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PDB: 17822 件

2UUX
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Structure of the tryptase inhibitor TdPI from a tick
分子名称: SULFATE ION, TRYPTASE INHIBITOR
著者Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I.
登録日2007-03-08
公開日2007-04-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
3A80
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Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid (soaking 40seconds)
分子名称: (E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid, CALCIUM ION, Cationic trypsin
著者Yamane, J, Yao, M, Tanaka, I.
登録日2009-10-05
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献In-Crystal Chemical Ligation for Drug Discovery
To be Published
3A8C
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Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking with mixture of [(E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid] and [(E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid])
分子名称: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin
著者Yamane, J, Yao, M, Tanaka, I.
登録日2009-10-05
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献In-Crystal Chemical Ligation for Drug Discovery
To be Published
4Q6M
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Structural analysis of the apo-form of Helicobacter pylori Csd4, a D,L-carboxypeptidase
分子名称: CALCIUM ION, Conserved hypothetical secreted protein, GLYCEROL
著者Kim, H.S, Kim, J, Im, H.N, An, D.R, Lee, M, Hesek, D, Mobashery, S, Kim, J.Y, Cho, K, Yoon, H.J, Han, B.W, Lee, B.I, Suh, S.W.
登録日2014-04-23
公開日2014-11-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of muramyltripeptide by Helicobacter pylori Csd4, a D,L-carboxypeptidase controlling the helical cell shape
Acta Crystallogr.,Sect.D, 70, 2014
2ZZE
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BU of 2zze by Molmil
Crystal structure of alanyl-tRNA synthetase without oligomerization domain in lysine-methylated form
分子名称: Alanyl-tRNA synthetase, ZINC ION
著者Sokabe, M, Ose, T, Tokunaga, K, Nakamura, A, Nureki, O, Yao, M, Tanaka, I.
登録日2009-02-10
公開日2009-07-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The structure of alanyl-tRNA synthetase with editing domain.
Proc.Natl.Acad.Sci.USA, 106, 2009
2UV6
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Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP
分子名称: 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE
著者Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J.
登録日2007-03-09
公開日2007-05-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
Acta Crystallogr.,Sect.D, 63, 2007
4QGW
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Crystal sturcture of the R132K:R111L:L121D mutant of Cellular Retinoic Acid Binding ProteinII complexed with a synthetic ligand (Merocyanine) at 1.77 angstrom resolution
分子名称: (2E,4E,6E)-3-methyl-6-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)hexa-2,4-dienal, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular retinoic acid-binding protein 2
著者Nosrati, M, Yapici, I, Geiger, J.H.
登録日2014-05-26
公開日2015-01-28
最終更新日2015-02-11
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献"Turn-on" protein fluorescence: in situ formation of cyanine dyes.
J.Am.Chem.Soc., 137, 2015
2UVL
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Human BIR3 domain of Baculoviral Inhibitor of Apoptosis Repeat- Containing 3 (BIRC3)
分子名称: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3, GLYCEROL, ZINC ION
著者Moche, M, Lehtio, L, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Karlberg, T, Kotenyova, T, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Upsten, M, Van Den Berg, S, Weigelt, J, Nordlund, P.
登録日2007-03-12
公開日2007-03-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structures of Bir Domains from Human Naip and Ciap2.
Acta Crystallogr.,Sect.F, 65, 2009
3ACL
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Crystal Structure of Human Pirin in complex with Triphenyl Compound
分子名称: FE (II) ION, N-{[4-(benzyloxy)phenyl](methyl)-lambda~4~-sulfanylidene}-4-methylbenzenesulfonamide, Pirin
著者Okumura, H, Miyazaki, I, Simizu, S, Osada, H.
登録日2010-01-05
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A small-molecule inhibitor shows that pirin regulates migration of melanoma cells
Nat.Chem.Biol., 6, 2010
389D
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BU of 389d by Molmil
CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Berger, I, Tereshko, V, Ikeda, H, Marquez, V.E, Egli, M.
登録日1998-04-20
公開日1998-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.
Nucleic Acids Res., 26, 1998
3A3D
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BU of 3a3d by Molmil
Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae
分子名称: GLYCEROL, Penicillin-binding protein 4
著者Kawai, F, Roper, D.I, Park, S.-Y, Tame, J.R.H.
登録日2009-06-12
公開日2009-12-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae
J.Mol.Biol., 396, 2010
2UV7
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Crystal Structure of a CBS domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP
分子名称: 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ADENOSINE MONOPHOSPHATE
著者Day, P, Sharff, A, Parra, L, Cleasby, A, Williams, M, Horer, S, Nar, H, Redemann, N, Tickle, I, Yon, J.
登録日2007-03-09
公開日2007-05-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
Acta Crystallogr.,Sect.D, 63, 2007
2VDA
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BU of 2vda by Molmil
Solution structure of the SecA-signal peptide complex
分子名称: MALTOPORIN, TRANSLOCASE SUBUNIT SECA
著者Gelis, I, Bonvin, A.M.J.J, Keramisanou, D, Koukaki, M, Gouridis, G, Karamanou, S, Economou, A, Kalodimos, C.G.
登録日2007-10-01
公開日2007-11-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Signal-Sequence Recognition by the Translocase Motor Seca as Determined by NMR
Cell(Cambridge,Mass.), 131, 2007
3A7H
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BU of 3a7h by Molmil
Human MST3 kinase in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Serine/threonine kinase 24 (STE20 homolog, yeast)
著者Ko, T.P, Jeng, W.Y, Liu, C.I, Lai, M.D, Wang, A.H.J.
登録日2009-09-26
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structures of human MST3 kinase in complex with adenine, ADP and Mn2+.
Acta Crystallogr.,Sect.D, 66, 2010
3A7X
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Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking 45seconds)
分子名称: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ...
著者Yamane, J, Yao, M, Tanaka, I.
登録日2009-10-05
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献In-Crystal Chemical Ligation for Drug Discovery
To be Published
3A86
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Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking 30 seconds)
分子名称: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ...
著者Yamane, J, Yao, M, Tanaka, I.
登録日2009-10-05
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献In-Crystal Chemical Ligation for Drug Discovery
To be Published
3A7F
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Human MST3 kinase
分子名称: Serine/threonine kinase 24 (STE20 homolog, yeast)
著者Ko, T.P, Jeng, W.Y, Liu, C.I, Lai, M.D, Wang, A.H.J.
登録日2009-09-26
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of human MST3 kinase in complex with adenine, ADP and Mn2+.
Acta Crystallogr.,Sect.D, 66, 2010
3A81
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Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 8 hours)
分子名称: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ...
著者Yamane, J, Yao, M, Tanaka, I.
登録日2009-10-05
公開日2010-09-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献In-Crystal Chemical Ligation for Drug Discovery
To be Published
3AGK
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Crystal structure of archaeal translation termination factor, aRF1
分子名称: Peptide chain release factor subunit 1
著者Kobayashi, K, Kikuno, I, Ishitani, R, Ito, K, Nureki, O.
登録日2010-04-01
公開日2010-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Omnipotent role of archaeal elongation factor 1 alpha (EF1{alpha}) in translational elongation and termination, and quality control of protein synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
2VIE
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BU of 2vie by Molmil
Human BACE-1 in complex with N-((1S,2R)-1-benzyl-2-hydroxy-3-((1,1,5- trimethylhexyl)amino)propyl)-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl) benzamide
分子名称: BETA-SECRETASE 1, N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(1,1,5-trimethylhexyl)amino]propyl}-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide
著者Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Faller, A, Hawkins, J, Hussain, I, MacPherson, D, Maile, G, Matico, R, Milner, P, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Riddell, D, Rowland, P, Soleil, V, Smith, K, Stanway, S, Stemp, G, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Ward, J, Wayne, G.
登録日2007-11-30
公開日2008-01-29
最終更新日2019-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bace-1 Inhibitors Part 2: Identification of Hydroxy Ethylamines (Heas) with Reduced Peptidic Character.
Bioorg.Med.Chem.Lett., 18, 2008
2ZYL
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Crystal structure of 3-ketosteroid-9-alpha-hydroxylase (KshA) from M. tuberculosis
分子名称: FE (II) ION, FE2/S2 (INORGANIC) CLUSTER, POSSIBLE OXIDOREDUCTASE, ...
著者D'Angelo, I, Capyk, J, Strynadka, N, Eltis, L.
登録日2009-01-27
公開日2009-03-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis
J.Biol.Chem., 284, 2009
2ZYQ
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Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis
分子名称: D(-)-TARTARIC ACID, FE (II) ION, PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC
著者D'Angelo, I, Yam, K.C, Eltis, L.D, Strynadka, N.
登録日2009-01-28
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.
Plos Pathog., 5, 2009
3AGF
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Crystal structure of Bacillus glutaminase in the presence of 4.3M NaCl
分子名称: Glutaminase 1
著者Yoshimune, K, Shirakihara, Y, Yumoto, I.
登録日2010-03-30
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Salt-induced conformational change of salt-tolerant glutaminase from Micrococcus luteus K-3
To be Published
3AGE
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Crystal structure of Mglu in its L-glutamate binding form in the presence of 4.3M NaCl
分子名称: GLUTAMIC ACID, Salt-tolerant glutaminase
著者Yoshimune, K, Shirakihara, Y, Yumoto, I.
登録日2010-03-30
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Salt-induced conformational change of salt-tolerant glutaminase from Micrococcus luteus K-3
To be Published
3AI0
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Crystal structure of beta-glucosidase from termite Neotermes koshunensis in complex with para-nitrophenyl-beta-D-glucopyranoside
分子名称: 4-nitrophenyl beta-D-glucopyranoside, GLYCEROL, beta-glucosidase
著者Jeng, W.-Y, Liu, C.-I, Wang, A.H.-J.
登録日2010-05-06
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and functional analysis of three beta-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensis
J.Struct.Biol., 173, 2011

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件を2024-08-14に公開中

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