5WE4
 
 | | 70S ribosome-EF-Tu wt complex with GppNHp | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Fislage, M, Brown, Z, Frank, J. | | Deposit date: | 2017-07-07 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
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3CEY
 | | Crystal structure of L3MBTL2 | | Descriptor: | Lethal(3)malignant brain tumor-like 2 protein | | Authors: | Nady, N, Guo, Y, Pan, P, Allali-Hassani, A, Qi, C, Zhu, H, Dong, A, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Edwards, A.M, Weigelt, J, Bountra, C, Arrowsmith, C.H, Bochkarev, A, Read, R, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-02-29 | | Release date: | 2008-05-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2.
Nucleic Acids Res., 37, 2009
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5WJL
 | | Crystal Structure of HLA-A*11:01 with GTS1 peptide | | Descriptor: | Beta-2-microglobulin, CHLORIDE ION, GTS1 peptide, ... | | Authors: | Gras, S, Rossjohn, J. | | Deposit date: | 2017-07-23 | | Release date: | 2017-09-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Nat. Immunol., 18, 2017
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5WZ1
 | | Crystal structure of Zika virus NS5 methyltransferase bound to S-adenosyl-L-methionine | | Descriptor: | NS5 methyltransferase, S-ADENOSYLMETHIONINE | | Authors: | Duan, W, Song, H, Qi, J, Shi, Y, Gao, G.F. | | Deposit date: | 2017-01-16 | | Release date: | 2017-03-08 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.507 Å) | | Cite: | The crystal structure of Zika virus NS5 reveals conserved drug targets.
EMBO J., 36, 2017
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5WMQ
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6GW9
 | | Concanavalin A structure determined with data from the EuXFEL, the first MHz free electron laser | | Descriptor: | CALCIUM ION, Concanavalin V, MAGNESIUM ION | | Authors: | Gruenbein, M.L, Gorel, A, Stricker, M, Bean, R, Bielecki, J, Doerner, K, Hartmann, E, Hilpert, M, Kloos, M, Letrun, R, Sztuk-Dambietz, J, Mancuso, A, Meserschmidt, M, Nass-Kovacs, G, Ramilli, M, Roome, C.M, Sato, T, Doak, R.B, Shoeman, R.L, Foucar, L, Colletier, J.P, Barends, T.R.M, Stan, C, Schlichting, I. | | Deposit date: | 2018-06-22 | | Release date: | 2018-09-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Megahertz data collection from protein microcrystals at an X-ray free-electron laser.
Nat Commun, 9, 2018
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3CXN
 | | Structure of the Urease Accessory Protein UreF from Helicobacter pylori | | Descriptor: | GLYCEROL, Urease accessory protein ureF | | Authors: | Lam, R, Johns, K, Romanov, V, Dong, A, Wu-Brown, J, Guthrie, J, Dharamsi, A, Thambipillai, D, Mansoury, K, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. | | Deposit date: | 2008-04-24 | | Release date: | 2009-05-12 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of a truncated urease accessory protein UreF from Helicobacter pylori.
Proteins, 78, 2010
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5WZH
 | | Structure of APUM23-GGAAUUGACGG | | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | | Authors: | Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y. | | Deposit date: | 2017-01-18 | | Release date: | 2017-09-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.509 Å) | | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
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4US2
 | | The crystal structure of H-Ras and SOS in complex with ligands | | Descriptor: | 3-[(3R)-1-ethyl-2,5-dioxopyrrolidin-3-yl]benzamide, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 | | Authors: | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | | Deposit date: | 2014-07-02 | | Release date: | 2015-03-04 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation.
J.Med.Chem., 58, 2015
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4V69
 | | Ternary complex-bound E.coli 70S ribosome. | | Descriptor: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J. | | Deposit date: | 2008-12-11 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (6.7 Å) | | Cite: | Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
Proc.Natl.Acad.Sci.USA, 106, 2009
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4GP3
 | | The crystal structure of human fascin 1 K358A mutant | | Descriptor: | BROMIDE ION, CHLORIDE ION, Fascin, ... | | Authors: | Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y. | | Deposit date: | 2012-08-20 | | Release date: | 2012-11-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
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3VFO
 | | crystal structure of HLA B*3508 LPEP157A, HLA mutant Ala157 | | Descriptor: | Beta-2-microglobulin, LPEP peptide from EBV, LPEPLPQGQLTAY, ... | | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | | Deposit date: | 2012-01-10 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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6GWA
 | | Concanavalin B structure determined with data from the EuXFEL, the first MHz free electron laser | | Descriptor: | Concanavalin B | | Authors: | Gruenbein, M.L, Gorel, A, Stricker, M, Bean, R, Bielecki, J, Doerner, K, Hartmann, E, Hilpert, M, Kloos, M, Letrun, R, Sztuk-Dambietz, J, Mancuso, A, Meserschmidt, M, Nass-Kovacs, G, Ramilli, M, Roome, C.M, Sato, T, Doak, R.B, Shoeman, R.L, Foucar, L, Colletier, J.P, Barends, T.R.M, Stan, C, Schlichting, I. | | Deposit date: | 2018-06-22 | | Release date: | 2018-09-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Megahertz data collection from protein microcrystals at an X-ray free-electron laser.
Nat Commun, 9, 2018
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4GP0
 | | The crystal structure of human fascin 1 R149A K150A R151A mutant | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, ... | | Authors: | Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y. | | Deposit date: | 2012-08-20 | | Release date: | 2012-11-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
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4H5S
 | | Complex structure of Necl-2 and CRTAM | | Descriptor: | Cell adhesion molecule 1, Cytotoxic and regulatory T-cell molecule | | Authors: | Zhang, S, Lu, G, Qi, J, Li, Y, Zhang, Z, Zhang, B, Yan, J, Gao, G.F. | | Deposit date: | 2012-09-18 | | Release date: | 2013-08-07 | | Last modified: | 2022-08-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Competition of cell adhesion and immune recognition: insights into the interaction between CRTAM and nectin-like 2.
Structure, 21, 2013
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7X6I
 | | Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class1 | | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Won, J, Jeong, H, Lee, H.H. | | Deposit date: | 2022-03-07 | | Release date: | 2023-04-26 | | Last modified: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.93 Å) | | Cite: | Molecular architecture of the G alpha i -bound TRPC5 ion channel.
Nat Commun, 14, 2023
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3VFM
 | | crystal structure of HLA B*3508 LPEP155A, HLA mutant Ala155 | | Descriptor: | Beta-2-microglobulin, LPEP peptide from EBV, LPEPLPQGQLTAY, ... | | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | | Deposit date: | 2012-01-10 | | Release date: | 2012-03-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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3VRI
 | | HLA-B*57:01-RVAQLENVYI in complex with abacavir | | Descriptor: | 10-mer peptide, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Vivian, J.P, Illing, P.T, McCluskey, J, Rossjohn, J. | | Deposit date: | 2012-04-11 | | Release date: | 2012-05-30 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
Nature, 486, 2012
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7X6C
 | | Cryo-EM structure of the human TRPC5 ion channel in lipid nanodiscs, class1 | | Descriptor: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ... | | Authors: | Won, J, Jeong, H, Lee, H.H. | | Deposit date: | 2022-03-07 | | Release date: | 2023-05-24 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Molecular architecture of the G alpha i -bound TRPC5 ion channel.
Nat Commun, 14, 2023
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3W28
 | | The high-resolution crystal structure of TsXylA, intracellular xylanase from /Thermoanaerobacterium saccharolyticum JW/SL-YS485/: the complex of the E251A mutant with xylotriose | | Descriptor: | Glycoside hydrolase family 10, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose | | Authors: | Han, X, Gao, J, Shang, N, Huang, C.-H, Ko, T.-P, Zhu, Z, Wiegel, J, Shao, W, Guo, R.-T. | | Deposit date: | 2012-11-27 | | Release date: | 2013-04-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Structural and functional analyses of catalytic domain of GH10 xylanase from Thermoanaerobacterium saccharolyticum JW/SL-YS485
Proteins, 81, 2013
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3W21
 | | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase in complex with alpha-KG from Burkholderia ambifaria AMMD | | Descriptor: | 2-OXOGLUTARIC ACID, Putative uncharacterized protein, ZINC ION | | Authors: | Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. | | Deposit date: | 2012-11-26 | | Release date: | 2013-07-17 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD
Plos One, 8, 2013
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1WWC
 | | NT3 BINDING DOMAIN OF HUMAN TRKC RECEPTOR | | Descriptor: | PROTEIN (NT-3 GROWTH FACTOR RECEPTOR TRKC) | | Authors: | Ultsch, M.H, Wiesmann, C, Simmons, L.C, Henrich, J, Yang, M, Reilly, D, Bass, S.H, De Vos, A.M. | | Deposit date: | 1999-04-30 | | Release date: | 1999-07-07 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC.
J.Mol.Biol., 290, 1999
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6ZCE
 | | Structure of a yeast ABCE1-bound 43S pre-initiation complex | | Descriptor: | 18S ribosomal RNA (1719-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | Authors: | Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | | Deposit date: | 2020-06-10 | | Release date: | 2020-10-07 | | Last modified: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (5.3 Å) | | Cite: | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
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6ZIX
 | | Structure of RcsB from Salmonella enterica serovar Typhimurium bound to promoter P1flhDC in the presence of phosphomimetic BeF3- | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P1flhDC promoter sequence of 23 bp, ... | | Authors: | Huesa, J, Marina, A, Casino, P. | | Deposit date: | 2020-06-26 | | Release date: | 2021-02-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon.
Nucleic Acids Res., 49, 2021
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6ZIL
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