1X05
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![BU of 1x05 by Molmil](/molmil-images/mine/1x05) | Solution structure of the C-terminal PH domain of human pleckstrin | 分子名称: | Pleckstrin | 著者 | Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-03-15 | 公開日 | 2005-09-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the C-terminal PH domain of human pleckstrin To be Published
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5XPR
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![BU of 5xpr by Molmil](/molmil-images/mine/5xpr) | Human endothelin receptor type-B in complex with antagonist bosentan | 分子名称: | 4-tert-butyl-N-[6-(2-hydroxyethyloxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]benzenesulfonamide, Endothelin B receptor,Endolysin,Endothelin B receptor, SULFATE ION | 著者 | Shihoya, W, Nishizawa, T, Yamashita, K, Hirata, K, Okuta, A, Tani, K, Fujiyoshi, Y, Doi, T, Nureki, O. | 登録日 | 2017-06-04 | 公開日 | 2017-08-16 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog Nat. Struct. Mol. Biol., 24, 2017
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1WH9
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![BU of 1wh9 by Molmil](/molmil-images/mine/1wh9) | Solution structure of the KH domain of human ribosomal protein S3 | 分子名称: | 40S ribosomal protein S3 | 著者 | Nameki, N, Tomizawa, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-05-28 | 公開日 | 2004-11-28 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the KH domain of human ribosomal protein S3 To be Published
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7VTI
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![BU of 7vti by Molmil](/molmil-images/mine/7vti) | Crystal structure of the Cas13bt3-crRNA binary complex | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... | 著者 | Nakagawa, R, Takeda, N.S, Tomita, A, Hirano, H, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | 登録日 | 2021-10-29 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structure and engineering of the minimal type VI CRISPR-Cas13bt3. Mol.Cell, 82, 2022
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7V73
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![BU of 7v73 by Molmil](/molmil-images/mine/7v73) | Thermostabilized human prestin in complex with chloride | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... | 著者 | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | 登録日 | 2021-08-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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7V75
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![BU of 7v75 by Molmil](/molmil-images/mine/7v75) | Thermostabilized human prestin in complex with salicylate | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-HYDROXYBENZOIC ACID, CHOLESTEROL, ... | 著者 | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | 登録日 | 2021-08-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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7V74
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![BU of 7v74 by Molmil](/molmil-images/mine/7v74) | Thermostabilized human prestin in complex with sulfate | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, SULFATE ION, ... | 著者 | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | 登録日 | 2021-08-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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7E8D
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![BU of 7e8d by Molmil](/molmil-images/mine/7e8d) | NSD2 E1099K mutant bound to nucleosome | 分子名称: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | 著者 | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | 登録日 | 2021-03-01 | 公開日 | 2021-11-10 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2. Nat Commun, 12, 2021
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5Y5N
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![BU of 5y5n by Molmil](/molmil-images/mine/5y5n) | Crystal structure of human Sirtuin 2 in complex with a selective inhibitor | 分子名称: | 2-[[3-(2-phenylethoxy)phenyl]amino]benzamide, NAD-dependent protein deacetylase sirtuin-2, ZINC ION | 著者 | Mellini, P, Itoh, Y, Tsumoto, H, Li, Y, Suzuki, M, Tokuda, N, Kakizawa, T, Miura, Y, Takeuchi, J, Lahtela-Kakkonen, M, Suzuki, T. | 登録日 | 2017-08-09 | 公開日 | 2017-09-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Potent mechanism-based sirtuin-2-selective inhibition by anin situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site. Chem Sci, 8, 2017
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1WGN
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![BU of 1wgn by Molmil](/molmil-images/mine/1wgn) | Solution Structure of UBA domain of Human Ubiquitin Associated Protein 1 (UBAP1) | 分子名称: | ubiquitin associated protein | 著者 | Zhao, C, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-05-28 | 公開日 | 2004-11-28 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of UBA domain of Human Ubiquitin Associated Protein 1 (UBAP1) To be Published
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1WX6
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![BU of 1wx6 by Molmil](/molmil-images/mine/1wx6) | Solution structure of the SH3 domain of the human cytoplasmic protein NCK2 | 分子名称: | Cytoplasmic protein NCK2 | 著者 | Ohnishi, S, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-01-20 | 公開日 | 2005-07-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the SH3 domain of the human cytoplasmic protein NCK2 To be Published
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1X2K
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![BU of 1x2k by Molmil](/molmil-images/mine/1x2k) | Solution Structure of the SH3 Domain of Human osteoclast stimulating factor 1 (OSTF1) | 分子名称: | Osteoclast stimulating factor 1 | 著者 | Kamatari, Y.O, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-04-25 | 公開日 | 2005-10-25 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the SH3 Domain of Human osteoclast stimulating factor 1 (OSTF1) To be Published
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1X3C
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![BU of 1x3c by Molmil](/molmil-images/mine/1x3c) | Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 292 | 分子名称: | ZINC ION, Zinc finger protein 292 | 著者 | Yoneyama, M, Tomizawa, T, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-02 | 公開日 | 2005-11-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the C2H2 type zinc-binding domain of human zinc finger protein 292 To be Published
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1K36
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![BU of 1k36 by Molmil](/molmil-images/mine/1k36) | NMR Structure of human Epiregulin | 分子名称: | Epiregulin | 著者 | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | 登録日 | 2001-10-02 | 公開日 | 2003-09-30 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity Febs Lett., 553, 2003
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1K37
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![BU of 1k37 by Molmil](/molmil-images/mine/1k37) | NMR Structure of human Epiregulin | 分子名称: | Epiregulin | 著者 | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | 登録日 | 2001-10-02 | 公開日 | 2003-09-30 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity Febs Lett., 553, 2003
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2YT2
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![BU of 2yt2 by Molmil](/molmil-images/mine/2yt2) | Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK | 分子名称: | Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor | 著者 | Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-05 | 公開日 | 2008-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2 J.Struct.Funct.Genom., 11, 2010
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1X6A
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![BU of 1x6a by Molmil](/molmil-images/mine/1x6a) | Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2) | 分子名称: | LIM domain kinase 2, ZINC ION | 著者 | Nameki, N, Sasagawa, A, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-17 | 公開日 | 2005-11-17 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the second LIM domain of human LIM-kinase 2 (LIMK2) To be Published
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7VVL
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![BU of 7vvl by Molmil](/molmil-images/mine/7vvl) | PTH-bound human PTH1R in complex with Gs (class2) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVN
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![BU of 7vvn by Molmil](/molmil-images/mine/7vvn) | PTH-bound human PTH1R in complex with Gs (class4) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVK
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![BU of 7vvk by Molmil](/molmil-images/mine/7vvk) | PTH-bound human PTH1R in complex with Gs (class1) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVM
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![BU of 7vvm by Molmil](/molmil-images/mine/7vvm) | PTH-bound human PTH1R in complex with Gs (class3) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVJ
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![BU of 7vvj by Molmil](/molmil-images/mine/7vvj) | PTHrP-bound human PTH1R in complex with Gs | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVO
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![BU of 7vvo by Molmil](/molmil-images/mine/7vvo) | PTH-bound human PTH1R in complex with Gs (class5) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7V94
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![BU of 7v94 by Molmil](/molmil-images/mine/7v94) | Cryo-EM structure of the Cas12c2-sgRNA-target DNA ternary complex | 分子名称: | Cas12c2, sgRNA, target DNA (non target strand), ... | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-24 | 公開日 | 2022-04-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82, 2022
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7V93
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![BU of 7v93 by Molmil](/molmil-images/mine/7v93) | Cryo-EM structure of the Cas12c2-sgRNA binary complex | 分子名称: | cas12c2, sgRNA | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-24 | 公開日 | 2022-04-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82, 2022
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