3A8C

Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking with mixture of [(E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid] and [(E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid])

Summary for 3A8C

Entry DOI	10.2210/pdb3a8c/pdb
Related	3A7T 3A7V 3A7W 3A7X 3A7Y 3A7Z 3A80 3A81 3A82 3A83 3A84 3A85 3A86 3A87 3A88 3A89 3A8A 3A8B 3A8D
Descriptor	Cationic trypsin, CALCIUM ION, (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, ... (4 entities in total)
Functional Keywords	in-crystal chemical ligation, disulfide bond, hydrolase, metal-binding, protease, secreted, serine protease, zymogen
Biological source	Bos taurus (bovine)
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	1
Total formula weight	23585.58
Authors	Yamane, J.,Yao, M.,Tanaka, I. (deposition date: 2009-10-05, release date: 2010-09-29, Last modification date: 2023-11-01)
Primary citation	Yamane, J.,Ooyabu, N.,Yao, M.,Takemoto, H.,Tanaka, I. In-Crystal Chemical Ligation for Drug Discovery To be Published,
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation