. | | 登録日 | 2005-03-01 | | 公開日 | 2005-07-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal Structure of an Iron-Dependent Group III Dehydrogenase that Interconverts L-Lactaldehyde and L-1,2-Propanediol in Escherichia Coli.
J.Bacteriol., 187, 2005
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4LKG
 | | The structure of hemagglutinin from a avian-origin H7N9 influenza virus (A/Shanghai/1/2013) in complex with avian receptor analog 3'SLNLN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-07-07 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses
Science, 342, 2013
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6C6A
 | | Structure of glycolipid aGSA[16,6P] in complex with mouse CD1d | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Zajonc, D.M, Wang, J. | | 登録日 | 2018-01-18 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
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6G75
 | | Crystal structure of the common ancestor of haloalkane dehalogenases and Renilla luciferase (AncHLD-RLuc) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Common ancestor of haloalkane dehalogenase and Renilla luciferase (AncHLD-RLuc), ... | | 著者 | Chaloupkova, R, Waterman, J, Marek, M, Damborsky, J. | | 登録日 | 2018-04-04 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.391 Å) | | 主引用文献 | Light-Emitting Dehalogenases: Reconstruction of Multifunctional Biocatalysts
Acs Catalysis, 2019
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