2ZYQ
Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis
Summary for 2ZYQ
Entry DOI | 10.2210/pdb2zyq/pdb |
Related | 2ZI8 |
Descriptor | PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC, FE (II) ION, D(-)-TARTARIC ACID, ... (4 entities in total) |
Functional Keywords | dioxygenase, extradiol, dhsa, tb, catechol, cholesterol, steroid, aromatic hydrocarbons catabolism, iron, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 67518.40 |
Authors | D'Angelo, I.,Yam, K.C.,Eltis, L.D.,Strynadka, N. (deposition date: 2009-01-28, release date: 2009-03-10, Last modification date: 2023-11-01) |
Primary citation | Yam, K.C.,D'Angelo, I.,Kalscheuer, R.,Zhu, H.,Wang, J.X.,Snieckus, V.,Ly, L.H.,Converse, P.J.,Jacobs, W.R.,Strynadka, N.,Eltis, L.D. Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis. Plos Pathog., 5:e1000344-e1000344, 2009 Cited by PubMed: 19300498DOI: 10.1371/journal.ppat.1000344 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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