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PDB: 17898 件

2XCC
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Crystal structure of PcrH from Pseudomonas aeruginosa
分子名称: REGULATORY PROTEIN PCRH
著者Job, V, Mattei, P.-J, Lemaire, D, Attree, I, Dessen, A.
登録日2010-04-22
公開日2010-05-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural Basis of Chaperone Recognition of Type III Secretion System Minor Translocator Proteins.
J.Biol.Chem., 285, 2010
2XGO
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XcOGT in complex with UDP-S-GlcNAc
分子名称: URIDINE-DIPHOSPHATE-1-DEOXY-1-THIO-N-ACETYLGLUCOSAMINE, XCOGT
著者Dorfmueller, H.C, Borodkin, V.S, Blair, D.E, Pathak, S, Navratilova, I, van Aalten, D.M.
登録日2010-06-07
公開日2010-08-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Substrate and Product Analogues as Human O-Glcnac Transferase Inhibitors.
Amino Acids, 40, 2011
2XCQ
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The 2.98A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase
分子名称: DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A
著者Bax, B.D, Chan, P.F, Eggleston, D.S, Fosberry, A, Gentry, D.R, Gorrec, F, Giordano, I, Hann, M.M, Hennessy, A, Hibbs, M, Huang, J, Jones, E, Jones, J, Brown, K.K, Lewis, C.J, May, E.W, Singh, O, Spitzfaden, C, Shen, C, Shillings, A, Theobald, A.F, Wohlkonig, A, Pearson, N.D, Gwynn, M.N.
登録日2010-04-24
公開日2010-08-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Nature, 466, 2010
4CVD
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Crystal structure of the central repeat of cell wall binding module of Cpl7
分子名称: LYSOZYME
著者Silva-Martin, N, Uson, I, Rodriguez, D.D, Hermoso, J.A.
登録日2014-03-25
公開日2015-04-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.666 Å)
主引用文献Deciphering how Cpl-7 cell wall-binding repeats recognize the bacterial peptidoglycan.
Sci Rep, 7, 2017
4OJ4
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Crystal structure of V290M PPARgamma mutant in complex with diclofenac
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, CALCIUM ION, Peroxisome proliferator-activated receptor gamma
著者Puhl, A.C, Webb, P, Polikarpov, I.
登録日2014-01-20
公開日2015-02-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a PPAR ligand-resistance syndrome mutant
To be Published
2XTR
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Structure of the P176A Colicin M mutant from E. coli
分子名称: COLICIN-M, NITRATE ION
著者Helbig, S, Patzer, S.I, Braun, V, Zeth, K.
登録日2010-10-12
公開日2010-12-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Activation of Colicin M by the Fkpa Prolyl Cis- Trans Isomerase/Chaperone.
J.Biol.Chem., 286, 2011
2XIU
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High resolution structure of MTSL-tagged CylR2.
分子名称: CYLR2, GLYCEROL, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
著者Gruene, T, Cho, M.-K, Karyagina, I, Kim, H.-Y, Grosse, C, Giller, K, Zweckstetter, M, Becker, S.
登録日2010-07-01
公開日2011-02-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Integrated Analysis of the Conformation of a Protein-Linked Spin Label by Crystallography, Epr and NMR Spectroscopy.
J.Biomol.NMR, 49, 2011
4E1P
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Crystal structure of the dimerization domain of Lsr2 from Mycobacterium tuberculosis in the P 1 21 1 space group
分子名称: Protein lsr2
著者Summers, E.L, Meindl, K, Uson, I, Arcus, V.L.
登録日2012-03-06
公開日2012-06-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.728 Å)
主引用文献The structure of the oligomerization domain of Lsr2 from Mycobacterium tuberculosis reveals a mechanism for chromosome organization and protection.
Plos One, 7, 2012
2YPF
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Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism
分子名称: 5'-D(*TP*AP*GP*AP*GP*GP*GP*TP*TP*AP*GP*GP*TP*TP *TP*AP*TP*AP*TP*AP*AP)-3', 5'-D(*TP*TP*TP*AP*TP*AP*TP*AP*AP*AP*CP*CP*TP*AP *AP*CP*CP*CP*TP*CP*TP*AP)-3', AVRBS3
著者Stella, S, Molina, R, Yefimenko, I, Prieto, J, Silva, G.H, Bertonati, C, Juillerat, A, Duchateau, P, Montoya, G.
登録日2012-10-30
公開日2013-08-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the Avrbs3-DNA Complex Provides New Insights Into the Initial Thymine-Recognition Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
4DJ2
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Unwinding the Differences of the Mammalian PERIOD Clock Proteins from Crystal Structure to Cellular Function
分子名称: Period circadian protein homolog 1
著者Kucera, N, Schmalen, I, Hennig, S, Oellinger, R, Strauss, H.M, Grudziecki, A, Wieczorek, C, Kramer, A, Wolf, E.
登録日2012-02-01
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YOH
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Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor
分子名称: 1-[[(2R,3S,5S)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methyl]-3-(4-nitrophenyl)urea, THYMIDYLATE KINASE
著者Huaqing, C, Carrero-Lerida, J, Silva, A.P.G, Whittingham, J.L, Brannigan, J.A, Ruiz-Perez, L.M, Read, K.D, Wilson, K.S, Gonzalez-Pacanowska, D, Gilbert, I.H.
登録日2012-10-24
公開日2013-07-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Synthesis and Evaluation of Alpha-Thymidine Analogues as Novel Antimalarials.
J.Med.Chem., 55, 2012
4DES
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BU of 4des by Molmil
Crystal Structure of the Wild Type TTR Binding Chrysin (TTRwt:CHR)
分子名称: Transthyretin, chrysin
著者Trivella, D.B.B, Polikarpov, I.
登録日2012-01-21
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012
2XQA
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Pentameric ligand gated ion channel GLIC in complex with tetrabutylantimony (TBSb)
分子名称: ANTIMONY (III) ION, GLR4197 PROTEIN
著者Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
登録日2010-09-01
公開日2010-11-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
4DJA
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Crystal structure of a prokaryotic (6-4) photolyase PhrB from Agrobacterium Tumefaciens with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore at 1.45A resolution
分子名称: 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
著者Scheerer, P, Zhang, F, Oberpichler, I, Lamparter, T, Krauss, N.
登録日2012-02-01
公開日2013-04-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of a prokaryotic (6-4) photolyase with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophore.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LZF
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A novel domain in the microcephaly protein CPAP suggests a role in centriole architecture
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal P4.1-associated protein, SCL-interrupting locus protein homolog, ...
著者Hatzopoulos, G.N, Erat, M.C, Cutts, E, Rogala, K, Slatter, L, Stansfeld, P.J, Vakonakis, I.
登録日2013-07-31
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture.
Structure, 21, 2013
2XQ6
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Pentameric ligand gated ion channel GLIC in complex with cesium ion (Cs+)
分子名称: CESIUM ION, GLR4197 PROTEIN
著者Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
登録日2010-09-01
公開日2010-11-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
4M6L
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Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and 5,10-dideazatetrahydrofolic acid
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydrofolate reductase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, ...
著者Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
登録日2013-08-09
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
2Y2C
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crystal structure of AmpD Apoenzyme
分子名称: 1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD
著者Carrasco-Lopez, C, Rojas-Altuve, A, Zhang, W, Hesek, D, Lee, M, Barbe, S, Andre, I, Silva-Martin, N, Martinez-Ripoll, M, Mobashery, S, Hermoso, J.A.
登録日2010-12-14
公開日2011-07-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism.
J.Biol.Chem., 286, 2011
4GCN
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N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
分子名称: Protein STI-1, TRIETHYLENE GLYCOL
著者Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-07-30
公開日2012-08-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans
To be Published
2XQ3
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Pentameric ligand gated ion channel GLIC in complex with Br-lidocaine
分子名称: BROMIDE ION, GLR4197 PROTEIN
著者Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R.
登録日2010-09-01
公開日2010-11-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel
Nat.Struct.Mol.Biol., 17, 2010
4GLP
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The crystal structure of soluble human CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket.
分子名称: Monocyte differentiation antigen CD14
著者Kelley, S.L, Lukk, T, Nair, S.K, Tapping, R.I.
登録日2012-08-14
公開日2012-12-26
最終更新日2021-05-26
実験手法X-RAY DIFFRACTION (4.002 Å)
主引用文献The Crystal Structure of Human Soluble CD14 Reveals a Bent Solenoid with a Hydrophobic Amino-Terminal Pocket.
J.Immunol., 190, 2013
4O9R
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Human Smoothened Receptor structure in complex with cyclopamine
分子名称: Cyclopamine, Smoothened homolog/Soluble cytochrome b562 chimeric protein
著者Wang, C, Weierstall, U, James, D, White, T.A, Wang, D, Liu, W, Spence, J.C.H, Doak, R.B, Nelson, G, Fromme, P, Fromme, R, Grotjohann, I, Kupitz, C, Zatsepin, N.A, Liu, H, Basu, S, Wacker, D, Han, G.W, Katritch, V, Boutet, S, Messerschmidt, M, Willams, G.J, Koglin, J.E, Seibert, M.M, Klinker, M, Gati, C, Shoeman, R.L, Barty, A, Chapman, H.N, Kirian, R.A, Beyerlein, K.R, Stevens, R.C, Li, D, Shah, S.T.A, Howe, N, Caffrey, M, Cherezov, V, GPCR Network (GPCR)
登録日2014-01-02
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.204 Å)
主引用文献Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography.
Nat Commun, 5, 2014
4P0B
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Crystal structure of HOIP PUB domain in complex with OTULIN PIM
分子名称: E3 ubiquitin-protein ligase RNF31, Ubiquitin thioesterase otulin
著者Akutsu, M, Schaeffer, V, Olma, M.H, Gomes, L.C, Kawasaki, M, Dikic, I.
登録日2014-02-20
公開日2014-05-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7005 Å)
主引用文献Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling.
Mol.Cell, 54, 2014
4OHJ
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Crystal structure of toxic shock syndrome toxin-1 (TSST-1) from Staphylococcus aureus
分子名称: Toxic shock syndrome toxin-1
著者Filippova, E.V, Shuvalova, L, Flores, K, Dubrovska, I, Bishop, B, Ngo, H, Yeats, C, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-01-17
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structure of toxic shock syndrome toxin-1 (TSST-1) from Staphylococcus aureus
To be Published
4DET
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BU of 4det by Molmil
Crystal Structure of the Wild Type TTR Binding Kaempferol (TTRwt:KAE)
分子名称: 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, Transthyretin
著者Trivella, D.B.B, Polikarpov, I.
登録日2012-01-22
公開日2012-11-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
J.Struct.Biol., 180, 2012

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