1YGR

Crystal structure of the tandem phosphatase domain of RPTP CD45

Summary for 1YGR

Entry DOI	10.2210/pdb1ygr/pdb
Descriptor	CD45 Protein Tyrosine Phosphatase, T-cell Receptor CD3 zeta ITAM-1 (2 entities in total)
Functional Keywords	protein tyrosine phosphatase, rptp, cd45, lca, lymphocyte activation, cd3 zeta, itam, hydrolase
Biological source	Homo sapiens (human) More
Cellular location	Membrane ; Single-pass type I membrane protein : P08575 P20963
Total number of polymer chains	4
Total formula weight	144782.87
Authors	Nam, H.J.,Poy, F.,Saito, H.,Frederick, C.A. (deposition date: 2005-01-05, release date: 2005-02-22, Last modification date: 2021-10-20)
Primary citation	Nam, H.J.,Poy, F.,Saito, H.,Frederick, C.A. Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45. J.Exp.Med., 201:441-452, 2005 Cited by PubMed: 15684325 DOI: 10.1084/jem.20041890 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation