2LHI
 
 | | Solution structure of Ca2+/CNA1 peptide-bound yCaM | | 分子名称: | CALCIUM ION, Calmodulin,Serine/threonine-protein phosphatase 2B catalytic subunit A1 | | 著者 | Ogura, K, Takahashi, K, Kobashigawa, Y, Yoshida, R, Itoh, H, Yazawa, M, Inagaki, F. | | 登録日 | 2011-08-10 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulin.
Genes Cells, 17, 2012
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2LHH
 | | Solution structure of Ca2+-bound yCaM | | 分子名称: | CALCIUM ION, Calmodulin | | 著者 | Ogura, K, Takahashi, K, Kobashigawa, Y, Yoshida, R, Itoh, H, Yazawa, M, Inagaki, F. | | 登録日 | 2011-08-10 | | 公開日 | 2012-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulin.
Genes Cells, 17, 2012
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7YV1
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | | 著者 | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | | 登録日 | 2022-08-18 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023
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1YGU
 | | Crystal structure of the tandem phosphatase domains of RPTP CD45 with a pTyr peptide | | 分子名称: | Leukocyte common antigen, Polyoma Middle T antigen | | 著者 | Nam, H, Poy, F, Saito, H, Frederick, C.A. | | 登録日 | 2005-01-05 | | 公開日 | 2005-02-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.
J.Exp.Med., 201, 2005
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5GUA
 | | Structure of biotin carboxyl carrier protein from pyrococcus horikoshi OT3 (delta N79) A138Y mutant | | 分子名称: | 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain | | 著者 | Yamada, K, Kunishima, N, Matsuura, Y, Nakai, K, Naitow, H, Fukasawa, Y, Tomii, K. | | 登録日 | 2016-08-26 | | 公開日 | 2017-08-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Designing better diffracting crystals of biotin carboxyl carrier protein from Pyrococcus horikoshii by a mutation based on the crystal-packing propensity of amino acids.
Acta Crystallogr D Struct Biol, 73, 2017
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5GU9
 | | Structure of biotin carboxyl carrier protein from pyrococcus horikoshi OT3 (delta N79) A138I mutant | | 分子名称: | 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain | | 著者 | Yamada, K, Kunishima, N, Matsuura, Y, Nakai, K, Naitow, H, Fukasawa, Y, Tomii, K. | | 登録日 | 2016-08-26 | | 公開日 | 2017-08-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Designing better diffracting crystals of biotin carboxyl carrier protein from Pyrococcus horikoshii by a mutation based on the crystal-packing propensity of amino acids.
Acta Crystallogr D Struct Biol, 73, 2017
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5GU8
 | | Structure of biotin carboxyl carrier protein from pyrococcus horikoshi OT3 (delta N79) wild type | | 分子名称: | 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain, SODIUM ION | | 著者 | Yamada, K, Kunishima, N, Matsuura, Y, Nakai, K, Naitow, H, Fukasawa, Y, Tomii, K. | | 登録日 | 2016-08-26 | | 公開日 | 2017-08-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Designing better diffracting crystals of biotin carboxyl carrier protein from Pyrococcus horikoshii by a mutation based on the crystal-packing propensity of amino acids.
Acta Crystallogr D Struct Biol, 73, 2017
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1UF2
 | | The Atomic Structure of Rice dwarf Virus (RDV) | | 分子名称: | Core protein P3, Outer capsid protein P8, Structural protein P7 | | 著者 | Nakagawa, A, Miyazaki, N, Taka, J, Naitow, H, Ogawa, A, Fujimoto, Z, Mizuno, H, Higashi, T, Watanabe, Y, Omura, T, Cheng, R.H, Tsukihara, T. | | 登録日 | 2003-05-23 | | 公開日 | 2003-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The atomic structure of rice dwarf virus reveals the self-assembly mechanism of component proteins.
Structure, 11, 2003
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1YGR
 | | Crystal structure of the tandem phosphatase domain of RPTP CD45 | | 分子名称: | CD45 Protein Tyrosine Phosphatase, T-cell Receptor CD3 zeta ITAM-1 | | 著者 | Nam, H.J, Poy, F, Saito, H, Frederick, C.A. | | 登録日 | 2005-01-05 | | 公開日 | 2005-02-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.
J.Exp.Med., 201, 2005
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5ZGO
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5WR6
 | | Thermolysin, liganded form with cryo condition 2 | | 分子名称: | CALCIUM ION, N-[(benzyloxy)carbonyl]-L-aspartic acid, Thermolysin, ... | | 著者 | Kunishima, N, Naitow, H, Matsuura, Y. | | 登録日 | 2016-11-29 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Protein-ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation
Acta Crystallogr D Struct Biol, 73, 2017
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5WR3
 | | Thermolysin, SFX liganded form with water-based carrier | | 分子名称: | CALCIUM ION, N-[(benzyloxy)carbonyl]-L-aspartic acid, Thermolysin, ... | | 著者 | Kunishima, N, Naitow, H, Matsuura, Y. | | 登録日 | 2016-11-29 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Protein-ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation
Acta Crystallogr D Struct Biol, 73, 2017
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5WR5
 | | Thermolysin, liganded form with cryo condition 1 | | 分子名称: | CALCIUM ION, N-[(benzyloxy)carbonyl]-L-aspartic acid, TETRAETHYLENE GLYCOL, ... | | 著者 | Kunishima, N, Naitow, H, Matsuura, Y. | | 登録日 | 2016-11-29 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Protein-ligand complex structure from serial femtosecond crystallography using soaked thermolysin microcrystals and comparison with structures from synchrotron radiation
Acta Crystallogr D Struct Biol, 73, 2017
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2D07
 | | Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase | | 分子名称: | G/T mismatch-specific thymine DNA glycosylase, Ubiquitin-like protein SMT3B | | 著者 | Baba, D, Maita, N, Jee, J.G, Uchimura, Y, Saitoh, H, Sugasawa, K, Hanaoka, F, Tochio, H, Hiroaki, H, Shirakawa, M. | | 登録日 | 2005-07-26 | | 公開日 | 2006-06-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase
J.Mol.Biol., 359, 2006
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2RPQ
 | | Solution Structure of a SUMO-interacting motif of MBD1-containing chromatin-associated factor 1 bound to SUMO-3 | | 分子名称: | Activating transcription factor 7-interacting protein 1, Small ubiquitin-related modifier 2 | | 著者 | Sekiyama, N, Ikegami, T, Yamane, T, Ikeguchi, M, Uchimura, Y, Baba, D, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | | 登録日 | 2008-07-07 | | 公開日 | 2008-10-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the small ubiquitin-like modifier (SUMO)-interacting motif of MBD1-containing chromatin-associated factor 1 bound to SUMO-3
J.Biol.Chem., 283, 2008
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3VZV
 | | Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor | | 分子名称: | 1-{[(5R,6S)-5,6-bis(4-chlorophenyl)-6-methyl-3-(propan-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2-yl]carbonyl}-N,N-dimethyl-L-prolinamide, E3 ubiquitin-protein ligase Mdm2 | | 著者 | Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. | | 登録日 | 2012-10-16 | | 公開日 | 2013-02-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold
Bioorg.Med.Chem.Lett., 23, 2013
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3W69
 | | Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor | | 分子名称: | (5R,6S)-2-[((2S,5R)-2-{[(3R)-4-acetyl-3-methylpiperazin-1-yl]carbonyl}-5-ethylpyrrolidin-1-yl)carbonyl]-5,6-bis(4-chlorophenyl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | | 著者 | Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. | | 登録日 | 2013-02-12 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Synthesis and evaluation of novel orally active p53-MDM2 interaction inhibitors
Bioorg.Med.Chem., 21, 2013
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3ASP
 | | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with A-antigen | | 分子名称: | Capsid protein, SODIUM ION, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | | 登録日 | 2010-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus
J.Virol., 86, 2012
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3AST
 | | Crystal structure of P domain Q389N mutant from Norovirus Funabashi258 stain in the complex with Lewis-b | | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | | 登録日 | 2010-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus
J.Virol., 86, 2012
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3ASQ
 | | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with H-antigen | | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | | 登録日 | 2010-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus
J.Virol., 86, 2012
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3ASR
 | | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with Lewis-a | | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | | 登録日 | 2010-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus
J.Virol., 86, 2012
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3ASS
 | | Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with Lewis-b | | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | | 登録日 | 2010-12-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus
J.Virol., 86, 2012
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3A4S
 | | The crystal structure of the SLD2:Ubc9 complex | | 分子名称: | NFATC2-interacting protein, SUMO-conjugating enzyme UBC9 | | 著者 | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | | 登録日 | 2009-07-14 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
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3A4R
 | | The crystal structure of SUMO-like domain 2 in Nip45 | | 分子名称: | 1,2-ETHANEDIOL, NFATC2-interacting protein, SULFATE ION | | 著者 | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | | 登録日 | 2009-07-14 | | 公開日 | 2010-02-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45
Proteins, 78, 2009
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1ION
 | | THE SEPTUM SITE-DETERMINING PROTEIN MIND COMPLEXED WITH MG-ADP FROM PYROCOCCUS HORIKOSHII OT3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROBABLE CELL DIVISION INHIBITOR MIND | | 著者 | Sakai, N, Yao, M, Itou, H, Watanabe, N, Yumoto, F, Tanokura, M, Tanaka, I. | | 登録日 | 2001-03-21 | | 公開日 | 2001-09-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The three-dimensional structure of septum site-determining protein MinD from Pyrococcus horikoshii OT3 in complex with Mg-ADP.
Structure, 9, 2001
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