1YGR
Crystal structure of the tandem phosphatase domain of RPTP CD45
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | CD45 Protein Tyrosine Phosphatase | polymer | 610 | 71500.6 | 2 | UniProt (P08575) Pfam (PF00102) In PDB | Homo sapiens (human) | |
2 | C, D | T-cell Receptor CD3 zeta ITAM-1 | polymer | 6 | 890.8 | 2 | UniProt (P20963) In PDB |
Sequence modifications
A, B: 599 - 1208 (UniProt: P08575)
C, D: 2001 - 2006 (UniProt: P20963)
PDB | External Database | Details |
---|---|---|
Mse 603 | Met 626 | modified residue |
Pro 627 | Leu 650 | variant |
Mse 714 | Met 737 | modified residue |
Mse 725 | Met 748 | modified residue |
Mse 744 | Met 767 | modified residue |
Ser 828 | Cys 851 | engineered mutation |
Mse 844 | Met 867 | modified residue |
Mse 870 | Met 893 | modified residue |
Mse 907 | Met 930 | modified residue |
Mse 999 | Met 1022 | modified residue |
Mse 1007 | Met 1030 | modified residue |
Mse 1024 | Met 1047 | modified residue |
Mse 1035 | Met 1058 | modified residue |
Mse 1115 | Met 1138 | modified residue |
Leu 1184 | Pro 1207 | variant |
Mse 1186 | Met 1209 | modified residue |
PDB | External Database | Details |
---|---|---|
Ptr 2004 | Tyr 83 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 144782.9 | |
All* | Total formula weight | 144782.9 |