3ACL

Crystal Structure of Human Pirin in complex with Triphenyl Compound

Summary for 3ACL

• Entry DOI: 10.2210/pdb3acl/pdb
• Related: 1J1L
• Descriptor: Pirin, FE (II) ION, N-{[4-(benzyloxy)phenyl](methyl)-lambda~4~-sulfanylidene}-4-methylbenzenesulfonamide, ... (4 entities in total)
• Functional Keywords: cupin, inhibitor, complex, iron, metal binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : O00625
• Total number of polymer chains: 1
• Total formula weight: 33443.64

Authors

Okumura, H.,Miyazaki, I.,Simizu, S.,Osada, H. (deposition date: 2010-01-05, release date: 2010-08-18, Last modification date: 2023-11-01)

• Primary citation: Miyazaki, I.,Simizu, S.,Okumura, H.,Takagi, S.,Osada, H.; A small-molecule inhibitor shows that pirin regulates migration of melanoma cells; Nat.Chem.Biol., 6:667-673, 2010; PubMed: 20711196; DOI: 10.1038/nchembio.423

Experimental method

X-RAY DIFFRACTION (2.35 Å)