1YGR
Crystal structure of the tandem phosphatase domain of RPTP CD45
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:12522270 |
| Chain | Residue | Details |
| C | PTR2004 | |
| D | PTR2004 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Phosphocysteine intermediate => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP1146 | |
| B | ASP1146 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY798 | |
| A | ALA830 | |
| A | GLU874 | |
| B | GLY798 | |
| B | ALA830 | |
| B | GLU874 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P04157 |
| Chain | Residue | Details |
| A | ASP660 | |
| B | ASP660 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19367720, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | VAL952 | |
| B | VAL952 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | GLU971 | |
| B | GLU971 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P04157 |
| Chain | Residue | Details |
| A | HIS974 | |
| A | GLU978 | |
| A | ASP981 | |
| A | SER986 | |
| B | HIS974 | |
| B | GLU978 | |
| B | ASP981 | |
| B | SER986 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P06800 |
| Chain | Residue | Details |
| A | ASP982 | |
| B | ASP982 |
