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PDB: 42550 results

5FWR
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Breaking down the wall: mutation of the tyrosine gate of the universal Escherichia coli fimbrial adhesin FimH
Descriptor: FimH, biphenyl-4-yl alpha-D-mannopyranoside
Authors:Bouckaert, J.
Deposit date:2016-02-21
Release date:2016-11-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.
IUCrJ, 4, 2017
1XM6
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Catalytic Domain Of Human Phosphodiesterase 4B In Complex With (R)-Mesopram
Descriptor: (5R)-5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-oxazolidin-2-one, MAGNESIUM ION, ZINC ION, ...
Authors:Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-10-01
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
8GQJ
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BU of 8gqj by Molmil
Structure of Thiolase from Pseudomonas aeruginosa PAO1
Descriptor: GLYCEROL, NONAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ...
Authors:Hong, J, Son, H.F, Kim, K.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
4PV4
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Proline aminopeptidase P II from Yersinia pestis
Descriptor: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ...
Authors:Osipiuk, J, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-03-14
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Proline aminopeptidase P II from Yersinia pestis
To be Published
8GQF
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BU of 8gqf by Molmil
Crystal structure of Thiolase
Descriptor: GLYCEROL, Thiolase
Authors:Hong, J, Son, H.F, Kim, K.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
5FAK
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Crystal structure of Double Mutant S12T and N87T of Adenosine/Methylthioadenosine Phosphorylase from Schistosoma mansoni in complex with Adenine
Descriptor: ADENINE, Methylthioadenosine phosphorylase, SULFATE ION
Authors:Torini, J.R, Brandao-Neto, J, DeMarco, R, Pereira, H.M.
Deposit date:2015-12-11
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.
PLoS Negl Trop Dis, 10, 2016
4R96
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Structure of a Llama Glama Fab 48A2 against human cMet
Descriptor: Llama glama Fab 48A2 against human cMet H chain, Llama glama Fab 48A2 against human cMet L chain
Authors:Klarenbeek, A, El Mazouari, K, Desmyter, A, Blanchetot, C, Hultberg, A, Roovers, R.C, Cambillau, C, Spinelli, S, Del-Favero, J, Verrips, T, de Haard, H, Achour, I.
Deposit date:2014-09-03
Release date:2015-06-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.
MAbs, 7, 2015
5FR7
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BU of 5fr7 by Molmil
Erwinia amylovora AmyR amylovoran repressor, a member of the YbjN protein family
Descriptor: AMYR
Authors:Bartho, J.D, Bellini, D, Wuerges, J, Demitri, N, Walsh, M, Benini, S.
Deposit date:2015-12-16
Release date:2017-01-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of Erwinia amylovora AmyR, a member of the YbjN protein family, shows similarity to type III secretion chaperones but suggests different cellular functions.
PLoS ONE, 12, 2017
8GQH
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Structure of Thiolase from Pseudomonas aeruginosa PAO1
Descriptor: GLYCEROL, Thiolase
Authors:Hong, J, Son, H.F, Kim, K.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQN
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X-ray structure of thiolase with CoA
Descriptor: COENZYME A, Thiolase
Authors:Hong, J, Son, H.F, Kim, K.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8GQL
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BU of 8gql by Molmil
X-ray structure of Thiolase from Pseudomonas aeruginosa PAO1
Descriptor: GLYCEROL, Thiolase
Authors:Hong, J, Son, H.F, Kim, K.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
5G0A
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BU of 5g0a by Molmil
The crystal structure of a S-selective transaminase from Bacillus megaterium
Descriptor: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W.
Deposit date:2016-03-17
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases
Biochemistry, 55, 2016
1XOR
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BU of 1xor by Molmil
Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Zardaverine
Descriptor: 6-(4-DIFLUOROMETHOXY-3-METHOXY-PHENYL)-2H-PYRIDAZIN-3-ONE, MAGNESIUM ION, ZINC ION, ...
Authors:Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J.
Deposit date:2004-10-06
Release date:2004-12-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12, 2004
1X7A
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Porcine Factor IXa Complexed to 1-{3-[amino(imino)methyl]phenyl}-N-[4-(1H-benzimidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
Descriptor: 1-{3-[AMINO(IMINO)METHYL]PHENYL}-N-[4-(1H-BENZIMIDAZOL-1-YL)-2-FLUOROPHENYL]-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE, Coagulation Factor IX, light chain, ...
Authors:Alexander, R.S, Smallwood, A.M, Smallheer, J.M, Wang, J, Wang, S, Nakajima, S, Rossi, K.A, Barbera, F, Burdick, D, Luettgen, J.M.
Deposit date:2004-08-13
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa
Bioorg.Med.Chem.Lett., 14, 2004
8GQG
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Crystal structure of Thioloase from Pseudomonas aeruginosa PAO1
Descriptor: Thiolase
Authors:Hong, J, Son, H.F, Kim, K.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of thiolase from Pseudomonas aeruginosa PAO1
To Be Published
8G91
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LaM domain of human LARP1 in complex with Rp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
8G90
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LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
4QPK
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1.7 Angstrom Structure of a Bacterial Phosphotransferase
Descriptor: GLYCEROL, PHOSPHATE ION, PHOSPHOTRANSFERASE, ...
Authors:Willett, J.W, Crosson, S, Herrou, J.
Deposit date:2014-06-23
Release date:2015-07-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen.
Proc.Natl.Acad.Sci.USA, 112, 2015
1XAI
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BU of 1xai by Molmil
CRYSTAL STRUCTURE OF STAPHLYOCOCCUS AUREUS 3-DEHYDROQUINATE SYNTHASE (DHQS) IN COMPLEX WITH ZN2+, NAD+ AND CARBAPHOSPHONATE
Descriptor: 3-dehydroquinate synthase, ZINC ION, [1R-(1ALPHA,3BETA,4ALPHA,5BETA)]-5-(PHOSPHONOMETHYL)-1,3,4-TRIHYDROXYCYCLOHEXANE-1-CARBOXYLIC ACID
Authors:Nichols, C.E, Ren, J, Leslie, K, Dhaliwal, B, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K.
Deposit date:2004-08-25
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of ligand induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases.
J.Mol.Biol., 343, 2004
8GIS
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BU of 8gis by Molmil
Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.5mM Mn2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-03-14
Release date:2024-04-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
1A5T
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BU of 1a5t by Molmil
CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III
Descriptor: DELTA PRIME, ZINC ION
Authors:Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J.
Deposit date:1998-02-18
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Cell(Cambridge,Mass.), 91, 1997
8GIR
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BU of 8gir by Molmil
Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.2mM Mn2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-03-14
Release date:2024-04-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
8GIO
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BU of 8gio by Molmil
Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.1mM Mn2+
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ...
Authors:Wu, S, Sohn, J.
Deposit date:2023-03-14
Release date:2024-04-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS.
Nat Commun, 15, 2024
3MW6
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Crystal structure of NMB1681 from Neisseria meningitidis MC58, a FinO-like RNA chaperone
Descriptor: GLYCEROL, uncharacterized protein NMB1681
Authors:Tan, K, Zhou, M, Duggan, E, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-05
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:N. meningitidis 1681 is a member of the FinO family of RNA chaperones.
Rna Biol., 7, 2010
1XU8
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The 2.8 A structure of a tumour suppressing serpin
Descriptor: Maspin, SULFATE ION
Authors:Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C.
Deposit date:2004-10-25
Release date:2005-03-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005

224004

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