3VRI
HLA-B*57:01-RVAQLENVYI in complex with abacavir
Summary for 3VRI
Entry DOI | 10.2210/pdb3vri/pdb |
Related | 3VRJ |
Descriptor | HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, 10-mer peptide, ... (6 entities in total) |
Functional Keywords | human leukocyte antigen, antigen presentation, immune system, t-cell receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P18465 Secreted: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 45217.33 |
Authors | Vivian, J.P.,Illing, P.T.,McCluskey, J.,Rossjohn, J. (deposition date: 2012-04-11, release date: 2012-05-30, Last modification date: 2023-11-08) |
Primary citation | Illing, P.T.,Vivian, J.P.,Dudek, N.L.,Kostenko, L.,Chen, Z.,Bharadwaj, M.,Miles, J.J.,Kjer-Nielsen, L.,Gras, S.,Williamson, N.A.,Burrows, S.R.,Purcell, A.W.,Rossjohn, J.,McCluskey, J. Immune self-reactivity triggered by drug-modified HLA-peptide repertoire Nature, 486:554-558, 2012 Cited by PubMed: 22722860DOI: 10.1038/nature11147 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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